Mixed connective tissue disease laboratory tests: Difference between revisions
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***Anemia | ***Anemia | ||
***Leucopenia | ***Leucopenia | ||
**Circulating immune complexes | |||
**Hypocomplementemia | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 15:37, 6 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
Laboratory Findings
- Laboratory findings consistent with the diagnosis of MCTD include:[1][2]
- Antibodies against the U1-ribonucleoprotein complex (anti U1RNP)
- Rheumatoid factor (RF)
- High CRP levels[3]
- Hypergammaglobulinemia[4]
- Complete blood count may shows:[5]
- Anemia
- Leucopenia
- Circulating immune complexes
- Hypocomplementemia
References
- ↑ Mimura Y, Ihn H, Jinnin M, Asano Y, Yamane K, Tamaki K (July 2006). "Rheumatoid factor isotypes in mixed connective tissue disease". Clin. Rheumatol. 25 (4): 572–4. doi:10.1007/s10067-005-0185-y. PMID 16391886.
- ↑ Ruiz Pombo M, Labrador Horrillo M, Selva O'Callaghan A (November 2004). "[Undifferentiated, overlapping and mixed connective tissue diseases]". Med Clin (Barc) (in Spanish; Castilian). 123 (18): 712–7. PMID 15563821.
- ↑ Bakri Hassan A, Rönnelid J, Gunnarsson I, Karlsson G, Berg L, Lundberg I (October 1998). "Increased serum levels of immunoglobulins, C-reactive protein, type 1 and type 2 cytokines in patients with mixed connective tissue disease". J. Autoimmun. 11 (5): 503–8. doi:10.1006/jaut.1998.0236. PMID 9802936.
- ↑ Hämeenkorpi R, Ruuska P, Forsberg S, Tiilikainen R, Mäkitalo R, Hakala M (1993). "More evidence of distinctive features of mixed connective tissue disease". Scand. J. Rheumatol. 22 (2): 63–8. PMID 8480140.
- ↑ Latuśkiewicz-Potemska J, Zygmunt A, Biernacka-Zielińska M, Stańczyk J, Smolewska E (October 2013). "Mixed connective tissue disease presenting with progressive scleroderma symptoms in a 10-year-old girl". Postepy Dermatol Alergol. 30 (5): 329–36. doi:10.5114/pdia.2013.38365. PMC 3858664. PMID 24353496.