Ankylosing spondylitis natural history, complications and prognosis: Difference between revisions
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**Radiographic spinal changes | **Radiographic spinal changes | ||
===Complications=== | ===Complications=== | ||
*Common complications of ankylosing spondylitis(AS) include: | *Common complications of ankylosing spondylitis(AS) include:<ref name="pmid24658834">{{cite journal |vauthors=Stolwijk C, Essers I, van Tubergen A, Boonen A, Bazelier MT, De Bruin ML, de Vries F |title=The epidemiology of extra-articular manifestations in ankylosing spondylitis: a population-based matched cohort study |journal=Ann. Rheum. Dis. |volume=74 |issue=7 |pages=1373–8 |date=July 2015 |pmid=24658834 |doi=10.1136/annrheumdis-2014-205253 |url=}}</ref> | ||
**Acute anterior uveitis | **Acute anterior uveitis | ||
**Inflammatory bowel disease | **Inflammatory bowel disease |
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Natural History, Complications, and Prognosis
Natural History[1][2][3]
- The natural history of ankylosing spondylitis(AS) remains poorly documented.
- The heterogeneity of the ankylosing spondylitis(AS) has made studies technically difficult.
- Documentation of the early course of ankylosing spondylitis(AS) has been limited by the lack of appropriate criteria to diagnose early.
- Modified New York criteria had played important role in the study of ankylosing spondylitis(AS).
- Rudwaleit pointed that ankylosing spondylitis(AS) passes through three stages [4][5]
- Pre-radiographic
- Radiographic sacroiliitis
- Radiographic spinal changes
Complications
- Common complications of ankylosing spondylitis(AS) include:[6]
- Acute anterior uveitis
- Inflammatory bowel disease
- Psoriasis
- Psychosocial issues
- Cardiovascular problems
- Pulmonary problems
- Osteopenia
- Fractures
- Neurologic manifestations
- Renal manifestations
Prognosis
- It's hard to predict the long-term effects for the people who are suffering with ankylosing spondylitis because it varies from person to person.
- The presence of hip involvement is associated with a particularly poor prognosis among patients with ankylosing spondylitis patients.[7]
- In many patients onset of the disease and symptoms varies.
- In a very small percentage of the patients with AS they develop life-threatening complications like abnormal heart rhythm or the aortic heart valve.
References
- ↑ Goie The HS, Steven MM, van der Linden SM, Cats A (August 1985). "Evaluation of diagnostic criteria for ankylosing spondylitis: a comparison of the Rome, New York and modified New York criteria in patients with a positive clinical history screening test for ankylosing spondylitis". Br. J. Rheumatol. 24 (3): 242–9. PMID 3160423.
- ↑ Robertson LP, Davis MJ (December 2004). "A longitudinal study of disease activity and functional status in a hospital cohort of patients with ankylosing spondylitis". Rheumatology (Oxford). 43 (12): 1565–8. doi:10.1093/rheumatology/keh386. PMID 15353608.
- ↑ van der Linden S, Valkenburg HA, Cats A (April 1984). "Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria". Arthritis Rheum. 27 (4): 361–8. PMID 6231933.
- ↑ Rudwaleit M, Landewé R, van der Heijde D, Listing J, Brandt J, Braun J, Burgos-Vargas R, Collantes-Estevez E, Davis J, Dijkmans B, Dougados M, Emery P, van der Horst-Bruinsma IE, Inman R, Khan MA, Leirisalo-Repo M, van der Linden S, Maksymowych WP, Mielants H, Olivieri I, Sturrock R, de Vlam K, Sieper J (June 2009). "The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal". Ann. Rheum. Dis. 68 (6): 770–6. doi:10.1136/ard.2009.108217. PMID 19297345.
- ↑ van den Berg R, van der Heijde DM (November 2010). "How should we diagnose spondyloarthritis according to the ASAS classification criteria: a guide for practicing physicians". Pol. Arch. Med. Wewn. 120 (11): 452–7. PMID 21102381.
- ↑ Stolwijk C, Essers I, van Tubergen A, Boonen A, Bazelier MT, De Bruin ML, de Vries F (July 2015). "The epidemiology of extra-articular manifestations in ankylosing spondylitis: a population-based matched cohort study". Ann. Rheum. Dis. 74 (7): 1373–8. doi:10.1136/annrheumdis-2014-205253. PMID 24658834.
- ↑ Vander Cruyssen B, Muñoz-Gomariz E, Font P, Mulero J, de Vlam K, Boonen A, Vazquez-Mellado J, Flores D, Vastesaeger N, Collantes E (January 2010). "Hip involvement in ankylosing spondylitis: epidemiology and risk factors associated with hip replacement surgery". Rheumatology (Oxford). 49 (1): 73–81. doi:10.1093/rheumatology/kep174. PMID 19605374.