Osteoarthritis causes

Osteoarthritis causes

Osteoarthritis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Robert G. Badgett, M.D. [2] Luke Rusowicz-Orazem, B.S.; Mohammadmain Rezazadehsaatlou [3], Irfan Dotani [4]

Causes

Osteoarthritis (OA) is a result of a variety of disorders that lead to structural and functional failure in involved joints. Osteoarthritis, traditionally, has been considered as a disease specifically related to articular cartilage. Presently, it's been proven that OA influencing the whole joint system consisted of capsule, and synovium, subchondral bone, cartilage, menisci, ligaments, and periarticular muscle.

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	Paget disease
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	Acromegaly, Hemochromatosis, hyperparathyroidism, Pituitary cancer, Pituitary tumors, Reduced sex hormones
Environmental	No underlying causes
Gastroenterologic	Hemochromatosis, Wilson disease
Genetic	Adam12, Alkaptonuria  , Asymmetric leg length, Bmp, Clip, Col11a2, Ehlers-danlos syndrome, Erg, Familial chondrocalcinosis, Frzb, Gdf5, Il10, Larsen syndrome  , Mcf2l, Mmp3, Multiple epiphyseal dysplasia  , Nail-patella syndrome  , Osteochondritis dissecans  , Spondyloepiphyseal dysplasia tarda  , Tgfb1, Thalassemia, Wilson disease
Hematologic	Diabetes, Hemochromatosis, Thalassemia
Iatrogenic	Meniscectomy, Surgery
Infectious Disease	Syringomyelia, Tabes dorsalis, Viral hepatitis
Musculoskeletal/Orthopedic	Aseptic necrosis of bone, Asymmetric leg length, Avascular necrosis, Chondrocalcinosis 1  , Chondrocalcinosis 2, Developmental dysplasia of the hip, Ehlers-danlos syndrome, Familial chondrocalcinosis, Fracture of bone, Joint injury, Meniscectomy, Multiple epiphyseal dysplasia  , Muscle dysfunction, Osteochondritis dissecans  , Syringomyelia, Tabes dorsalis
Neurologic	No underlying causes
Nutritional/Metabolic	Diabetes, Obesity
Obstetric/Gynecologic	No underlying causes
Oncologic	Pituitary cancer, Pituitary tumors
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Allergies, Aseptic necrosis of bone, Avascular necrosis, Chondrocalcinosis 1  , Chondrocalcinosis 2, Crystal deposition, Gout, Lupus, Rheumatoid arthritis, Satoyoshi syndrome
Sexual	No underlying causes
Trauma	Developmental dysplasia of the hip, Fracture of bone, Joint injury, Physical trauma, Trauma
Urologic	Alkaptonuria
Miscellaneous	Aging

Causes in Alphabetical Order

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