Antiphospholipid syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Feham Tariq, MD [2]

Overview

The incidence of antiphospholipid syndrome (APS) is approximately 5 cases per 100,000 persons per year. The prevalence of APS is approximately 40-50 cases per 100,000 persons worldwide. APS due to systemic lupus erythermatosus(SLE) is more commonly seen in the African American and Hispanic population. Middle aged women are more commonly affected by APS than males.

Epidemiology and Demographics

Incidence

• The incidence of antiphospholipid syndrome (APS) is approximately 5 cases per 100,000 persons per year.

Prevalence

• The prevalence of APS is approximately 40-50 cases per 100,000 persons worldwide.

Case-fatality rate/Mortality rate

• The case-fatality rate/mortality rate of catastrophic APS is approximately 50%.

Age

• The commonly affected age groups are young to middle aged adolescents.
• However, APS is also seen in children and elderly age group.

Race

• APS due to systemic lupus erythermatosus(SLE) is more commonly seen in the African American and Hispanic population.

Gender

• Middle aged women are more commonly affected by APS than males.

Region

• There is no particular regional predilection.