Methemoglobinemia other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
'''Congenital (Hereditary) Methemoglobinemia''' | |||
There are three main congenital conditions that lead to methemoglobinemia: | |||
1. Cytochrome b5 reductase deficiency and pyruvate kinase deficiency | |||
2. G6PD deficiency | |||
3. Presence of abnormal hemoglobin. | |||
'''Acquired or Acute Methemoglobinemia''' | |||
Most common cause include different oxidant drugs, toxins or chemicals | |||
==Other diagnostic studies== | ==Other diagnostic studies== | ||
Revision as of 11:17, 29 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
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Overview
Congenital (Hereditary) Methemoglobinemia
There are three main congenital conditions that lead to methemoglobinemia:
1. Cytochrome b5 reductase deficiency and pyruvate kinase deficiency
2. G6PD deficiency
3. Presence of abnormal hemoglobin.
Acquired or Acute Methemoglobinemia
Most common cause include different oxidant drugs, toxins or chemicals
Other diagnostic studies
Two additional bedside methods exist for detection of methemoglobin in the blood.
The first one includes insufflating 100% oxygen in a tube that contains the patient’s blood. IF the blood remains dark, probably the cause is because eof presence of MetHb.
The second one consist of placing couple of drops of blood on white filter paper, and check for change in the colour of the blood when you expose the paper to oxygen. Simply deoxygenated hemoglobin will change its colour from dark red to bright red, whereas methemoglobin will not.