Behçet's disease natural history, complications and prognosis

Behçet's disease Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

OR

Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].

OR

Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

• The symptoms of Behcet disease usually develop in the second to third decade of life, and start with symptoms such as ___.
• The symptoms of (disease name) typically develop ___ years after exposure to ___.
• If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

Complications

• Common complications of Behcet disease include:
  • Neuro Behcet
  • Vision loss
  • Aneurysm

Prognosis

• Depending on the extent of the disease at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as good.
• The worst prognoses are associated with retinal vasculitis, leading to blindness; vascular aneurysm formation, with possible rupture; and neuro–Behçet syndrome, which may lead to dementia despite appropriate aggressive treatment.