Minimal change disease risk factors: Difference between revisions
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== Overview == | == Overview == | ||
The cause of minimal change disease has not been identified or idiopathic. Nephrotic syndrome is most commonly as a result of damage to the clusters of tiny blood vessels (glomeruli). | The cause of [[minimal change disease]] has not been identified or [[idiopathic]]. [[Nephrotic syndrome]] is most commonly as a result of damage to the clusters of tiny blood vessels (glomeruli).But secondary causes may be due to Drugs, Toxins, [[Infection]], and [[Tumor]]. | ||
== Common Causes == | == Common Causes == | ||
Common risk factors in the development of minimal change disease include:<ref name="IijimaHamahira2002">{{cite journal|last1=Iijima|first1=Kazumoto|last2=Hamahira|first2=Kiyoshi|last3=Tanaka|first3=Ryojiro|last4=Kobayashi|first4=Akiko|last5=Nozu|first5=Kandai|last6=Nakamura|first6=Hajime|last7=Yoshikawa|first7=Norishige|title=Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome|journal=Kidney International|volume=61|issue=5|year=2002|pages=1801–1805|issn=00852538|doi=10.1046/j.1523-1755.2002.00303.x}}</ref> | Common [[Risk factor|risk factors]] in the development of [[minimal change disease]] include:<ref name="IijimaHamahira2002">{{cite journal|last1=Iijima|first1=Kazumoto|last2=Hamahira|first2=Kiyoshi|last3=Tanaka|first3=Ryojiro|last4=Kobayashi|first4=Akiko|last5=Nozu|first5=Kandai|last6=Nakamura|first6=Hajime|last7=Yoshikawa|first7=Norishige|title=Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome|journal=Kidney International|volume=61|issue=5|year=2002|pages=1801–1805|issn=00852538|doi=10.1046/j.1523-1755.2002.00303.x}}</ref> | ||
=== Common Risk Factors === | |||
*Children within the Age >1 year but <8 years | *Children within the Age >1 year but <8 years | ||
*[[ | *[[Hodgkin's lymphoma|Hodgkin lymphoma]] | ||
*[[ | *[[leukemia]] | ||
*[[ | *Recent [[viral]] illness | ||
*Toxins like Mercury, bee stings, fire coral exposure are one of the causes for minimal change disease. | *Toxins like [[Mercury]], [[bee]] stings, fire coral exposure are one of the causes for minimal change disease. | ||
*Drugs like<ref name="pmid279404603">{{cite journal |vauthors=Vivarelli M, Massella L, Ruggiero B, Emma F |title=Minimal Change Disease |journal=Clin J Am Soc Nephrol |volume=12 |issue=2 |pages=332–345 |date=February 2017 |pmid=27940460 |pmc=5293332 |doi=10.2215/CJN.05000516 |url=}}</ref> | *Drugs like<ref name="pmid279404603">{{cite journal |vauthors=Vivarelli M, Massella L, Ruggiero B, Emma F |title=Minimal Change Disease |journal=Clin J Am Soc Nephrol |volume=12 |issue=2 |pages=332–345 |date=February 2017 |pmid=27940460 |pmc=5293332 |doi=10.2215/CJN.05000516 |url=}}</ref> | ||
**Salazopyrin | **Salazopyrin | ||
**Mercury | **[[Mercury]] | ||
**Tiopronin | **[[Tiopronin]] | ||
**Lithium | **[[Lithium]] | ||
**D-penicillamine | **[[D-penicillamine]] | ||
**Gold | **[[Gold]] | ||
**Tyrosine-kinase inhibitor | **[[Tyrosine-kinase inhibitor]] | ||
=== Less Common Causes === | === Less Common Causes === | ||
Less common causes of minimal change disease include:<ref name="pmid279404602">{{cite journal |vauthors=Vivarelli M, Massella L, Ruggiero B, Emma F |title=Minimal Change Disease |journal=Clin J Am Soc Nephrol |volume=12 |issue=2 |pages=332–345 |date=February 2017 |pmid=27940460 |pmc=5293332 |doi=10.2215/CJN.05000516 |url=}}</ref><ref name="VivarelliMassella20172">{{cite journal|last1=Vivarelli|first1=Marina|last2=Massella|first2=Laura|last3=Ruggiero|first3=Barbara|last4=Emma|first4=Francesco|title=Minimal Change Disease|journal=Clinical Journal of the American Society of Nephrology|volume=12|issue=2|year=2017|pages=332–345|issn=1555-9041|doi=10.2215/CJN.05000516}}</ref> | Less common causes of minimal change disease include:<ref name="pmid279404602">{{cite journal |vauthors=Vivarelli M, Massella L, Ruggiero B, Emma F |title=Minimal Change Disease |journal=Clin J Am Soc Nephrol |volume=12 |issue=2 |pages=332–345 |date=February 2017 |pmid=27940460 |pmc=5293332 |doi=10.2215/CJN.05000516 |url=}}</ref><ref name="VivarelliMassella20172">{{cite journal|last1=Vivarelli|first1=Marina|last2=Massella|first2=Laura|last3=Ruggiero|first3=Barbara|last4=Emma|first4=Francesco|title=Minimal Change Disease|journal=Clinical Journal of the American Society of Nephrology|volume=12|issue=2|year=2017|pages=332–345|issn=1555-9041|doi=10.2215/CJN.05000516}}</ref> | ||
* Hepatitis B or C infection | * [[Hepatitis B]] or C infection | ||
* | * l[[Low birth weight|ow birth weigh]]<nowiki/>t (LBW) | ||
* Hematopoietic stem cell transplantation | * [[Hematopoietic]] stem cell transplantation | ||
{{Minimal change disease}} | {{Minimal change disease}} | ||
Revision as of 16:36, 12 June 2018
Overview
The cause of minimal change disease has not been identified or idiopathic. Nephrotic syndrome is most commonly as a result of damage to the clusters of tiny blood vessels (glomeruli).But secondary causes may be due to Drugs, Toxins, Infection, and Tumor.
Common Causes
Common risk factors in the development of minimal change disease include:[1]
Common Risk Factors
- Children within the Age >1 year but <8 years
- Hodgkin lymphoma
- leukemia
- Recent viral illness
- Toxins like Mercury, bee stings, fire coral exposure are one of the causes for minimal change disease.
- Drugs like[2]
- Salazopyrin
- Mercury
- Tiopronin
- Lithium
- D-penicillamine
- Gold
- Tyrosine-kinase inhibitor
Less Common Causes
Less common causes of minimal change disease include:[3][4]
- Hepatitis B or C infection
- low birth weight (LBW)
- Hematopoietic stem cell transplantation
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References
- ↑ Iijima, Kazumoto; Hamahira, Kiyoshi; Tanaka, Ryojiro; Kobayashi, Akiko; Nozu, Kandai; Nakamura, Hajime; Yoshikawa, Norishige (2002). "Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome". Kidney International. 61 (5): 1801–1805. doi:10.1046/j.1523-1755.2002.00303.x. ISSN 0085-2538.
- ↑ Vivarelli M, Massella L, Ruggiero B, Emma F (February 2017). "Minimal Change Disease". Clin J Am Soc Nephrol. 12 (2): 332–345. doi:10.2215/CJN.05000516. PMC 5293332. PMID 27940460.
- ↑ Vivarelli M, Massella L, Ruggiero B, Emma F (February 2017). "Minimal Change Disease". Clin J Am Soc Nephrol. 12 (2): 332–345. doi:10.2215/CJN.05000516. PMC 5293332. PMID 27940460.
- ↑ Vivarelli, Marina; Massella, Laura; Ruggiero, Barbara; Emma, Francesco (2017). "Minimal Change Disease". Clinical Journal of the American Society of Nephrology. 12 (2): 332–345. doi:10.2215/CJN.05000516. ISSN 1555-9041.