Vitamin B12 deficiency history and symptoms: Difference between revisions
Jump to navigation
Jump to search
Nabeel ahmed (talk | contribs) No edit summary |
m Bot: Removing from Primary care |
||
| Line 25: | Line 25: | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
Latest revision as of 00:42, 30 July 2020
|
Vitamin B12 deficiency Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Vitamin B12 deficiency history and symptoms On the Web |
|
American Roentgen Ray Society Images of Vitamin B12 deficiency history and symptoms |
|
Risk calculators and risk factors for Vitamin B12 deficiency history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History and Symptoms
Early symptoms
- Tiredness
- Decreased mental work capacity
- Decreased concentration and memory
- Irritability and depression
- Sleep disturbances because B12 involved in the regulation of the sleep wake cycle by the pineal gland (through melatonin).[1]
Neurological signs
- Sensory disturbances due to damage to peripheral nerves caused by demyelination and irreversible nerve cell death
- Numbness
- Tingling
- Ataxic gait
- Subacute combined degeneration of spinal cord
- mania and psychosis.[2][3]
- Bipolar disorder appears to genetically co-segregate with the hereditary B12-deficiency disorder pernicious anemia.[4][5]
References
- ↑ Hashimoto S, Kohsaka M, Morita N, Fukuda N, Honma S, Honma K (1996). "Vitamin B12 enhances the phase-response of circadian melatonin rhythm to a single bright light exposure in humans". Neurosci. Lett. 220 (2): 129–32. PMID 8981490.
- ↑ Sethi NK, Robilotti E, Sadan Y (2005). "Neurological Manifestations Of Vitamin B-12 Deficiency". The Internet Journal of Nutrition and Wellness. 2 (1).
- ↑ Masalha R, Chudakov B, Muhamad M, Rudoy I, Volkov I, Wirguin I (2001). "Cobalamin-responsive psychosis as the sole manifestation of vitamin B12 deficiency". Israeli Medical Association Journal. 3: 701–703.
- ↑ Reading CM. (1979). "X-linked dominant manic-depressive illness: Linkage with Xg blood-group, red-green color-blindness and vitamin-B12 deficiency". Orthomolecular Psychiatry. 8: 68–77.
- ↑ Reading CM. (1975). "Latent pernicious anemia: A preliminary report". Medical Journal of Australia. 40: 91–4.