Vitamin B12 deficiency causes: Difference between revisions
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===Cause in Alphabetical Order=== | ===Cause in Alphabetical Order=== | ||
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*[[Achlorhydria]] | *[[Achlorhydria]] | ||
*[[Atrophic gastritis]] | *[[Atrophic gastritis]] | ||
Revision as of 23:19, 10 January 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
Overview
Common causes of vitamin B12 deficiency include insufficient dietary intake, as well as diseases and iatrogenic procedures causing problems in absorption. It is common in individuals adhering to vegetarian or vegan diets without external supplementation, due to primary sources including animal products such as meat, eggs, and dairy.
Causes
Common Causes
- Insufficient diet
- Malabsorption syndrome
- Gastrectomy [1]
- Gastritis
- Ileal resection
- Postgastrectomy syndrome
- Crohn's disease [2]
- Celiac disease [3]
- Bariatric surgery
- Idiopathic
- Bacterial infection
- long term Metformin use [4]
Causes by Organ System
Cause in Alphabetical Order
- Achlorhydria
- Atrophic gastritis
- Bariatric surgery
- Blind loop syndrome
- Bothriocephalosis
- Celiac disease
- Chronic pancreatitis
- Cimetidine
- Cobalamin malabsorption
- Crohn's disease
- Diphyllobothrium latum
- Excessive alcohol consumption
- Gastrectomy
- Gastritis
- Glyburide
- Grasbeck-imerslund disease
- Graves' disease
- Homocystinuria
- Idiopathic
- Ileal resection
- Imerslund-najman-grasbeck anemia
- Insufficient diet
- Intrinsic factor deficiency
- Juvenile megaloblastic anemia
- Macrocytic anemia
- Malabsorption syndrome
- Megaloblastic anemia
- Metformin hydrochloride
- Mthfr deficiency
- N2o anesthesia
- Neomycin
- Nitroux oxide abuse
- Omeprazole
- Pancreatic insufficiency
- Pancreatitis
- Pantoprazole
- Pernicious anemia
- Postgastrectomy syndrome
- Prolonged antiacid use
- Rabeprazole
- Ranitidine hydrochloride
- Saxagliptin hydrochloride
- Small bowel disease
- Systemic lupus erythematosus
- Transcobalamin deficiency
- Veganism
- Vegetarianism
References
- ↑ Camarero-Shelly M, Pellitero S, Martínez E, Puig R, Leis A, Zavala R, Granada ML, Pastor C, Moreno P, Tarascó J, Balibrea J, Puig-Domingo M (April 2018). "[Vitamin B12 levels in the patient population attending an urban health centre in Madrid]". Semergen (in Spanish; Castilian). 44 (3): 161–167. doi:10.1016/j.semerg.2017.03.006. PMID 28457771.
- ↑ Gomollón F, Gargallo CJ, Muñoz JF, Vicente R, Lue A, Mir A, García-Alvarado M, Gracia M, García-López S (March 2017). "Oral Cyanocobalamin is Effective in the Treatment of Vitamin B12 Deficiency in Crohn's Disease". Nutrients. 9 (3). doi:10.3390/nu9030308. PMC 5372971. PMID 28335526.
- ↑ Orskov I, Orskov F (January 1966). "Episome-carried surface antigen K88 of Escherichia coli. I. Transmission of the determinant of the K88 antigen and influence on the transfer of chromosomal markers". J. Bacteriol. 91 (1): 69–75. PMID 5323299.
- ↑ de Jager J, Kooy A, Lehert P, Wulffelé MG, van der Kolk J, Bets D, Verburg J, Donker AJ, Stehouwer CD (May 2010). "Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial". BMJ. 340: c2181. PMC 2874129. PMID 20488910.