Leiomyosarcoma risk factors: Difference between revisions
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==Risk Factors== | ==Risk Factors== | ||
Clinical data has suggested that the development of leiomyosarcoma is related to [[radiation exposure]]. Other causes are not known for certain. | Clinical data has suggested that the development of leiomyosarcoma is related to [[radiation exposure]]. Other causes are not known for certain. | ||
== <small>Following Risk Fcators found to be associated with the development of the Uterine leiomyosarcoma</small>: == | |||
* Age: Leiomyosarcoma can be seen at 20 years of age but mean age at diagnosis is 50-60 years old. | |||
* Race:Black women have a higher incidence of development of the uterine leiomyosarcoma as compared to the white women. | |||
* Long term use of the tamoxifen: Prolonged use of the tamoxifen esp more than five years has been associated with the increased risk of development of leiomyosarcoma. | |||
* History of Pelvic radiations:Pelvic irradiation has been associated with the increased development of the leiomyosarcoma. | |||
* Certain Hereditary condition like Gardner syndrome, Li-Fraumeni syndrome,Werner syndrome and Neurofibromatosis are associated with the development of leiomyosarcoma. | |||
* Long term survivors of the Retinoblastoma are at higher risk of developing variety of soft tissue sarcoma. | |||
==References== | ==References== | ||
Revision as of 04:51, 13 June 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Risk Factors
Clinical data has suggested that the development of leiomyosarcoma is related to radiation exposure. Other causes are not known for certain.
Following Risk Fcators found to be associated with the development of the Uterine leiomyosarcoma:
- Age: Leiomyosarcoma can be seen at 20 years of age but mean age at diagnosis is 50-60 years old.
- Race:Black women have a higher incidence of development of the uterine leiomyosarcoma as compared to the white women.
- Long term use of the tamoxifen: Prolonged use of the tamoxifen esp more than five years has been associated with the increased risk of development of leiomyosarcoma.
- History of Pelvic radiations:Pelvic irradiation has been associated with the increased development of the leiomyosarcoma.
- Certain Hereditary condition like Gardner syndrome, Li-Fraumeni syndrome,Werner syndrome and Neurofibromatosis are associated with the development of leiomyosarcoma.
- Long term survivors of the Retinoblastoma are at higher risk of developing variety of soft tissue sarcoma.