Leiomyosarcoma physical examination: Difference between revisions
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=== Neuromuscular === | === Neuromuscular === | ||
* paresthesia due to the compression of the neurovascular bundle by the enlarging mass | * paresthesia due to the compression of the neurovascular bundle by the enlarging mass | ||
=== Paraneoplasic Syndrome manifestations === | |||
Rarely, Leiomyosarcoma presents with paraneoplastic hypoglycemia, which is usually secondary to the tumour production of insulin like growth factor-2<ref name="pmid8021581">Strauss G, Christensen L, Zapf J (1994) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=8021581 Tumour-induced hypoglycaemia due to 'big' IGF-II.] ''J Intern Med'' 236 (1):97-9. PMID: [https://pubmed.gov/8021581 8021581]</ref> | |||
==References== | ==References== | ||
Revision as of 08:28, 14 June 2018
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Overview
Patients with Leiomyosarcoma generally appear weak.Physical examination findings depends upon the site of the involvement,size and metastasis.Physical Examination findings may include weight loss, abdominal mass, Distension,Ascites, rectal bleeding and vaginal bleeding
Physical Examination
Physical examination findings depends upon the site of the involvement,size and metastasis.
Appearance of the Patient
- Patients with Leiomyosarcoma are generally weak due to weight loss.
Vital
Signs
Skin
- Jaundice may appear if the tumor develops in the inferior vena cava in the supra-hepatic segment
- Pallor
HEENT
Neck
Lungs
Dyspnea and chest pain in case of Leiomyosarcoma of the Pulmonary artert
Heart
Abdomen
- Non tender Abdominal mass
- Abdominal distension,hepatomegaly and ascites in case of Leiomyosarcoma of the inferior vena cava
Back
Rectum
- Blood on rectal Examination
Genitourinary
- Vaginal bleeding and discharge in case of uterine Leiomyosarcoma.
Extremities
Lower extremity edema if the tumors that arise in the inferior vena cava below the liver
Neuromuscular
- paresthesia due to the compression of the neurovascular bundle by the enlarging mass
Paraneoplasic Syndrome manifestations
Rarely, Leiomyosarcoma presents with paraneoplastic hypoglycemia, which is usually secondary to the tumour production of insulin like growth factor-2[1]
References
- ↑ Strauss G, Christensen L, Zapf J (1994) Tumour-induced hypoglycaemia due to 'big' IGF-II. J Intern Med 236 (1):97-9. PMID: 8021581