Lupus nephritis classification: Difference between revisions
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=== Minimal mesangial lupus nephritis (class I) === | === Minimal mesangial lupus nephritis (class I) === | ||
* Very rare. | |||
* No microscopic finding. | |||
* Identified on electron microscopy and immunofluorescence. | |||
=== Mesangial proliferative lupus nephritis (class II) === | === Mesangial proliferative lupus nephritis (class II) === | ||
* Microscopic Hematuria | |||
* Proteinuria | |||
* Hypercellularity in mesangium | |||
* Light microscopy shows subendothelial deposits or segmental scars | |||
* Immunofluorescence shows subepithelial or subendothelial deposits | |||
* Good prognosis | |||
=== Focal lupus nephritis (class III) === | === Focal lupus nephritis (class III) === | ||
* Less than 50% glomeruli involved | |||
* Hematuria | |||
* Proteinuria | |||
* Hypertension | |||
* Uniform involvement on immunofluorescence<ref name="pmid3656940">{{cite journal |vauthors=Schwartz MM, Kawala KS, Corwin HL, Lewis EJ |title=The prognosis of segmental glomerulonephritis in systemic lupus erythematosus |journal=Kidney Int. |volume=32 |issue=2 |pages=274–9 |date=August 1987 |pmid=3656940 |doi= |url=}}</ref> | |||
* Subendothelial immune and mesangial deposits on electron microscopy | |||
=== Diffuse lupus nephritis (class IV) === | === Diffuse lupus nephritis (class IV) === | ||
Revision as of 18:39, 11 July 2018
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Lupus nephritis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Lupus nephritis classification On the Web |
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American Roentgen Ray Society Images of Lupus nephritis classification |
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Risk calculators and risk factors for Lupus nephritis classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
There is no established system for the classification of [disease name].
OR
[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
OR
[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3]. [Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
OR
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
OR
If the staging system involves specific and characteristic findings and features: According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
OR
The staging of [malignancy name] is based on the [staging system].
OR
There is no established system for the staging of [malignancy name].
Classification
The Renal Pathology Society/International Society of Nephrology (RPS/ISN) classification:
Minimal mesangial lupus nephritis (class I)
- Very rare.
- No microscopic finding.
- Identified on electron microscopy and immunofluorescence.
Mesangial proliferative lupus nephritis (class II)
- Microscopic Hematuria
- Proteinuria
- Hypercellularity in mesangium
- Light microscopy shows subendothelial deposits or segmental scars
- Immunofluorescence shows subepithelial or subendothelial deposits
- Good prognosis
Focal lupus nephritis (class III)
- Less than 50% glomeruli involved
- Hematuria
- Proteinuria
- Hypertension
- Uniform involvement on immunofluorescence[1]
- Subendothelial immune and mesangial deposits on electron microscopy
Diffuse lupus nephritis (class IV)
Lupus membranous nephropathy (class V)
Advanced sclerosing lupus nephritis (class VI)
OR
- [Disease name] may be classified according to [classification method] into [number] subtypes/groups:
- [Group1]
- [Group2]
- [Group3]
- [Group4]
OR
- [Disease name] may be classified into [large number > 6] subtypes based on:
- [Classification method 1]
- [Classification method 2]
- [Classification method 3]
- [Disease name] may be classified into several subtypes based on:
- [Classification method 1]
- [Classification method 2]
- [Classification method 3]
OR
- Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
OR
- If the staging system involves specific and characteristic findings and features:
- According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
OR
- The staging of [malignancy name] is based on the [staging system].
OR
- There is no established system for the staging of [malignancy name].