Rapidly progressive glomerulonephritis x-ray findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2] Nazia Fuad M.D.

Overview

There are no x-ray findings associated with rapidly progressive glomerulonephritis unless it is associated with anti-GBM antibody disease (Goodpasture syndrome). On chest X-ray, Goodpasture syndrome is characterized by parenchymal consolidations that are most often present in both lungs, perihilar, and bibasilar. When pulmonary hemorrhage is recurrent an interstitial pattern is observed.

X Ray

• There are no x-ray findings associated with rapidly progressive glomerulonephritis, except in anti-GBM antibody (Goodpasture syndrome).
• In Goodpasture syndrome, chest x-ray findings include the following:
  • parenchymal consolidations.
  • Patients with Goodpasture syndrome have parenchymal consolidations from autoantibody induced inflammatory lesions that are most often present bilaterally in both lungs, in the perihilar, and bibasilar regions.
  • Unusual locations for parenchymal consolidations include the apices and the costophrenic angles.
  • 18% of patients with Goodpasture's syndrome may not show any signs of parenchymal consolidation, during the early stage of the disease.

Note: Diffuse alveolar hemorrhage throughout both lung fields in Goodpasture syndrome ([Case courtesy of Dr Sajoscha Sorrentino, <a href="https://radiopaedia.org/">Radiopaedia.org</a>])