Rapidly progressive glomerulonephritis physical examination: Difference between revisions
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* {{CMG}}; {{AE}} {{AEL}} {{N.F}} | * {{CMG}}; {{AE}} {{AEL}} {{N.F}} | ||
==Overview== | ==Overview== | ||
The physical examination results are usually normal. [[Hypertension]] can be present but is not common. When organs or systems are affected, they reveal different findings, which include [[leukocytoclastic vasculitis]], [[erythematous]] nodules due to necrotizing arteritis in skin.Patients may present with GI bleeding and [[pancreatitis]]. Other possible signs are [[arthritis]] and [[hematuria]]. | |||
==Physical examination== | ==Physical examination== | ||
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===Vital signs=== | ===Vital signs=== | ||
* Hypertension | * [[Hypertension]] | ||
===Skin=== | ===Skin=== | ||
* Leukocytoclastic vasculitis<ref name="pmid8089286">{{cite journal |vauthors=Daoud MS, Gibson LE, DeRemee RA, Specks U, el-Azhary RA, Su WP |title=Cutaneous Wegener's granulomatosis: clinical, histopathologic, and immunopathologic features of thirty patients |journal=J. Am. Acad. Dermatol. |volume=31 |issue=4 |pages=605–12 |date=October 1994 |pmid=8089286 |doi= |url=}}</ref> | * [[Leukocytoclastic vasculitis]]<ref name="pmid8089286">{{cite journal |vauthors=Daoud MS, Gibson LE, DeRemee RA, Specks U, el-Azhary RA, Su WP |title=Cutaneous Wegener's granulomatosis: clinical, histopathologic, and immunopathologic features of thirty patients |journal=J. Am. Acad. Dermatol. |volume=31 |issue=4 |pages=605–12 |date=October 1994 |pmid=8089286 |doi= |url=}}</ref> | ||
* Erythematous nodules due to necrotizing arteritis | * [[Erythematous]] nodules due to [[necrotizing arteritis]] | ||
* Granulomatous cutaneous nodules in patients present with granulomatosis with polyangitis | * Granulomatous cutaneous nodules in patients present with granulomatosis with polyangitis | ||
===Abdomen=== | ===Abdomen=== | ||
* Most of patients with ANCA +ve shows gastrointestinal involvement<ref name="pmid15758841">{{cite journal |vauthors=Pagnoux C, Mahr A, Cohen P, Guillevin L |title=Presentation and outcome of gastrointestinal involvement in systemic necrotizing vasculitides: analysis of 62 patients with polyarteritis nodosa, microscopic polyangiitis, Wegener granulomatosis, Churg-Strauss syndrome, or rheumatoid arthritis-associated vasculitis |journal=Medicine (Baltimore) |volume=84 |issue=2 |pages=115–28 |date=March 2005 |pmid=15758841 |doi= |url=}}</ref> | * Most of patients with [[Anti-neutrophil cytoplasmic antibody|ANCA]] +ve shows gastrointestinal involvement<ref name="pmid15758841">{{cite journal |vauthors=Pagnoux C, Mahr A, Cohen P, Guillevin L |title=Presentation and outcome of gastrointestinal involvement in systemic necrotizing vasculitides: analysis of 62 patients with polyarteritis nodosa, microscopic polyangiitis, Wegener granulomatosis, Churg-Strauss syndrome, or rheumatoid arthritis-associated vasculitis |journal=Medicine (Baltimore) |volume=84 |issue=2 |pages=115–28 |date=March 2005 |pmid=15758841 |doi= |url=}}</ref> | ||
* Occult GI bleeding as a result of ulceration due to arteritis | * [[Occult bleeding|Occult]] GI bleeding as a result of [[ulceration]] due to [[arteritis]] | ||
* Pancreatitis may be present | * [[Pancreatitis]] may be present | ||
===Neuromuscular=== | ===Neuromuscular=== | ||
* Mononeuritis multiplex in ANCA +ve patients<ref name="pmid28273992">{{cite journal |vauthors=Anadure R, Narayanan C, Varadraj G, Nandeesh B |title=ANCA Associated Mononeuritis Multiplex with Overlap in Vasculitic Syndromes |journal=J Clin Diagn Res |volume=11 |issue=1 |pages=OD01–OD03 |date=January 2017 |pmid=28273992 |pmc=5324437 |doi=10.7860/JCDR/2017/22252.9149 |url=}}</ref> | * [[Mononeuritis multiplex]] in [[Anti-neutrophil cytoplasmic antibody|ANCA]] +ve patients<ref name="pmid28273992">{{cite journal |vauthors=Anadure R, Narayanan C, Varadraj G, Nandeesh B |title=ANCA Associated Mononeuritis Multiplex with Overlap in Vasculitic Syndromes |journal=J Clin Diagn Res |volume=11 |issue=1 |pages=OD01–OD03 |date=January 2017 |pmid=28273992 |pmc=5324437 |doi=10.7860/JCDR/2017/22252.9149 |url=}}</ref> | ||
* Arthritis | * [[Arthritis]] | ||
* Arthralgia | * [[Arthralgia]] | ||
===Genitourinary === | ===Genitourinary === | ||
* Hematuria | * [[Hematuria]] | ||
==References== | ==References== |
Revision as of 14:42, 27 July 2018
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- Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2] Nazia Fuad M.D.
Overview
The physical examination results are usually normal. Hypertension can be present but is not common. When organs or systems are affected, they reveal different findings, which include leukocytoclastic vasculitis, erythematous nodules due to necrotizing arteritis in skin.Patients may present with GI bleeding and pancreatitis. Other possible signs are arthritis and hematuria.
Physical examination
Appearance of the patient
- Patients with rapidly progressive glomerulonephritis usually appear ill.
Vital signs
Skin
- Leukocytoclastic vasculitis[1]
- Erythematous nodules due to necrotizing arteritis
- Granulomatous cutaneous nodules in patients present with granulomatosis with polyangitis
Abdomen
- Most of patients with ANCA +ve shows gastrointestinal involvement[2]
- Occult GI bleeding as a result of ulceration due to arteritis
- Pancreatitis may be present
Neuromuscular
- Mononeuritis multiplex in ANCA +ve patients[3]
- Arthritis
- Arthralgia
Genitourinary
References
- ↑ Daoud MS, Gibson LE, DeRemee RA, Specks U, el-Azhary RA, Su WP (October 1994). "Cutaneous Wegener's granulomatosis: clinical, histopathologic, and immunopathologic features of thirty patients". J. Am. Acad. Dermatol. 31 (4): 605–12. PMID 8089286.
- ↑ Pagnoux C, Mahr A, Cohen P, Guillevin L (March 2005). "Presentation and outcome of gastrointestinal involvement in systemic necrotizing vasculitides: analysis of 62 patients with polyarteritis nodosa, microscopic polyangiitis, Wegener granulomatosis, Churg-Strauss syndrome, or rheumatoid arthritis-associated vasculitis". Medicine (Baltimore). 84 (2): 115–28. PMID 15758841.
- ↑ Anadure R, Narayanan C, Varadraj G, Nandeesh B (January 2017). "ANCA Associated Mononeuritis Multiplex with Overlap in Vasculitic Syndromes". J Clin Diagn Res. 11 (1): OD01–OD03. doi:10.7860/JCDR/2017/22252.9149. PMC 5324437. PMID 28273992.