Hamartoma epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
Revision as of 19:36, 13 September 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Vamsikrishna Gunnam M.B.B.S [3]
Overview
The incidence of pulmonary hamartoma is approximately 0.25% in general population.[1] The incidence of other hamartomas remains unknown.[2][3] Pulmonary hamartomas are estimated to be 8% of all lung neoplasms. Most lesions are diagnosed incidentally.[4][5] Hamartomatous syndromes are usually first diagnosed among adolescents and adult patients.[2] In general, most hamartomas affect males more commonly than females.[2]
Epidemiology and Demographics
Incidence
- The incidence of pulmonary hamartoma is approximately 0.25% in general population.[1][2][6]
- The incidence of bone-forming tumors is approximately 1% in general population.
- Pulmonary hamartomas are estimated to be 8% of all lung neoplasms. The majority of pulmonary hamartomas are diagnosed incidentally.[4][5]
- The incidence of other hamartomas remains unknown.
Age
- Pulmonary hamartomas are usually first diagnosed among patients in the 4th and 7th decades of life.[2]
- Bone islands often occur in children than adults.
- Pulmonary hamartomas are very uncommon in children.[2]
- Hypothalamic hamartomas are usually first diagnosed during puberty.[3]
- Cardiac hamartomas are usually first diagnosed among adolescents and young adults.[7]
- Kidney hamartomas are usually first diagnosed among middle age adults.[8]
Gender
- Males are more commonly affected with pulmonary hamartomas than females. The male to female ratio is approximately 3 to 1.[2]
- Males are slightly more affected with hypothalamic hamartomas than females. The male to female ratio is approximately 1.3 to 1.
- Females are more commonly affected with kidney hamartomas than males. The female to male ratio is approximately 4 to 1.
- Cardiac hamartoma affects males and females equally.
- Osteosarcomas most commonly affect males than females.
Race
- There is no racial predilection to hypothalamic hamartoma.[9]
References
- ↑ 1.0 1.1 Guo W, Zhao YP, Jiang YG, Wang RW, Ma Z (2008). "Surgical treatment and outcome of pulmonary hamartoma: a retrospective study of 20-year experience". Journal of Experimental & Clinical Cancer Research : CR. 27: 8. doi:10.1186/1756-9966-27-8. PMC 2438336. PMID 18577258.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Hansen CP, Holtveg H, Francis D, Rasch L, Bertelsen S (1992). "Pulmonary hamartoma". J. Thorac. Cardiovasc. Surg. 104 (3): 674–8. PMID 1513155.
- ↑ 3.0 3.1 Nguyen D, Singh S, Zaatreh M, Novotny E, Levy S, Testa F, Spencer SS (2003). "Hypothalamic hamartomas: seven cases and review of the literature". Epilepsy Behav. 4 (3): 246–58. PMID 12791326.
- ↑ 4.0 4.1 Murray J, Kielkowski D, Leiman G (1991). "The prevalence and age distribution of peripheral pulmonary hamartomas in adult males. An autopsy-based study". S. Afr. Med. J. 79 (5): 247–9. PMID 2011801.
- ↑ 5.0 5.1 Pulmonary hamartoma.Dr Henry Radiopedia.http://radiopaedia.org/articles/pulmonary-hamartoma-1 Accessed on December 08,2015
- ↑ Gjevre JA, Myers JL, Prakash UB (January 1996). "Pulmonary hamartomas". Mayo Clin. Proc. 71 (1): 14–20. doi:10.1016/S0025-6196(11)64915-X. PMID 8538225.
- ↑ Torimitsu S, Nemoto T, Wakayama M, Okubo Y, Yokose T, Kitahara K, Ozawa T, Nakayama H, Shinozaki M, Sasai D, Ishiwatari T, Takuma K, Shibuya K (2012). "Literature survey on epidemiology and pathology of cardiac fibroma". Eur. J. Med. Res. 17: 5. doi:10.1186/2047-783X-17-5. PMC 3351722. PMID 22472419.
- ↑ Eble JN (1998). "Angiomyolipoma of kidney". Seminars in Diagnostic Pathology. 15 (1): 21–40. PMID 9503504.
- ↑ Leiter Herrán F, Restrepo CS, Alvarez Gómez DI, Suby-Long T, Ocazionez D, Vargas D (March 2017). "Hamartomas from head to toe: an imaging overview". Br J Radiol. 90 (1071): 20160607. doi:10.1259/bjr.20160607. PMC 5601532. PMID 27936889.