Hamartoma CT: Difference between revisions
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==CT== | ==CT== | ||
*On computed tomography, common findings of pulmonary hamartoma, include:<ref name="pmid12376601">{{cite journal |vauthors=Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ |title=Fat-containing lesions of the chest |journal=Radiographics |volume=22 Spec No |issue= |pages=S61–78 |year=2002 |pmid=12376601 |doi=10.1148/radiographics.22.suppl_1.g02oc08s61 |url=}}</ref><ref name="hbook">Brant WE, Helms CA.(2007) Fundamentals of diagnostic radiology. Lippincott Williams & Wilkins.ISBN:0781765188</ref><ref name="SiegelmanKhouri1986">{{cite journal|last1=Siegelman|first1=S S|last2=Khouri|first2=N F|last3=Scott|first3=W W|last4=Leo|first4=F P|last5=Hamper|first5=U M|last6=Fishman|first6=E K|last7=Zerhouni|first7=E A|title=Pulmonary hamartoma: CT findings.|journal=Radiology|volume=160|issue=2|year=1986|pages=313–317|issn=0033-8419|doi=10.1148/radiology.160.2.3726106}}</ref><ref name="GaerteMeyer2002">{{cite journal|last1=Gaerte|first1=Scott C.|last2=Meyer|first2=Cristopher A.|last3=Winer-Muram|first3=Helen T.|last4=Tarver|first4=Robert D.|last5=Conces|first5=Dewey J.|title=Fat-containing Lesions of the Chest|journal=RadioGraphics|volume=22|issue=suppl_1|year=2002|pages=S61–S78|issn=0271-5333|doi=10.1148/radiographics.22.suppl_1.g02oc08s61}}</ref><ref name="pmid24119266">{{cite journal |vauthors=Gleeson T, Thiessen R, Hannigan A, Murphy D, English JC, Mayo JR |title=Pulmonary hamartomas: CT pixel analysis for fat attenuation using radiologic-pathologic correlation |journal=J Med Imaging Radiat Oncol |volume=57 |issue=5 |pages=534–43 |date=October 2013 |pmid=24119266 |doi=10.1111/1754-9485.12083 |url=}}</ref><ref name="pmid28775580">{{cite journal |vauthors=Singh H, Khanna SK, Chandran V, Jetley RK |title=PULMONARY HAMARTOMA |journal=Med J Armed Forces India |volume=55 |issue=1 |pages=79–80 |date=January 1999 |pmid=28775580 |pmc=5531795 |doi=10.1016/S0377-1237(17)30328-3 |url=}}</ref> | === Pulmonary Hamartoma === | ||
*On [[computed tomography]], common findings of pulmonary hamartoma, include:<ref name="pmid12376601">{{cite journal |vauthors=Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ |title=Fat-containing lesions of the chest |journal=Radiographics |volume=22 Spec No |issue= |pages=S61–78 |year=2002 |pmid=12376601 |doi=10.1148/radiographics.22.suppl_1.g02oc08s61 |url=}}</ref><ref name="hbook">Brant WE, Helms CA.(2007) Fundamentals of diagnostic radiology. Lippincott Williams & Wilkins.ISBN:0781765188</ref><ref name="SiegelmanKhouri1986">{{cite journal|last1=Siegelman|first1=S S|last2=Khouri|first2=N F|last3=Scott|first3=W W|last4=Leo|first4=F P|last5=Hamper|first5=U M|last6=Fishman|first6=E K|last7=Zerhouni|first7=E A|title=Pulmonary hamartoma: CT findings.|journal=Radiology|volume=160|issue=2|year=1986|pages=313–317|issn=0033-8419|doi=10.1148/radiology.160.2.3726106}}</ref><ref name="GaerteMeyer2002">{{cite journal|last1=Gaerte|first1=Scott C.|last2=Meyer|first2=Cristopher A.|last3=Winer-Muram|first3=Helen T.|last4=Tarver|first4=Robert D.|last5=Conces|first5=Dewey J.|title=Fat-containing Lesions of the Chest|journal=RadioGraphics|volume=22|issue=suppl_1|year=2002|pages=S61–S78|issn=0271-5333|doi=10.1148/radiographics.22.suppl_1.g02oc08s61}}</ref><ref name="pmid24119266">{{cite journal |vauthors=Gleeson T, Thiessen R, Hannigan A, Murphy D, English JC, Mayo JR |title=Pulmonary hamartomas: CT pixel analysis for fat attenuation using radiologic-pathologic correlation |journal=J Med Imaging Radiat Oncol |volume=57 |issue=5 |pages=534–43 |date=October 2013 |pmid=24119266 |doi=10.1111/1754-9485.12083 |url=}}</ref><ref name="pmid28775580">{{cite journal |vauthors=Singh H, Khanna SK, Chandran V, Jetley RK |title=PULMONARY HAMARTOMA |journal=Med J Armed Forces India |volume=55 |issue=1 |pages=79–80 |date=January 1999 |pmid=28775580 |pmc=5531795 |doi=10.1016/S0377-1237(17)30328-3 |url=}}</ref> | |||
:*Isodense or hypodense solid masses | :*Isodense or hypodense solid masses | ||
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:*[[Calcification]] is typically dispersed in the form of multiple lumps throughout the lesion in a [[popcorn]] configuration | :*[[Calcification]] is typically dispersed in the form of multiple lumps throughout the lesion in a [[popcorn]] configuration | ||
=== Spleen Hamartoma === | |||
*On [[computed tomography]], spleen [[hamartoma]] findings, include:<ref name="pmid25238476">{{cite journal |vauthors=Soto-Medina CA, Mier-Escurra EA, Treviño-Garza F, Ripa-Galván P |title=[Splenic hamartoma. Case report] |language=Spanish; Castilian |journal=Cirugía Y Cirujanos |volume=82 |issue=3 |pages=328–31 |year=2014 |pmid=25238476 |doi= |url=}}</ref> | *On [[computed tomography]], spleen [[hamartoma]] findings, include:<ref name="pmid25238476">{{cite journal |vauthors=Soto-Medina CA, Mier-Escurra EA, Treviño-Garza F, Ripa-Galván P |title=[Splenic hamartoma. Case report] |language=Spanish; Castilian |journal=Cirugía Y Cirujanos |volume=82 |issue=3 |pages=328–31 |year=2014 |pmid=25238476 |doi= |url=}}</ref> | ||
:*Isodense or hypodense solid masses | :*Isodense or hypodense solid masses | ||
:*Heterogeneous contrast enhancement relative to adjacent normal [[parenchyma]] | :*Heterogeneous contrast enhancement relative to adjacent normal [[parenchyma]] | ||
=== Renal Hamartoma === | |||
*On [[computed tomography]], common findings of renal [[hamartoma]], include:<ref name="pmid9503504">{{cite journal |vauthors=Eble JN |title=Angiomyolipoma of kidney |journal=Seminars in Diagnostic Pathology |volume=15 |issue=1 |pages=21–40 |year=1998 |pmid=9503504 |doi= |url=}}</ref> | *On [[computed tomography]], common findings of renal [[hamartoma]], include:<ref name="pmid9503504">{{cite journal |vauthors=Eble JN |title=Angiomyolipoma of kidney |journal=Seminars in Diagnostic Pathology |volume=15 |issue=1 |pages=21–40 |year=1998 |pmid=9503504 |doi= |url=}}</ref> | ||
:*Lesions involve the [[cortex]] and demonstrate macroscopic fat (less than -20 HU) | :*[[Lesion|Lesions]] involve the [[cortex]] and demonstrate macroscopic fat (less than -20 HU) | ||
:*Small renal [[hamartomas]] volume averaging may make differentiation from a small [[cyst]] difficult | :*Small renal [[hamartomas]] volume averaging may make differentiation from a small [[cyst]] difficult | ||
:*[[Renal]] hamartomas are [[fat]]-poor | :*[[Renal]] hamartomas are [[fat]]-poor | ||
:*[[Calcification]] is rare | :*[[Calcification]] is rare | ||
=== Hypothalamic Hamartoma === | |||
*On [[computed tomography]], common findings of [[Hypothalamus|hypothalamic]] [[hamartoma]], include:<ref name="pmid17544947">{{cite journal |vauthors=Fenoglio KA, Wu J, Kim do Y, Simeone TA, Coons SW, Rekate H, Rho JM, Kerrigan JF |title=Hypothalamic hamartoma: basic mechanisms of intrinsic epileptogenesis |journal=Seminars in Pediatric Neurology |volume=14 |issue=2 |pages=51–9 |year=2007 |pmid=17544947 |doi=10.1016/j.spen.2007.03.002 |url=http://linkinghub.elsevier.com/retrieve/pii/S1071-9091(07)00021-6}}</ref> | *On [[computed tomography]], common findings of [[Hypothalamus|hypothalamic]] [[hamartoma]], include:<ref name="pmid17544947">{{cite journal |vauthors=Fenoglio KA, Wu J, Kim do Y, Simeone TA, Coons SW, Rekate H, Rho JM, Kerrigan JF |title=Hypothalamic hamartoma: basic mechanisms of intrinsic epileptogenesis |journal=Seminars in Pediatric Neurology |volume=14 |issue=2 |pages=51–9 |year=2007 |pmid=17544947 |doi=10.1016/j.spen.2007.03.002 |url=http://linkinghub.elsevier.com/retrieve/pii/S1071-9091(07)00021-6}}</ref> | ||
:* Iso-attenuating nodule of soft-[[tissue]] | :* Iso-attenuating [[nodule]] of soft-[[tissue]] | ||
:* Calcification is rare | :* Calcification is rare | ||
:* There is no contrast [[enhancement]] | :* There is no contrast [[enhancement]] | ||
Revision as of 20:25, 18 September 2018
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Hamartoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Hamartoma CT On the Web |
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American Roentgen Ray Society Images of Hamartoma CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Vamsikrishna Gunnam M.B.B.S [3]
Overview
CT scan is the imaging modality of choice for the diagnosis of hamartoma. On CT scan, hamartoma is characterized by focal collections of fat, a lesion with a smooth edge, and collections of fat alternating with foci of calcification.
CT
Pulmonary Hamartoma
- Isodense or hypodense solid masses
- Heterogeneous contrast enhancement relative to adjacent normal parenchyma
- Presence of fat in a well circumscribed solitary pulmonary nodule which does not demonstrate significant growth
- The fat components may be localized or generalized within the nodule and will typically have a Hounsfield measurement of -40 to -120 HU
- Calcification is typically dispersed in the form of multiple lumps throughout the lesion in a popcorn configuration
Spleen Hamartoma
- On computed tomography, spleen hamartoma findings, include:[7]
- Isodense or hypodense solid masses
- Heterogeneous contrast enhancement relative to adjacent normal parenchyma
Renal Hamartoma
- On computed tomography, common findings of renal hamartoma, include:[8]
- Lesions involve the cortex and demonstrate macroscopic fat (less than -20 HU)
- Small renal hamartomas volume averaging may make differentiation from a small cyst difficult
- Renal hamartomas are fat-poor
- Calcification is rare
Hypothalamic Hamartoma
- On computed tomography, common findings of hypothalamic hamartoma, include:[9]
- Iso-attenuating nodule of soft-tissue
- Calcification is rare
- There is no contrast enhancement
Gallery
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CT scan (CT) shows a well circumcised lesion, with intralesional fat and calcification "popcorn-like appearance" adjacent to the hilum. -
CT scan (CT) shows an isodense solid mass in the inferior pole of the spleen.
References
- ↑ Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ (2002). "Fat-containing lesions of the chest". Radiographics. 22 Spec No: S61–78. doi:10.1148/radiographics.22.suppl_1.g02oc08s61. PMID 12376601.
- ↑ Brant WE, Helms CA.(2007) Fundamentals of diagnostic radiology. Lippincott Williams & Wilkins.ISBN:0781765188
- ↑ Siegelman, S S; Khouri, N F; Scott, W W; Leo, F P; Hamper, U M; Fishman, E K; Zerhouni, E A (1986). "Pulmonary hamartoma: CT findings". Radiology. 160 (2): 313–317. doi:10.1148/radiology.160.2.3726106. ISSN 0033-8419.
- ↑ Gaerte, Scott C.; Meyer, Cristopher A.; Winer-Muram, Helen T.; Tarver, Robert D.; Conces, Dewey J. (2002). "Fat-containing Lesions of the Chest". RadioGraphics. 22 (suppl_1): S61–S78. doi:10.1148/radiographics.22.suppl_1.g02oc08s61. ISSN 0271-5333.
- ↑ Gleeson T, Thiessen R, Hannigan A, Murphy D, English JC, Mayo JR (October 2013). "Pulmonary hamartomas: CT pixel analysis for fat attenuation using radiologic-pathologic correlation". J Med Imaging Radiat Oncol. 57 (5): 534–43. doi:10.1111/1754-9485.12083. PMID 24119266.
- ↑ Singh H, Khanna SK, Chandran V, Jetley RK (January 1999). "PULMONARY HAMARTOMA". Med J Armed Forces India. 55 (1): 79–80. doi:10.1016/S0377-1237(17)30328-3. PMC 5531795. PMID 28775580.
- ↑ Soto-Medina CA, Mier-Escurra EA, Treviño-Garza F, Ripa-Galván P (2014). "[Splenic hamartoma. Case report]". Cirugía Y Cirujanos (in Spanish; Castilian). 82 (3): 328–31. PMID 25238476.
- ↑ Eble JN (1998). "Angiomyolipoma of kidney". Seminars in Diagnostic Pathology. 15 (1): 21–40. PMID 9503504.
- ↑ Fenoglio KA, Wu J, Kim do Y, Simeone TA, Coons SW, Rekate H, Rho JM, Kerrigan JF (2007). "Hypothalamic hamartoma: basic mechanisms of intrinsic epileptogenesis". Seminars in Pediatric Neurology. 14 (2): 51–9. doi:10.1016/j.spen.2007.03.002. PMID 17544947.