Hairy cell leukemia physical examination: Difference between revisions
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=== Neck === | === Neck === | ||
* [[Lymphadenopathy]] can be found in 20% of the patients with [[hairy cell leukemia]]([[Hairy cell leukemia|HCL]]). | * [[Lymphadenopathy]] can be found in 20% of the patients with [[hairy cell leukemia]]([[Hairy cell leukemia|HCL]]). | ||
=== Lungs === | |||
* Pulmonary examination of patients with [[hairy cell leukemia]]([[Hairy cell leukemia|HCL]]) may be positive for [[pleural effusion]] but it's very rare finding.<ref name="GuzmanBross1991">{{cite journal|last1=Guzman|first1=Josune|last2=Bross|first2=Klaus J.|last3=Costabel|first3=Ulrich|title=Malignant lymphoma in pleural effusions: An immunocytochemical cell surface analysis|journal=Diagnostic Cytopathology|volume=7|issue=2|year=1991|pages=113–118|issn=87551039|doi=10.1002/dc.2840070202}}</ref> | |||
===Abdomen=== | ===Abdomen=== | ||
* Palpable [[splenomegaly]]: Can be found in around 80 to 90 percent of patients with [[hairy cell leukemia]]([[Hairy cell leukemia|HCL]]).<ref name="pmid7519510">{{cite journal |vauthors=Frassoldati A, Lamparelli T, Federico M, Annino L, Capnist G, Pagnucco G, Dini E, Resegotti L, Damasio EE, Silingardi V |title=Hairy cell leukemia: a clinical review based on 725 cases of the Italian Cooperative Group (ICGHCL). Italian Cooperative Group for Hairy Cell Leukemia |journal=Leuk. Lymphoma |volume=13 |issue=3-4 |pages=307–16 |date=April 1994 |pmid=7519510 |doi=10.3109/10428199409056295 |url=}}</ref> | * Palpable [[splenomegaly]]: Can be found in around 80 to 90 percent of patients with [[hairy cell leukemia]]([[Hairy cell leukemia|HCL]]).<ref name="pmid7519510">{{cite journal |vauthors=Frassoldati A, Lamparelli T, Federico M, Annino L, Capnist G, Pagnucco G, Dini E, Resegotti L, Damasio EE, Silingardi V |title=Hairy cell leukemia: a clinical review based on 725 cases of the Italian Cooperative Group (ICGHCL). Italian Cooperative Group for Hairy Cell Leukemia |journal=Leuk. Lymphoma |volume=13 |issue=3-4 |pages=307–16 |date=April 1994 |pmid=7519510 |doi=10.3109/10428199409056295 |url=}}</ref> | ||
* [[Hepatomegaly]] can be found in 20% of the patients with [[hairy cell leukemia]]([[Hairy cell leukemia|HCL]]).<ref name="pmid717940">{{cite journal |vauthors=Golomb HM, Catovsky D, Golde DW |title=Hairy cell leukemia: a clinical review based on 71 cases |journal=Ann. Intern. Med. |volume=89 |issue=5 Pt 1 |pages=677–83 |date=November 1978 |pmid=717940 |doi= |url=}}</ref> | * [[Hepatomegaly]] can be found in 20% of the patients with [[hairy cell leukemia]]([[Hairy cell leukemia|HCL]]).<ref name="pmid717940">{{cite journal |vauthors=Golomb HM, Catovsky D, Golde DW |title=Hairy cell leukemia: a clinical review based on 71 cases |journal=Ann. Intern. Med. |volume=89 |issue=5 Pt 1 |pages=677–83 |date=November 1978 |pmid=717940 |doi= |url=}}</ref> | ||
* [[Ascites]] | * [[Ascites]]. | ||
==References== | ==References== | ||
Revision as of 16:32, 15 November 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Physical examination of patients with hairy cell leukemia is usually remarkable for pallor, petechiae, and splenomegaly.
Physical Examination
The presence of palpable splenomegaly on physical examination is highly suggestive of hairy cell leukemia.
Appearance of the Patient
- Hairy cell leukemia patients often appear cachectic.
Vital Signs
- Fever: when positive it's a sigh of superimposed infection.
- Tachycardia with regular pulse.
Skin
Neck
- Lymphadenopathy can be found in 20% of the patients with hairy cell leukemia(HCL).
Lungs
- Pulmonary examination of patients with hairy cell leukemia(HCL) may be positive for pleural effusion but it's very rare finding.[1]
Abdomen
- Palpable splenomegaly: Can be found in around 80 to 90 percent of patients with hairy cell leukemia(HCL).[2]
- Hepatomegaly can be found in 20% of the patients with hairy cell leukemia(HCL).[3]
- Ascites.
References
- ↑ Guzman, Josune; Bross, Klaus J.; Costabel, Ulrich (1991). "Malignant lymphoma in pleural effusions: An immunocytochemical cell surface analysis". Diagnostic Cytopathology. 7 (2): 113–118. doi:10.1002/dc.2840070202. ISSN 8755-1039.
- ↑ Frassoldati A, Lamparelli T, Federico M, Annino L, Capnist G, Pagnucco G, Dini E, Resegotti L, Damasio EE, Silingardi V (April 1994). "Hairy cell leukemia: a clinical review based on 725 cases of the Italian Cooperative Group (ICGHCL). Italian Cooperative Group for Hairy Cell Leukemia". Leuk. Lymphoma. 13 (3–4): 307–16. doi:10.3109/10428199409056295. PMID 7519510.
- ↑ Golomb HM, Catovsky D, Golde DW (November 1978). "Hairy cell leukemia: a clinical review based on 71 cases". Ann. Intern. Med. 89 (5 Pt 1): 677–83. PMID 717940.