Multiple sclerosis historical perspective: Difference between revisions
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== Landmark Events in the Development of Treatment Strategies == | == Landmark Events in the Development of Treatment Strategies == | ||
== Famous Cases == | == Famous Cases == | ||
One of the first suspected [[MS]] patients in history is Saint Lidwina (1380-1433). She had [[symptoms]] such as [[pain]], [[lower extremities]] [[weakness]], and [[vision loss]].<ref>Charcot, J. ''Histologie de la sclerose en plaques.'' Gazette des hopitaux, Paris, 1868; 41: 554–555.</ref><ref>{{cite journal |author=Poser C |title=The dissemination of multiple sclerosis: a Viking saga? A historical essay |journal=Ann. Neurol. |volume=36 Suppl 2 |issue= |pages=S231-43 |year=1994 |pmid=7998792}}</ref> The other [[MS]] suspected patient in history is Augustus Frederick d’este (1794-1848). His [[symptoms]] began at the age of 28 with [[vision loss]], [[bladder]] dysfunction, [[numbness]], [[weakness]] of legs and [[sexual dysfunction]].<ref>{{cite book |last= Firth|first=D |title= The Case of August D`Esté|year=1948 |publisher=Cambridge University Press|location=Cambridge}}</ref> | * One of the first suspected [[MS]] patients in history is Saint Lidwina (1380-1433). She had [[symptoms]] such as [[pain]], [[lower extremities]] [[weakness]], and [[vision loss]].<ref>Charcot, J. ''Histologie de la sclerose en plaques.'' Gazette des hopitaux, Paris, 1868; 41: 554–555.</ref><ref>{{cite journal |author=Poser C |title=The dissemination of multiple sclerosis: a Viking saga? A historical essay |journal=Ann. Neurol. |volume=36 Suppl 2 |issue= |pages=S231-43 |year=1994 |pmid=7998792}}</ref> | ||
* The other [[MS]] suspected patient in history is Augustus Frederick d’este (1794-1848). His [[symptoms]] began at the age of 28 with [[vision loss]], [[bladder]] dysfunction, [[numbness]], [[weakness]] of legs and [[sexual dysfunction]].<ref>{{cite book |last= Firth|first=D |title= The Case of August D`Esté|year=1948 |publisher=Cambridge University Press|location=Cambridge}}</ref> | |||
==References== | ==References== | ||
Revision as of 23:51, 27 November 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Irfan Dotani
Overview
Multiple sclerosis was first described by a neurologist, Dr. Jean Martin Charcot in 1868 and named sclerose en plaque. The signs and symptoms including dysarthria, ataxia, and tremor were called 'Charcot’s triad'.
Historical Perspective
Discovery
- Multiple sclerosis was first described by a neurologist, Dr. Jean martin Charcot in 1868.
- Previously, Dr. Robert Hooper (1773-1835), Robert Carswell (1793-1857), and Jean Cruveilhier (1791-1873) had noticed some of the MS clinical manifestations, but for the first time, Dr. Charcot described it as a distinct disease and named sclerose en plaque.
- The signs and symptoms including dysarthria, ataxia, and tremor, were called charcot’s triad by Dr. Charcot for the first time.
Landmark Events in the Development of Treatment Strategies
Famous Cases
- One of the first suspected MS patients in history is Saint Lidwina (1380-1433). She had symptoms such as pain, lower extremities weakness, and vision loss.[1][2]
- The other MS suspected patient in history is Augustus Frederick d’este (1794-1848). His symptoms began at the age of 28 with vision loss, bladder dysfunction, numbness, weakness of legs and sexual dysfunction.[3]
References
- ↑ Charcot, J. Histologie de la sclerose en plaques. Gazette des hopitaux, Paris, 1868; 41: 554–555.
- ↑ Poser C (1994). "The dissemination of multiple sclerosis: a Viking saga? A historical essay". Ann. Neurol. 36 Suppl 2: S231–43. PMID 7998792.
- ↑ Firth, D (1948). The Case of August D`Esté. Cambridge: Cambridge University Press.