Hairy cell leukemia diagnotic study of choice: Difference between revisions
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==== Peripheral blood smear: ==== | ==== Peripheral blood smear: ==== | ||
[[Peripheral blood smear|Peripheral blood | [[Peripheral blood smear|Peripheral blood smear]] is one of the gold standard tests for the diagnosis of [[hairy cell leukemia]].<ref name="pmid6505703">{{cite journal |vauthors=Burke JS, Rappaport H |title=The diagnosis and differential diagnosis of hairy cell leukemia in bone marrow and spleen |journal=Semin. Oncol. |volume=11 |issue=4 |pages=334–46 |date=December 1984 |pmid=6505703 |doi= |url=}}</ref> | ||
The following result of [[Peripheral blood smear|peripheral blood smears]] is confirmatory of [[hairy cell leukemia]]: | The following result of [[Peripheral blood smear|peripheral blood smears]] is confirmatory of [[hairy cell leukemia]]: | ||
* Oval [[nuclei]] and abundant [[cytoplasm]] with "hairy" projections | * Oval [[nuclei]] and abundant [[cytoplasm]] with "hairy" projections | ||
* Fried egg appearance | * "Fried egg" appearance | ||
* Loose [[chromatin]] | * Loose [[chromatin]] | ||
* [[Mast cells]] numbers | * [[Mast cells]] numbers elevate | ||
* Extravasated red cells are positive in peripheral blood smear of [[hairy cell leukemia]] patients | * Extravasated red cells are positive in peripheral blood smear of [[hairy cell leukemia]] patients | ||
== References == | == References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Peripheral blood smears are the gold standard test for the diagnosis of hairy cell leukemia.
Diagnostic Study of Choice
Study of choice
Peripheral blood smear:
Peripheral blood smear is one of the gold standard tests for the diagnosis of hairy cell leukemia.[1]
The following result of peripheral blood smears is confirmatory of hairy cell leukemia:
- Oval nuclei and abundant cytoplasm with "hairy" projections
- "Fried egg" appearance
- Loose chromatin
- Mast cells numbers elevate
- Extravasated red cells are positive in peripheral blood smear of hairy cell leukemia patients