Blue rubber bleb nevus syndrome physical examination

Overview

The presence of skin lesions on physical examination is highly suggestive of blue rubber bleb nevus syndrome.

Physical Examination

Physical examination of patients with blue rubber bleb nevus syndrome is usually remarkable for cutaneous manifestations.

Appearance of the Patient

• Patients with blue rubber bleb nevus syndrome usually appear normal.

Vital Signs

• Tachycardia with regular pulse

Skin

• Skin lesions in patients with blue rubber bleb nevus syndrome classified into:
  • Cutaneous and
  • Extracutaneous manifestations

Cutaneous manifestations

• The skin lesions are usually multifocal venous malformations which are dark blue in colour
• These lesions vary from millimeters to centimeters in size and diameter
• Venous malformations number range from few to hundreds
• Skin lesions have been categorised into 3 types
  • Type 1: Blue, rubbery, blood-filled sacs
  • Type 2: Large, disfiguring, cavernous lesions
  • Type 3: Blue, irregular macules

Extracutaneous manifestations

• Apart from skin the most commonly organ that is involved in patients with blue rubber bleb nevus syndrome is GI tract
• In GI tract the most commonly involved region is small intestine
• The venous malformations in GI tract are prone to bleeding
• The bleeding of the venous malformations in GI tract may leads to iron deficiency anemia
• In severe cases the bleeding might even leads to death

Heart

• Cardiovascular examination of patients with blue rubber bleb nevus syndrome is usually normal

Neuromuscular

• Blue rubber bleb nevus is positive in area like
  • Skull
  • CNS
  • Musculoskeletal system

Lungs

• Pulmonary hypertension is due thromboembolic events is noticed in some patients with blue rubber bleb nevus syndrome

Blue rubber bleb nevus syndrome Microchapters
Home
Overview
Historical Perspective
Pathophysiology
Causes
Differentiating Blue Rubber Bleb Nevus Syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Blue rubber bleb nevus syndrome physical examination On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Blue rubber bleb nevus syndrome physical examination All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Blue rubber bleb nevus syndrome physical examination
CDC on Blue rubber bleb nevus syndrome physical examination
Blue rubber bleb nevus syndrome physical examination in the news
Blogs on Blue rubber bleb nevus syndrome physical examination
Directions to Hospitals Treating Blue rubber bleb nevus syndrome
Risk calculators and risk factors for Blue rubber bleb nevus syndrome physical examination