Guillain-Barré syndrome other diagnostic studies: Difference between revisions
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==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
* Nerve conduction studies and needle electromyography may be helpful in the diagnosis of Guillain Barre syndrome and differentiating various sub types. | * Nerve conduction studies and needle [[electromyography]] may be helpful in the diagnosis of Guillain Barre syndrome and differentiating various sub types. | ||
* Findings diagnostic of Guillain Barre syndrome include:<ref name="pmid9818934">{{cite journal |vauthors=Hadden RD, Cornblath DR, Hughes RA, Zielasek J, Hartung HP, Toyka KV, Swan AV |title=Electrophysiological classification of Guillain-Barré syndrome: clinical associations and outcome. Plasma Exchange/Sandoglobulin Guillain-Barré Syndrome Trial Group |journal=Ann. Neurol. |volume=44 |issue=5 |pages=780–8 |date=November 1998 |pmid=9818934 |doi=10.1002/ana.410440512 |url=}}</ref><ref name="pmid20855419">{{cite journal |vauthors=Kokubun N, Nishibayashi M, Uncini A, Odaka M, Hirata K, Yuki N |title=Conduction block in acute motor axonal neuropathy |journal=Brain |volume=133 |issue=10 |pages=2897–908 |date=October 2010 |pmid=20855419 |doi=10.1093/brain/awq260 |url=}}</ref><ref name="pmid26948435">{{cite journal |vauthors=Willison HJ, Jacobs BC, van Doorn PA |title=Guillain-Barré syndrome |journal=Lancet |volume=388 |issue=10045 |pages=717–27 |date=August 2016 |pmid=26948435 |doi=10.1016/S0140-6736(16)00339-1 |url=}}</ref> | * Findings diagnostic of Guillain Barre syndrome include:<ref name="pmid9818934">{{cite journal |vauthors=Hadden RD, Cornblath DR, Hughes RA, Zielasek J, Hartung HP, Toyka KV, Swan AV |title=Electrophysiological classification of Guillain-Barré syndrome: clinical associations and outcome. Plasma Exchange/Sandoglobulin Guillain-Barré Syndrome Trial Group |journal=Ann. Neurol. |volume=44 |issue=5 |pages=780–8 |date=November 1998 |pmid=9818934 |doi=10.1002/ana.410440512 |url=}}</ref><ref name="pmid20855419">{{cite journal |vauthors=Kokubun N, Nishibayashi M, Uncini A, Odaka M, Hirata K, Yuki N |title=Conduction block in acute motor axonal neuropathy |journal=Brain |volume=133 |issue=10 |pages=2897–908 |date=October 2010 |pmid=20855419 |doi=10.1093/brain/awq260 |url=}}</ref><ref name="pmid26948435">{{cite journal |vauthors=Willison HJ, Jacobs BC, van Doorn PA |title=Guillain-Barré syndrome |journal=Lancet |volume=388 |issue=10045 |pages=717–27 |date=August 2016 |pmid=26948435 |doi=10.1016/S0140-6736(16)00339-1 |url=}}</ref> | ||
** In demyelinating forms: | ** In [[demyelinating]] forms: | ||
*** Reduced conduction velocity of motor nerves. | *** Reduced conduction velocity of [[motor nerves]]. | ||
*** Increased distal motor latency. | *** Increased distal motor latency. | ||
*** increased latency of F wave. | *** increased latency of F wave. | ||
*** conduction block | *** conduction block | ||
*** Temporal scattering | *** Temporal scattering | ||
** In axonal forms: | ** In [[Axon|axonal]] forms: | ||
*** Reduced amplitude of distal motor and/or sensory nerve impulses. | *** Reduced amplitude of distal motor and/or sensory nerve impulses. | ||
*** Conduction block of motor nerves. | *** Conduction block of motor nerves. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Priyamvada Singh, MBBS [2]
Overview
Nerve conduction study may show prolonged distal latencies, conduction slowing, conduction block, and temporal dispersion of compound action potential in demyelinating cases. Forced vital capacities also help in taking decisions regarding ventilators [1].
Other Diagnostic Studies
- Nerve conduction studies and needle electromyography may be helpful in the diagnosis of Guillain Barre syndrome and differentiating various sub types.
- Findings diagnostic of Guillain Barre syndrome include:[2][3][4]
- In demyelinating forms:
- Reduced conduction velocity of motor nerves.
- Increased distal motor latency.
- increased latency of F wave.
- conduction block
- Temporal scattering
- In axonal forms:
- Reduced amplitude of distal motor and/or sensory nerve impulses.
- Conduction block of motor nerves.
- In demyelinating forms:
References
- ↑ Teitelbaum JS, Borel CO (1994). "Respiratory dysfunction in Guillain-Barré syndrome". Clinics in Chest Medicine. 15 (4): 705–14. PMID 7867285. Unknown parameter
|month=ignored (help);|access-date=requires|url=(help) - ↑ Hadden RD, Cornblath DR, Hughes RA, Zielasek J, Hartung HP, Toyka KV, Swan AV (November 1998). "Electrophysiological classification of Guillain-Barré syndrome: clinical associations and outcome. Plasma Exchange/Sandoglobulin Guillain-Barré Syndrome Trial Group". Ann. Neurol. 44 (5): 780–8. doi:10.1002/ana.410440512. PMID 9818934.
- ↑ Kokubun N, Nishibayashi M, Uncini A, Odaka M, Hirata K, Yuki N (October 2010). "Conduction block in acute motor axonal neuropathy". Brain. 133 (10): 2897–908. doi:10.1093/brain/awq260. PMID 20855419.
- ↑ Willison HJ, Jacobs BC, van Doorn PA (August 2016). "Guillain-Barré syndrome". Lancet. 388 (10045): 717–27. doi:10.1016/S0140-6736(16)00339-1. PMID 26948435.