Blue rubber bleb nevus syndrome medical therapy: Difference between revisions
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== Medical Therapy == | == Medical Therapy == | ||
* Pharmacologic medical therapies for [[blue rubber bleb nevus syndrome]] include:<ref name="pmid19958301">{{cite journal |vauthors=Agnese M, Cipolletta L, Bianco MA, Quitadamo P, Miele E, Staiano A |title=Blue rubber bleb nevus syndrome |journal=Acta Paediatr. |volume=99 |issue=4 |pages=632–5 |date=April 2010 |pmid=19958301 |doi=10.1111/j.1651-2227.2009.01608.x |url=}}</ref><ref name="pmid9795507">{{cite journal |vauthors=Jain A, Kar P, Chander R, Khandpur S, Jain S, Prabhash K, Gangwal P |title=Blue rubber bleb nevus syndrome: a cause of gastrointestinal hemorrhage |journal=Indian J Gastroenterol |volume=17 |issue=4 |pages=153–4 |date=1998 |pmid=9795507 |doi= |url=}}</ref><ref name="Jin2014">{{cite journal|last1=Jin|first1=Xue-Li|title=Blue rubber bleb nevus syndrome: A case report and literature review|journal=World Journal of Gastroenterology|volume=20|issue=45|year=2014|pages=17254|issn=1007-9327|doi=10.3748/wjg.v20.i45.17254}}</ref><ref name="BoenteCordisco1999">{{cite journal|last1=Boente|first1=Maria del C.|last2=Cordisco|first2=Maria R.|last3=Frontini|first3=Maria del V.|last4=Asial|first4=Raul A.|title=Blue Rubber Bleb Nevus (Bean Syndrome): Evolution of Four Cases and Clinical Response to Pharmacologic Agents|journal=Pediatric Dermatology|volume=16|issue=3|year=1999|pages=222–227|issn=0736-8046|doi=10.1046/j.1525-1470.1999.00065.x}}</ref> | * Pharmacologic medical therapies for [[blue rubber bleb nevus syndrome]] include:<ref name="pmid19958301">{{cite journal |vauthors=Agnese M, Cipolletta L, Bianco MA, Quitadamo P, Miele E, Staiano A |title=Blue rubber bleb nevus syndrome |journal=Acta Paediatr. |volume=99 |issue=4 |pages=632–5 |date=April 2010 |pmid=19958301 |doi=10.1111/j.1651-2227.2009.01608.x |url=}}</ref><ref name="pmid9795507">{{cite journal |vauthors=Jain A, Kar P, Chander R, Khandpur S, Jain S, Prabhash K, Gangwal P |title=Blue rubber bleb nevus syndrome: a cause of gastrointestinal hemorrhage |journal=Indian J Gastroenterol |volume=17 |issue=4 |pages=153–4 |date=1998 |pmid=9795507 |doi= |url=}}</ref><ref name="Jin2014">{{cite journal|last1=Jin|first1=Xue-Li|title=Blue rubber bleb nevus syndrome: A case report and literature review|journal=World Journal of Gastroenterology|volume=20|issue=45|year=2014|pages=17254|issn=1007-9327|doi=10.3748/wjg.v20.i45.17254}}</ref><ref name="BoenteCordisco1999">{{cite journal|last1=Boente|first1=Maria del C.|last2=Cordisco|first2=Maria R.|last3=Frontini|first3=Maria del V.|last4=Asial|first4=Raul A.|title=Blue Rubber Bleb Nevus (Bean Syndrome): Evolution of Four Cases and Clinical Response to Pharmacologic Agents|journal=Pediatric Dermatology|volume=16|issue=3|year=1999|pages=222–227|issn=0736-8046|doi=10.1046/j.1525-1470.1999.00065.x}}</ref><ref name="OguAbusin2018">{{cite journal|last1=Ogu|first1=Ugochi O.|last2=Abusin|first2=Ghada|last3=Abu-Arja|first3=Rolla F.|last4=Staber|first4=Janice M.|title=Successful Management of Blue Rubber Bleb Nevus Syndrome (BRBNS) with Sirolimus|journal=Case Reports in Pediatrics|volume=2018|year=2018|pages=1–5|issn=2090-6803|doi=10.1155/2018/7654278}}</ref> | ||
* Preferred regimen (1):[[Interferon-beta]] | * Preferred regimen (1):[[Interferon-beta]], 1.2 mg/m<sup>2</sup>/day for 2 months | ||
* Preferred regimen (2):[[Octreotide]] | * Preferred regimen (2):[[Octreotide]] | ||
Revision as of 15:39, 24 January 2019
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Blue rubber bleb nevus syndrome Microchapters |
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Differentiating Blue Rubber Bleb Nevus Syndrome from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Blue rubber bleb nevus syndrome medical therapy On the Web |
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American Roentgen Ray Society Images of Blue rubber bleb nevus syndrome medical therapy |
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Directions to Hospitals Treating Blue rubber bleb nevus syndrome |
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Risk calculators and risk factors for Blue rubber bleb nevus syndrome medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Vamsikrishna Gunnam M.B.B.S [2]
Overview
The mainstay of treatment for blue rubber bleb nevus syndrome is interferon-beta, octreotide, iron supplementation and blood transfusions.
Medical Therapy
- Pharmacologic medical therapies for blue rubber bleb nevus syndrome include:[1][2][3][4][5]
- Preferred regimen (1):Interferon-beta, 1.2 mg/m2/day for 2 months
- Preferred regimen (2):Octreotide
- Preferred regimen (3):Sirolimus [6]
- Preferred regimen (4):Iron supplementation
- Preferred regimen (5):Blood transfusions
- Preferred regimen (6):Corticosteroids
- Preferred regimen (7):Propranolol
- Preferred regimen (8):Thalidomide
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Blue rubber bleb nevus syndrome Microchapters |
|
Differentiating Blue Rubber Bleb Nevus Syndrome from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Blue rubber bleb nevus syndrome medical therapy On the Web |
|
American Roentgen Ray Society Images of Blue rubber bleb nevus syndrome medical therapy |
|
Directions to Hospitals Treating Blue rubber bleb nevus syndrome |
|
Risk calculators and risk factors for Blue rubber bleb nevus syndrome medical therapy |
References
- ↑ Agnese M, Cipolletta L, Bianco MA, Quitadamo P, Miele E, Staiano A (April 2010). "Blue rubber bleb nevus syndrome". Acta Paediatr. 99 (4): 632–5. doi:10.1111/j.1651-2227.2009.01608.x. PMID 19958301.
- ↑ Jain A, Kar P, Chander R, Khandpur S, Jain S, Prabhash K, Gangwal P (1998). "Blue rubber bleb nevus syndrome: a cause of gastrointestinal hemorrhage". Indian J Gastroenterol. 17 (4): 153–4. PMID 9795507.
- ↑ Jin, Xue-Li (2014). "Blue rubber bleb nevus syndrome: A case report and literature review". World Journal of Gastroenterology. 20 (45): 17254. doi:10.3748/wjg.v20.i45.17254. ISSN 1007-9327.
- ↑ Boente, Maria del C.; Cordisco, Maria R.; Frontini, Maria del V.; Asial, Raul A. (1999). "Blue Rubber Bleb Nevus (Bean Syndrome): Evolution of Four Cases and Clinical Response to Pharmacologic Agents". Pediatric Dermatology. 16 (3): 222–227. doi:10.1046/j.1525-1470.1999.00065.x. ISSN 0736-8046.
- ↑ Ogu, Ugochi O.; Abusin, Ghada; Abu-Arja, Rolla F.; Staber, Janice M. (2018). "Successful Management of Blue Rubber Bleb Nevus Syndrome (BRBNS) with Sirolimus". Case Reports in Pediatrics. 2018: 1–5. doi:10.1155/2018/7654278. ISSN 2090-6803.
- ↑ Ünlüsoy Aksu A, Sari S, Eğritaş Gürkan Ö, Dalgiç B (March 2017). "Favorable Response to Sirolimus in a Child With Blue Rubber Bleb Nevus Syndrome in the Gastrointestinal Tract". J. Pediatr. Hematol. Oncol. 39 (2): 147–149. doi:10.1097/MPH.0000000000000681. PMID 27820137.