Rhabdomyosarcoma epidemiology and demographics: Difference between revisions
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*Almost 350 new cases of rhabdomyosarcoma are diagnosed annually.<ref name="pmid27955730" /> | *Almost 350 new cases of rhabdomyosarcoma are diagnosed annually.<ref name="pmid27955730" /> | ||
===Incidence=== | ===Incidence=== | ||
*The incidence of rhabdomyosarcomais about 0.43 in 100,000 annually among children,adolescents, and young adults under 20 years old. | |||
The overall [[incidence]] of rhabdomyosarcoma in children is 0.45 cases for 100,000 children and 50% of cases are seen in the first decade of life.<ref name="NCI">{{cite web | title = Childhood Rhabdomyosarcoma Treatment| url =http://www.cancer.gov/types/soft-tissue-sarcoma/hp/rhabdomyosarcoma-treatment-pdq}}</ref> Incidence may depend on the histologic subtype of rhabdomyosarcoma: | The overall [[incidence]] of rhabdomyosarcoma in children is 0.45 cases for 100,000 children and 50% of cases are seen in the first decade of life.<ref name="NCI">{{cite web | title = Childhood Rhabdomyosarcoma Treatment| url =http://www.cancer.gov/types/soft-tissue-sarcoma/hp/rhabdomyosarcoma-treatment-pdq}}</ref> Incidence may depend on the histologic subtype of rhabdomyosarcoma: | ||
*Embryonal rhabdomyosarcoma: Embryonal rhabdomyosarcoma peaks in 0 to 4 year age group at approximately 0.4 cases per 100,000 children, with a lower rate in adolescents, approximately 0.15 cases per 100,000 adolescents. | *Embryonal rhabdomyosarcoma: Embryonal rhabdomyosarcoma peaks in 0 to 4 year age group at approximately 0.4 cases per 100,000 children, with a lower rate in adolescents, approximately 0.15 cases per 100,000 adolescents. | ||
Revision as of 18:53, 10 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Epidemiology and Demographics
- Rhabdomyosarcoma is considered as a most common soft tissue cancers among children and adolescents and it is the third most common extracranial solid tumors during childhood which comes after neuroblastomaand wilms tumor.[1][2]
- Rhabdomyosarcoma is responsible for 50% of soft tissue tumors during childhood and 5% of all pediatrics cancers.[3]
- Almost 350 new cases of rhabdomyosarcoma are diagnosed annually.[1]
Incidence
- The incidence of rhabdomyosarcomais about 0.43 in 100,000 annually among children,adolescents, and young adults under 20 years old.
The overall incidence of rhabdomyosarcoma in children is 0.45 cases for 100,000 children and 50% of cases are seen in the first decade of life.[4] Incidence may depend on the histologic subtype of rhabdomyosarcoma:
- Embryonal rhabdomyosarcoma: Embryonal rhabdomyosarcoma peaks in 0 to 4 year age group at approximately 0.4 cases per 100,000 children, with a lower rate in adolescents, approximately 0.15 cases per 100,000 adolescents.
- Alveolar rhabdomyosarcoma: The incidence of alveolar rhabdomyosarcoma does not vary by gender and is constant from ages 0 to 19 years at approximately 0.1 case per 100,000 children and adolescents.
- Undifferentiated sarcoma: Infants younger than 1 year have a higher incidence of undifferentiated sarcoma.
Age
In general, rhabdomyosarcoma tends to affect individuals less than 45 years of age.
- Rhabdomyosarcoma is most commonly seen in children aged one to five years old. Overall, 65% of all rhabdomyosarcomas are diagnosed in patients under 10 years old.
- Less commonly, it can also present in teens aged 15 to 19, and can even develop in adulthood, though this is even more rare.
References
- ↑ 1.0 1.1 Dasgupta R, Fuchs J, Rodeberg D (2016). "Rhabdomyosarcoma". Semin Pediatr Surg. 25 (5): 276–283. doi:10.1053/j.sempedsurg.2016.09.011. PMID 27955730.
- ↑ Arndt CA, Crist WM (1999). "Common musculoskeletal tumors of childhood and adolescence". N Engl J Med. 341 (5): 342–52. doi:10.1056/NEJM199907293410507. PMID 10423470.
- ↑ Dasgupta R, Rodeberg DA (2012). "Update on rhabdomyosarcoma". Semin Pediatr Surg. 21 (1): 68–78. doi:10.1053/j.sempedsurg.2011.10.007. PMID 22248972.
- ↑ "Childhood Rhabdomyosarcoma Treatment".