Pseudomyxoma peritonei history and symptoms: Difference between revisions

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Symptoms of pseudomyxoma peritonei include [[abdominal pain]], [[bloating]], [[abdominal distention]], weight changes, and [[infertility]].
Symptoms of pseudomyxoma peritonei include [[abdominal pain]], [[bloating]], [[abdominal distention]], weight changes, and [[infertility]].
==History==
==History==
The median age of diagnosis for pseudomyxoma peritonei is 50 years old,it is usually found incidentally in patients undergoing abdominal surgery or imaging for other medical conditions. Due to its non-specific symptoms, most patients are diagnosed with advanced disease. The clinical presentation of the disease is dependent on the progression of the disease. Tumors that originate in appendix typically presents with appendicitis-like symptoms or a pelvic mass due to mucinous deposits and compression on adjacent organs. More advanced disease can present with abdominal distension, bowel obstruction, and ascites. The classic sign termed “jelly belly” is an increase in abdominal girth caused by an accumulation of gelatinous ascites.<ref name="pmid17511043">{{cite journal |vauthors=Dixit A, Robertson JH, Mudan SS, Akle C |title=Appendiceal mucocoeles and pseudomyxoma peritonei |journal=World J. Gastroenterol. |volume=13 |issue=16 |pages=2381–4 |date=April 2007 |pmid=17511043 |pmc=4147153 |doi= |url=}}</ref><ref name="pmid11044169">{{cite journal |vauthors=Esquivel J, Sugarbaker PH |title=Clinical presentation of the Pseudomyxoma peritonei syndrome |journal=Br J Surg |volume=87 |issue=10 |pages=1414–8 |date=October 2000 |pmid=11044169 |doi=10.1046/j.1365-2168.2000.01553.x |url=}}</ref>
The median age of diagnosis for pseudomyxoma peritonei is 50 years old,it is usually found incidentally in patients undergoing abdominal surgery or imaging for other medical conditions, most patients are diagnosed with advanced disease due to non specific symptoms of pseudomyxoma peritonei. The clinical presentation of the disease is dependent on the progression of the disease. Tumors with appendiceal origintypically presents with appendicitis-like symptoms or if there is ovarian origin,it can present as a pelvic mass due to its compression impact on internal organs. More advanced disease can present with abdominal distension, bowel obstruction, and ascites. The classic sign termed “jelly belly” is an increase in abdominal girth caused by an accumulation of gelatinous ascites.<ref name="pmid17511043">{{cite journal |vauthors=Dixit A, Robertson JH, Mudan SS, Akle C |title=Appendiceal mucocoeles and pseudomyxoma peritonei |journal=World J. Gastroenterol. |volume=13 |issue=16 |pages=2381–4 |date=April 2007 |pmid=17511043 |pmc=4147153 |doi= |url=}}</ref><ref name="pmid11044169">{{cite journal |vauthors=Esquivel J, Sugarbaker PH |title=Clinical presentation of the Pseudomyxoma peritonei syndrome |journal=Br J Surg |volume=87 |issue=10 |pages=1414–8 |date=October 2000 |pmid=11044169 |doi=10.1046/j.1365-2168.2000.01553.x |url=}}</ref><ref name="pmid7750935">{{cite journal |vauthors=Ronnett BM, Kurman RJ, Zahn CM, Shmookler BM, Jablonski KA, Kass ME, Sugarbaker PH |title=Pseudomyxoma peritonei in women: a clinicopathologic analysis of 30 cases with emphasis on site of origin, prognosis, and relationship to ovarian mucinous tumors of low malignant potential |journal=Hum. Pathol. |volume=26 |issue=5 |pages=509–24 |date=May 1995 |pmid=7750935 |doi= |url=}}</ref>


==Symptoms==
==Symptoms==

Revision as of 20:33, 11 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Symptoms of pseudomyxoma peritonei include abdominal pain, bloating, abdominal distention, weight changes, and infertility.

History

The median age of diagnosis for pseudomyxoma peritonei is 50 years old,it is usually found incidentally in patients undergoing abdominal surgery or imaging for other medical conditions, most patients are diagnosed with advanced disease due to non specific symptoms of pseudomyxoma peritonei. The clinical presentation of the disease is dependent on the progression of the disease. Tumors with appendiceal origintypically presents with appendicitis-like symptoms or if there is ovarian origin,it can present as a pelvic mass due to its compression impact on internal organs. More advanced disease can present with abdominal distension, bowel obstruction, and ascites. The classic sign termed “jelly belly” is an increase in abdominal girth caused by an accumulation of gelatinous ascites.[1][2][3]

Symptoms

Symptoms of pseudomyxoma peritonei may include:[2]

  • Abdominal or pelvic pain
  • New-onset hernia[4]
  • Bloating
  • Abdominal distension
  • Weight change
  • Increased abdominal girth.
  • Appendicitis-like symptoms in some cases.[5]
  • Gynecological complaints in females such as menstrual irregularity due to the ovarian deposits of the mucinous tumor.
  • Subcutaneous non tender umbilical nodule have also been reported in rare cases.[6]

References

  1. Dixit A, Robertson JH, Mudan SS, Akle C (April 2007). "Appendiceal mucocoeles and pseudomyxoma peritonei". World J. Gastroenterol. 13 (16): 2381–4. PMC 4147153. PMID 17511043.
  2. 2.0 2.1 Esquivel J, Sugarbaker PH (October 2000). "Clinical presentation of the Pseudomyxoma peritonei syndrome". Br J Surg. 87 (10): 1414–8. doi:10.1046/j.1365-2168.2000.01553.x. PMID 11044169.
  3. Ronnett BM, Kurman RJ, Zahn CM, Shmookler BM, Jablonski KA, Kass ME, Sugarbaker PH (May 1995). "Pseudomyxoma peritonei in women: a clinicopathologic analysis of 30 cases with emphasis on site of origin, prognosis, and relationship to ovarian mucinous tumors of low malignant potential". Hum. Pathol. 26 (5): 509–24. PMID 7750935.
  4. Gomes C, Tenreiro N, Marçal A, Moreira H, Pinto B, Avelar P (July 2018). "Pseudomyxoma peritonei presenting as irreducible epigastric hernia". J Surg Case Rep. 2018 (7): rjy148. doi:10.1093/jscr/rjy148. PMC 6044295. PMID 30026907.
  5. Smeenk RM, Verwaal VJ, Zoetmulder FA (February 2007). "[Pseudomyxoma peritonei; a rare tumour that can be treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy]". Ned Tijdschr Geneeskd (in Dutch; Flemish). 151 (7): 418–23. PMID 17343142.
  6. Srinivasaiah N, Retnasingam G, Kasarneni R, Slater B (June 2009). "Pseudomyxoma peritonei: a rare presentation as an umbilical nodule". Ir J Med Sci. 178 (2): 219–21. doi:10.1007/s11845-008-0118-2. PMID 18224368.


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