Testicular cancer differential diagnosis: Difference between revisions
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| style="background: #DCDCDC; padding: 5px; text-align: center;" rowspan="5" |Germ Cell | | style="background: #DCDCDC; padding: 5px; text-align: center;" rowspan="5" |Germ Cell | ||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Seminoma<ref name="pmid9930796">{{cite journal| author=Miller FH, Whitney WS, Fitzgerald SW, Miller EI| title=Seminomas complicating undescended intraabdominal testes in patients with prior negative findings from surgical exploration. | journal=AJR Am J Roentgenol | year= 1999 | volume= 172 | issue= 2 | pages= 425-8 | pmid=9930796 | doi=10.2214/ajr.172.2.9930796 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9930796 }}</ref> | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Seminoma<ref name="pmid26742998">{{cite journal| author=Siegel RL, Miller KD, Jemal A| title=Cancer statistics, 2016. | journal=CA Cancer J Clin | year= 2016 | volume= 66 | issue= 1 | pages= 7-30 | pmid=26742998 | doi=10.3322/caac.21332 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26742998 }}</ref><ref name="pmid9930796">{{cite journal| author=Miller FH, Whitney WS, Fitzgerald SW, Miller EI| title=Seminomas complicating undescended intraabdominal testes in patients with prior negative findings from surgical exploration. | journal=AJR Am J Roentgenol | year= 1999 | volume= 172 | issue= 2 | pages= 425-8 | pmid=9930796 | doi=10.2214/ajr.172.2.9930796 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9930796 }}</ref> | ||
| style="background: #F5F5F5; padding: 5px;" |Malignant | | style="background: #F5F5F5; padding: 5px;" |Malignant | ||
| style="background: #F5F5F5; padding: 5px;" |Unilateral | | style="background: #F5F5F5; padding: 5px;" |Unilateral | ||
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* Large cells wit watery cytoplasm | * Large cells wit watery cytoplasm | ||
* Fried egg appearance | * Fried egg appearance | ||
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Revision as of 15:43, 23 January 2019
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Testicular cancer Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Testicular cancer differential diagnosis On the Web |
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American Roentgen Ray Society Images of Testicular cancer differential diagnosis |
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Risk calculators and risk factors for Testicular cancer differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
Testicular cancer must be differentiated from epididymitis, hematocele, hydrocele, spermatocele, granulomatous orchitis, and varicocele.
Differentiating Testicular cancer from other Diseases
Testicular cancer must be differentiated from:
| Diseases | Benign/ Malignant | Unilateral/Bilateral | History | Demography | Metastasis | Genetics | Histopathology | Clinical manifestations | Para-clinical findings | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pain | Mass | Physical examination | |||||||||||
| Lab Findings | Imaging | ||||||||||||
| Germ Cell | Seminoma[1][2] | Malignant | Unilateral | History of cryptorchidism
Excellent prognosis |
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Late metastasis | Stains positively for ALP, c-KIT, CD30, EMA, and glycogen |
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Elevated serum placental ALP (PALP) | Ultrasound:
Homogeneous hypoechoic intratesticular mass Cysts and calcificications are uncommon Inhomogenous feature in larger mass |
| Embryonal carcinoma | |||||||||||||
| Yolk sac tumor | |||||||||||||
| Teratoma | |||||||||||||
| Choriocarcinoma | |||||||||||||
| Diseases | Benign/ Malignant | Unilateral/Bilateral | History | Demography | Metastasis | Genetics | Pain | Mass | Physical exam | Lab Findings | Imaging | ||
| Non germ cell | Leydig cell tumor | ||||||||||||
| Sertoli cell tumor | |||||||||||||
| Testicular lymphoma | |||||||||||||
| Carcinoma in situ of the testicle | |||||||||||||
References
- ↑ Siegel RL, Miller KD, Jemal A (2016). "Cancer statistics, 2016". CA Cancer J Clin. 66 (1): 7–30. doi:10.3322/caac.21332. PMID 26742998.
- ↑ Miller FH, Whitney WS, Fitzgerald SW, Miller EI (1999). "Seminomas complicating undescended intraabdominal testes in patients with prior negative findings from surgical exploration". AJR Am J Roentgenol. 172 (2): 425–8. doi:10.2214/ajr.172.2.9930796. PMID 9930796.