Testicular cancer differential diagnosis: Difference between revisions
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| style="background: #F5F5F5; padding: 5px;" |Malignant | | style="background: #F5F5F5; padding: 5px;" |Malignant | ||
| style="background: #F5F5F5; padding: 5px;" |Unilateral | | style="background: #F5F5F5; padding: 5px;" |Unilateral | ||
| style="background: #F5F5F5; padding: 5px;" |History of cryptorchidism | | style="background: #F5F5F5; padding: 5px;" | | ||
* History of cryptorchidism | |||
Excellent prognosis | * Excellent prognosis | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
* Most common among age of 15-35 years old | * Most common among age of 15-35 years old | ||
* Does not occur during infancy | * Does not occur during infancy | ||
| style="background: #F5F5F5; padding: 5px;" |Late metastasis | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" |Stains positively for ALP | * Late metastasis | ||
| style="background: #F5F5F5; padding: 5px;" |Stains positively for: | |||
* ALP | |||
* C-KIT | |||
* CD30 | |||
* EMA | |||
* Glycogen | |||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
* Large cells wit watery cytoplasm | * Large cells wit watery cytoplasm | ||
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* Palpable, nontender unilateral testicular mass | * Palpable, nontender unilateral testicular mass | ||
* Usually homogeneous enlargement | * Usually homogeneous enlargement | ||
| style="background: #F5F5F5; padding: 5px;" |Elevated serum placental ALP (PALP) | | style="background: #F5F5F5; padding: 5px;" | | ||
* Elevated serum placental ALP (PALP) | |||
| style="background: #F5F5F5; padding: 5px;" |Ultrasound: | | style="background: #F5F5F5; padding: 5px;" |Ultrasound: | ||
* Homogeneous hypoechoic intratesticular mass | |||
Homogeneous hypoechoic intratesticular mass | * Cysts and calcificications are uncommon | ||
* Inhomogenous feature in larger mass | |||
Cysts and calcificications are uncommon | |||
Inhomogenous feature in larger mass | |||
|- | |- | ||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | Embryonal carcinoma | | style="background: #DCDCDC; padding: 5px; text-align: center;" | Embryonal carcinoma | ||
Revision as of 15:53, 23 January 2019
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Testicular cancer Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Testicular cancer differential diagnosis On the Web |
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American Roentgen Ray Society Images of Testicular cancer differential diagnosis |
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Risk calculators and risk factors for Testicular cancer differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
Testicular cancer must be differentiated from epididymitis, hematocele, hydrocele, spermatocele, granulomatous orchitis, and varicocele.
Differentiating Testicular cancer from other Diseases
Testicular cancer must be differentiated from:
| Diseases | Benign/ Malignant | Unilateral/Bilateral | History | Demography | Metastasis | Genetics | Histopathology | Clinical manifestations | Para-clinical findings | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pain | Mass | Physical examination | |||||||||||
| Lab Findings | Imaging | ||||||||||||
| Germ Cell | Seminoma[1][2] | Malignant | Unilateral |
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Stains positively for:
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- | + |
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Ultrasound:
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| Embryonal carcinoma | |||||||||||||
| Yolk sac tumor | |||||||||||||
| Teratoma | |||||||||||||
| Choriocarcinoma | |||||||||||||
| Diseases | Benign/ Malignant | Unilateral/Bilateral | History | Demography | Metastasis | Genetics | Histopathology | Pain | Mass | Physical exam | Lab Findings | Imaging | |
| Non germ cell | Leydig cell tumor | ||||||||||||
| Sertoli cell tumor | |||||||||||||
| Testicular lymphoma | |||||||||||||
| Carcinoma in situ of the testicle | |||||||||||||
References
- ↑ Siegel RL, Miller KD, Jemal A (2016). "Cancer statistics, 2016". CA Cancer J Clin. 66 (1): 7–30. doi:10.3322/caac.21332. PMID 26742998.
- ↑ Miller FH, Whitney WS, Fitzgerald SW, Miller EI (1999). "Seminomas complicating undescended intraabdominal testes in patients with prior negative findings from surgical exploration". AJR Am J Roentgenol. 172 (2): 425–8. doi:10.2214/ajr.172.2.9930796. PMID 9930796.