Folate deficiency screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Screening for Folate deficiency anemia is usually not routinely recommended for asymptomatic patients.

Screening

• Screening for Folate deficiency anemia is usually not routinely recommended for asymptomatic patients.
• Screening is only recommended for patients with abnormal complete blood count and increased risk of having folate deficiency such as:
  • Older people (Age >65)
  • Alcohol abusers
  • Pregnant or lactating women especially in case of previous history of child with neural tube defect
  • Preterm infants
  • Lower socioeconomic groups
  • History of malabsorption
  • Infants on goats' milk
  • Chronic dialysis patients
• Screening evaluation include measurement of :
  • Complete blood count showing MCV > 100fL with or without low hemoglobin.
  • Fasting serum folate level (Adults: 2-20 ng/mL).