Lymphadenopathy causes: Difference between revisions
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*[[Adult T cell leukemia]] | *[[Adult T cell leukemia]] | ||
*[[African Sleeping sickness]]<ref name="pmid21901632">{{cite journal | | *[[African Sleeping sickness]]<ref name="pmid21901632">{{cite journal |vauthors=Blum JA, Neumayr AL, Hatz CF |title=Human African trypanosomiasis in endemic populations and travellers |journal=Eur. J. Clin. Microbiol. Infect. Dis. |volume=31 |issue=6 |pages=905–13 |date=June 2012 |pmid=21901632 |doi=10.1007/s10096-011-1403-y |url=}}</ref> | ||
*[[AIDS]]<ref name="pmid22716315">{{cite journal |vauthors=Beukes CA, Thiart J |title=The incidence of human herpes virus-8 expression in lymph node biopsies from human immunodeficiency virus-positive patients |journal=Histopathology |volume=61 |issue=5 |pages=942–4 |date=November 2012 |pmid=22716315 |doi=10.1111/j.1365-2559.2012.04291.x |url=}}</ref> | *[[AIDS]]<ref name="pmid22716315">{{cite journal |vauthors=Beukes CA, Thiart J |title=The incidence of human herpes virus-8 expression in lymph node biopsies from human immunodeficiency virus-positive patients |journal=Histopathology |volume=61 |issue=5 |pages=942–4 |date=November 2012 |pmid=22716315 |doi=10.1111/j.1365-2559.2012.04291.x |url=}}</ref> | ||
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*[[Castleman's disease]]<ref name="pmid22791417">{{cite journal |vauthors=Dispenzieri A, Armitage JO, Loe MJ, Geyer SM, Allred J, Camoriano JK, Menke DM, Weisenburger DD, Ristow K, Dogan A, Habermann TM |title=The clinical spectrum of Castleman's disease |journal=Am. J. Hematol. |volume=87 |issue=11 |pages=997–1002 |date=November 2012 |pmid=22791417 |pmc=3900496 |doi=10.1002/ajh.23291 |url=}}</ref> | *[[Castleman's disease]]<ref name="pmid22791417">{{cite journal |vauthors=Dispenzieri A, Armitage JO, Loe MJ, Geyer SM, Allred J, Camoriano JK, Menke DM, Weisenburger DD, Ristow K, Dogan A, Habermann TM |title=The clinical spectrum of Castleman's disease |journal=Am. J. Hematol. |volume=87 |issue=11 |pages=997–1002 |date=November 2012 |pmid=22791417 |pmc=3900496 |doi=10.1002/ajh.23291 |url=}}</ref> | ||
*[[Cat scratch disease]<ref name="pmid22358366">{{cite journal |vauthors=Chondrogiannis K, Vezakis A, Derpapas M, Melemeni A, Fragulidis G |title=Seronegative cat-scratch disease diagnosed by PCR detection of Bartonella henselae DNA in lymph node samples |journal=Braz J Infect Dis |volume=16 |issue=1 |pages=96–9 |date=2012 |pmid=22358366 |doi= |url=}}</ref> | *[[Cat scratch disease]]<ref name="pmid22358366">{{cite journal |vauthors=Chondrogiannis K, Vezakis A, Derpapas M, Melemeni A, Fragulidis G |title=Seronegative cat-scratch disease diagnosed by PCR detection of Bartonella henselae DNA in lymph node samples |journal=Braz J Infect Dis |volume=16 |issue=1 |pages=96–9 |date=2012 |pmid=22358366 |doi= |url=}}</ref> | ||
* [[Certolizumab pegol]] | *[[Certolizumab pegol]] | ||
*[[Chagas' disease]] | *[[Chagas' disease]] | ||
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*[[Familial alphalipoprotein deficiency]] | *[[Familial alphalipoprotein deficiency]] | ||
*[[Familial hemophagocytic lymphohistiocytosis]]<ref name="pmid9094188">{{cite journal | | *[[Familial hemophagocytic lymphohistiocytosis]]<ref name="pmid9094188">{{cite journal |vauthors=Caballes RL, Caballes-Ponce MG, Kim DU |title=Familial hemophagocytic lymphohistiocytosis (FHLH) |journal=Pathology |volume=29 |issue=1 |pages=92–5 |date=February 1997 |pmid=9094188 |doi= |url=}}</ref> | ||
*[[Familial histiocytic reticulosis]]<ref>[http://www.histio.org/site/c.kiKTL4PQLvF/b.1810505/k.F16D/Disease_Information.htmDisease information] at the Histiocytosis Association of America</ref> | *[[Familial histiocytic reticulosis]]<ref>[http://www.histio.org/site/c.kiKTL4PQLvF/b.1810505/k.F16D/Disease_Information.htmDisease information] at the Histiocytosis Association of America</ref> | ||
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*[[Fungal blastomycosis]] | *[[Fungal blastomycosis]] | ||
*[[Gamma heavy chain disease]]<ref name="pmid22301495">{{cite journal | | *[[Gamma heavy chain disease]]<ref name="pmid22301495">{{cite journal |vauthors=Bieliauskas S, Tubbs RR, Bacon CM, Eshoa C, Foucar K, Gibson SE, Kroft SH, Sohani AR, Swerdlow SH, Cook JR |title=Gamma heavy-chain disease: defining the spectrum of associated lymphoproliferative disorders through analysis of 13 cases |journal=Am. J. Surg. Pathol. |volume=36 |issue=4 |pages=534–43 |date=April 2012 |pmid=22301495 |pmc=3715127 |doi=10.1097/PAS.0b013e318240590a |url=}}</ref> | ||
*[[German Measles]] | *[[German Measles]] | ||
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*[[Granuloma inguinale]] | *[[Granuloma inguinale]] | ||
*[[Griscelli disease]]<ref name="pmid22223973">{{cite journal | | *[[Griscelli disease]]<ref name="pmid22223973">{{cite journal |vauthors=Reddy RR, Babu BM, Venkateshwaramma B, Hymavathi Ch |title=Silvery hair syndrome in two cousins: Chediak-Higashi syndrome vs Griscelli syndrome, with rare associations |journal=Int J Trichology |volume=3 |issue=2 |pages=107–11 |date=July 2011 |pmid=22223973 |pmc=3250006 |doi=10.4103/0974-7753.90825 |url=}}</ref> | ||
*[[Hairy cell leukaemia]] | *[[Hairy cell leukaemia]] | ||
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{{ColBreak}} | {{ColBreak}} | ||
*[[Hemangiopericytoma]]<ref name="pmid21345688">{{cite journal | | *[[Hemangiopericytoma]]<ref name="pmid21345688">{{cite journal |vauthors=Vilendecic M, Grahovac G, Lambasa S, Jelec V, Topic I |title=Unrecognized hemangiopericytoma of posterior cervical region with intracranial extension |journal=J Craniomaxillofac Surg |volume=40 |issue=2 |pages=e51–3 |date=February 2012 |pmid=21345688 |doi=10.1016/j.jcms.2011.01.019 |url=}}</ref> | ||
*Hemoblastosis<ref name="pmid18494289">{{cite journal |author=Pospelova TI, Koptev VD, Volkova II, Loseva MI, Ageeva TA, Soldatova GS |title=[The stage of portal blood flow in patients with hemoblastosis combined with chronic hepatitis] |language=Russian |journal=Klin Med (Mosk) |volume=86 |issue=4 |pages=55–8 |year=2008 |pmid=18494289 |doi= |url=}}</ref> | *Hemoblastosis<ref name="pmid18494289">{{cite journal |author=Pospelova TI, Koptev VD, Volkova II, Loseva MI, Ageeva TA, Soldatova GS |title=[The stage of portal blood flow in patients with hemoblastosis combined with chronic hepatitis] |language=Russian |journal=Klin Med (Mosk) |volume=86 |issue=4 |pages=55–8 |year=2008 |pmid=18494289 |doi= |url=}}</ref> | ||
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*[[Herpes simplex]] | *[[Herpes simplex]] | ||
*[[Histiocytosis X]]<ref name="pmid22835048">{{cite journal | | *[[Histiocytosis X]]<ref name="pmid22835048">{{cite journal |vauthors=Edelbroek JR, Vermeer MH, Jansen PM, Stoof TJ, van der Linden MM, Horváth B, van Baarlen J, Willemze R |title=Langerhans cell histiocytosis first presenting in the skin in adults: frequent association with a second haematological malignancy |journal=Br. J. Dermatol. |volume=167 |issue=6 |pages=1287–94 |date=December 2012 |pmid=22835048 |doi=10.1111/j.1365-2133.2012.11169.x |url=}}</ref> | ||
*[[Histoplasmosis]] | *[[Histoplasmosis]] | ||
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*[[Lymphatic filariasis]] | *[[Lymphatic filariasis]] | ||
*[[Lymphogranuloma venereum]]<ref name="pmid22783058">{{cite journal | | *[[Lymphogranuloma venereum]]<ref name="pmid22783058">{{cite journal |vauthors=Gallegos M, Bradly D, Jakate S, Keshavarzian A |title=Lymphogranuloma venereum proctosigmoiditis is a mimicker of inflammatory bowel disease |journal=World J. Gastroenterol. |volume=18 |issue=25 |pages=3317–21 |date=July 2012 |pmid=22783058 |doi=10.3748/wjg.v18.i25.3317 |url=}}</ref> | ||
*[[Lymphoma]] | *[[Lymphoma]] | ||
*[[Macroglobulinemia]]<ref name="pmid22773606">{{cite journal | | *[[Macroglobulinemia]]<ref name="pmid22773606">{{cite journal |vauthors=Braggio E, Philipsborn C, Novak A, Hodge L, Ansell S, Fonseca R |title=Molecular pathogenesis of Waldenstrom's macroglobulinemia |journal=Haematologica |volume=97 |issue=9 |pages=1281–90 |date=September 2012 |pmid=22773606 |pmc=3436227 |doi=10.3324/haematol.2012.068478 |url=}}</ref> | ||
*[[Malignant lymphoma]] | *[[Malignant lymphoma]] | ||
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*[[Mumps]] | *[[Mumps]] | ||
*[[Mycobacterium avium-intracellulare]]<ref name="pmid22833551">{{cite journal | | *[[Mycobacterium avium-intracellulare]]<ref name="pmid22833551">{{cite journal |vauthors=Do PC, Nussbaum E, Moua J, Chin T, Randhawa I |title=Clinical significance of respiratory isolates for Mycobacterium abscessus complex from pediatric patients |journal=Pediatr. Pulmonol. |volume=48 |issue=5 |pages=470–80 |date=May 2013 |pmid=22833551 |doi=10.1002/ppul.22638 |url=}}</ref> | ||
*[[Mycobacterium chelonae]] | *[[Mycobacterium chelonae]] | ||
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*[[Siccardi syndrome]] | *[[Siccardi syndrome]] | ||
*[[Sinus histiocytosis]]<ref name="pmid11835335">{{cite journal | | *[[Sinus histiocytosis]]<ref name="pmid11835335">{{cite journal |vauthors=Pulsoni A, Anghel G, Falcucci P, Matera R, Pescarmona E, Ribersani M, Villivà N, Mandelli F |title=Treatment of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): report of a case and literature review |journal=Am. J. Hematol. |volume=69 |issue=1 |pages=67–71 |date=January 2002 |pmid=11835335 |doi= |url=}}</ref> | ||
*[[SLE]] | *[[SLE]] | ||
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*[[Systemic mastocytosis]] | *[[Systemic mastocytosis]] | ||
*[[Tang Hsi Ryu syndrome]]<ref name="pmid6663309">{{cite journal | | *[[Tang Hsi Ryu syndrome]]<ref name="pmid6663309">{{cite journal |vauthors=Tang LM, Hsi MS, Ryu SJ, Minauchi Y |title=Syndrome of polyneuropathy, skin hyperpigmentation, oedema and hepatosplenomegaly |journal=J. Neurol. Neurosurg. Psychiatry |volume=46 |issue=12 |pages=1108–14 |date=December 1983 |pmid=6663309 |pmc=491776 |doi= |url=}}</ref> | ||
*[[Three-day fever]]<ref name="pmid20304745">{{cite journal | | *[[Three-day fever]]<ref name="pmid20304745">{{cite journal |vauthors=Ongrádi J, Kövesdi V, Medveczky GP |title=[Human herpesvirus 6] |language=Hungarian |journal=Orv Hetil |volume=151 |issue=13 |pages=523–32 |date=March 2010 |pmid=20304745 |doi=10.1556/OH.2010.28848 |url=}}</ref> | ||
*[[Tiagabine]] | *[[Tiagabine]] |
Revision as of 17:17, 29 January 2019
Lymphadenopathy Microchapters |
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Lymphadenopathy causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]Raviteja Guddeti, M.B.B.S. [3]
Overview
The most common causes of lymphadenopathy include infections, cancers and connective tissue disorders.
Causes
Common Causes
Common causes of lymphadenopathy may include:
- Acute infections (e.g. bacterial, or viral)
- Chronic infections:
- tuberculous lymphadenitis,
- cat-scratch disease
- AIDS - generalized lymphadenopathy[1]
- Toxoplasmosis, a parasitic disease, gives a generalized lymphadenopathy[2]
- Cancers:[2]
- Hodgkin lymphoma
- non-Hodgkin lymphoma,
- hairy cell leukemia, ( all or a few lymph nodes )
- Metastasis
- Connective tissue disorders:
Causes by Organ System
- Infections (acute suppurative)
- Fungal
- Mycobacterial
- Viral
- Protozoal (e.g. toxoplasma)
- Bacterial (e.g. chlamydia, rickettsia, bartonella)
- Reactive
- Follicular hyperplasia
- Paracortical hyperplasia
- Sinus histiocytosis
- Granulomatous
- Neoplastic
- Drugs (e.g. cyclosporin, phenytoin, methotrexate)
- Lipid storage diseases
- IgG4-related sclerosing disease
Causes in Alphabetical Order
Various causes in alphabetical order:[5][6]
|
|
|
Bihilar Lymphadenopathy
- The common causes can divide into the following:
- Tuberculosis
- Sarcoidosis
- Lymphoma
- Other malignancies
- Less common causes include:
References
- ↑ Chris Jennings (1993). "Understanding and Preventing AIDS: A Book for Everyone".
- ↑ 2.0 2.1 Status and anamnesis, Anders Albinsson. Page 12
- ↑ Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A (2014). "Peripheral lymphadenopathy: approach and diagnostic tools". Iran J Med Sci. 39 (2 Suppl): 158–70. PMC 3993046. PMID 24753638.
- ↑ Lymph node enlargment. Wikipedia. https://en.wikipedia.org/wiki/Lymph_node Accessed on May 9, 2016
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
- ↑ Blum JA, Neumayr AL, Hatz CF (June 2012). "Human African trypanosomiasis in endemic populations and travellers". Eur. J. Clin. Microbiol. Infect. Dis. 31 (6): 905–13. doi:10.1007/s10096-011-1403-y. PMID 21901632.
- ↑ Beukes CA, Thiart J (November 2012). "The incidence of human herpes virus-8 expression in lymph node biopsies from human immunodeficiency virus-positive patients". Histopathology. 61 (5): 942–4. doi:10.1111/j.1365-2559.2012.04291.x. PMID 22716315.
- ↑ Mitsuhashi K, Shiseki M, Ishiyama M, Kondo T, Kazama H, Yasunami T, Okamura T, Yoshinaga K, Mori N, Teramura M, Masuda A, Motoji T (July 2011). "[Angioimmunoblastic T-cell lymphoma with marked polyclonal plasmacytosis in peripheral blood and bone marrow mimicking plasma cell leukemia]". Rinsho Ketsueki (in Japanese). 52 (7): 563–9. PMID 21821991.
- ↑ Simonelli S, Gianazza E, Mombelli G, Bondioli A, Ferraro G, Penco S, Sirtori CR, Franceschini G, Calabresi L (January 2012). "Severe high-density lipoprotein deficiency associated with autoantibodies against lecithin:cholesterol acyltransferase in non-Hodgkin lymphoma". Arch. Intern. Med. 172 (2): 179–81. doi:10.1001/archinternmed.2011.661. PMID 22271127.
- ↑ Simesen de Bielke MG, Yancoski J, Rocco C, Pérez LE, Cantisano C, Pérez N, Oleastro M, Danielian S (December 2012). "A missense mutation in the extracellular domain of Fas: the most common change in Argentinean patients with autoimmune lymphoproliferative syndrome represents a founder effect". J. Clin. Immunol. 32 (6): 1197–203. doi:10.1007/s10875-012-9731-y. PMID 22752343.
- ↑ Schleenvoigt BT, Keller P, Stallmach A, Pletz MW (April 2012). "[African tick bite fever--rickettsiosis after holiday in South Africa]". Dtsch. Med. Wochenschr. (in German). 137 (17): 891–3. doi:10.1055/s-0032-1304902. PMID 22511280.
- ↑ Roushan MR, Amiri MJ (April 2013). "Update on childhood brucellosis". Recent Pat Antiinfect Drug Discov. 8 (1): 42–6. PMID 22812616.
- ↑ Dispenzieri A, Armitage JO, Loe MJ, Geyer SM, Allred J, Camoriano JK, Menke DM, Weisenburger DD, Ristow K, Dogan A, Habermann TM (November 2012). "The clinical spectrum of Castleman's disease". Am. J. Hematol. 87 (11): 997–1002. doi:10.1002/ajh.23291. PMC 3900496. PMID 22791417.
- ↑ Chondrogiannis K, Vezakis A, Derpapas M, Melemeni A, Fragulidis G (2012). "Seronegative cat-scratch disease diagnosed by PCR detection of Bartonella henselae DNA in lymph node samples". Braz J Infect Dis. 16 (1): 96–9. PMID 22358366.
- ↑ 16.0 16.1 Reddy RR, Babu BM, Venkateshwaramma B, Hymavathi C (July 2011). "Silvery hair syndrome in two cousins: Chediak-Higashi syndrome vs Griscelli syndrome, with rare associations". Int J Trichology. 3 (2): 107–11. doi:10.4103/0974-7753.90825. PMC 3250006. PMID 22223973. Vancouver style error: initials (help)
- ↑ Fantinato GT, Cestari Sda C, Afonso JP, Sousa LS, Enokihara MM (2011). "Do you know this syndrome? Chediak-Higashi syndrome". An Bras Dermatol. 86 (5): 1029. PMID 22147054.
- ↑ Warnatz K, Voll RE (2012). "Pathogenesis of autoimmunity in common variable immunodeficiency". Front Immunol. 3: 210. doi:10.3389/fimmu.2012.00210. PMC 3399211. PMID 22826712.
- ↑ 19.0 19.1 Goyal T, Varshney A (May 2012). "A rare presentation of erythrodermic mycosis fungoides". Cutis. 89 (5): 229–32, 236. PMID 22768436.
- ↑ Caballes RL, Caballes-Ponce MG, Kim DU (February 1997). "Familial hemophagocytic lymphohistiocytosis (FHLH)". Pathology. 29 (1): 92–5. PMID 9094188.
- ↑ information at the Histiocytosis Association of America
- ↑ Bieliauskas S, Tubbs RR, Bacon CM, Eshoa C, Foucar K, Gibson SE, Kroft SH, Sohani AR, Swerdlow SH, Cook JR (April 2012). "Gamma heavy-chain disease: defining the spectrum of associated lymphoproliferative disorders through analysis of 13 cases". Am. J. Surg. Pathol. 36 (4): 534–43. doi:10.1097/PAS.0b013e318240590a. PMC 3715127. PMID 22301495.
- ↑ Vilendecic M, Grahovac G, Lambasa S, Jelec V, Topic I (February 2012). "Unrecognized hemangiopericytoma of posterior cervical region with intracranial extension". J Craniomaxillofac Surg. 40 (2): e51–3. doi:10.1016/j.jcms.2011.01.019. PMID 21345688.
- ↑ Pospelova TI, Koptev VD, Volkova II, Loseva MI, Ageeva TA, Soldatova GS (2008). "[The stage of portal blood flow in patients with hemoblastosis combined with chronic hepatitis]". Klin Med (Mosk) (in Russian). 86 (4): 55–8. PMID 18494289.
- ↑ Edelbroek JR, Vermeer MH, Jansen PM, Stoof TJ, van der Linden MM, Horváth B, van Baarlen J, Willemze R (December 2012). "Langerhans cell histiocytosis first presenting in the skin in adults: frequent association with a second haematological malignancy". Br. J. Dermatol. 167 (6): 1287–94. doi:10.1111/j.1365-2133.2012.11169.x. PMID 22835048.
- ↑ Bennett L. Listeria monocytogenes. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2009:chap 207
- ↑ Gallegos M, Bradly D, Jakate S, Keshavarzian A (July 2012). "Lymphogranuloma venereum proctosigmoiditis is a mimicker of inflammatory bowel disease". World J. Gastroenterol. 18 (25): 3317–21. doi:10.3748/wjg.v18.i25.3317. PMID 22783058.
- ↑ 28.0 28.1 Braggio E, Philipsborn C, Novak A, Hodge L, Ansell S, Fonseca R (September 2012). "Molecular pathogenesis of Waldenstrom's macroglobulinemia". Haematologica. 97 (9): 1281–90. doi:10.3324/haematol.2012.068478. PMC 3436227. PMID 22773606.
- ↑ Do PC, Nussbaum E, Moua J, Chin T, Randhawa I (May 2013). "Clinical significance of respiratory isolates for Mycobacterium abscessus complex from pediatric patients". Pediatr. Pulmonol. 48 (5): 470–80. doi:10.1002/ppul.22638. PMID 22833551.
- ↑ Pulsoni A, Anghel G, Falcucci P, Matera R, Pescarmona E, Ribersani M, Villivà N, Mandelli F (January 2002). "Treatment of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): report of a case and literature review". Am. J. Hematol. 69 (1): 67–71. PMID 11835335.
- ↑ NP-C Guidelines Working Group, Wraith JE, Baumgartner MR, Bembi B, Covanis A, Levade T, Mengel E, et al. Recommendations on the diagnosis and management of Niemann-Pick disease type C. Mol Genet Metab. 2009;98:152-165
- ↑ Tang LM, Hsi MS, Ryu SJ, Minauchi Y (December 1983). "Syndrome of polyneuropathy, skin hyperpigmentation, oedema and hepatosplenomegaly". J. Neurol. Neurosurg. Psychiatry. 46 (12): 1108–14. PMC 491776. PMID 6663309.
- ↑ Ongrádi J, Kövesdi V, Medveczky GP (March 2010). "[Human herpesvirus 6]". Orv Hetil (in Hungarian). 151 (13): 523–32. doi:10.1556/OH.2010.28848. PMID 20304745.