Endometrial cancer differential diagnosis: Difference between revisions

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Revision as of 19:29, 29 January 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]Roukoz A. Karam, M.D.[3]

Overview

In early stages endometrial cancer must be differentiated from diseases that cause abnormal uterine bleeding and endometrial thickening on ultrasound, such as endometrial hyperplasia, endometrial polyp and submucosal uterine leiomyoma. In advanced stages endometrial cancer must be differentiated from uterine sarcoma and uterine lymphoma.

Differentiating Endometrial Cancer From Other Diseases

In early disease, uterine cancer must be differentiated from other diseases causing endometrial thickening:^[1]

Benign endometrial proliferation
Endometrial hyperplasia
Endometrial polyp
Submucosal uterine leiomyoma

In advanced disease, uterine cancer must be differentiated from other diseases:^[1]

Uterine sarcoma

Endometrial stromal sarcoma (ESS)
Leiomyosarcoma of the uterus
Malignant mixed Mullerian tumour (MMMT) of the uterus

Uterine lymphoma: rare

Primary uterine lymphoma
Secondary uterine involvement with lymphoma

Cervical cancer with uterine invasion
Metastasis to the uterus from a non gynecological malignancy: rare

	Symptoms				Physical examination		Lab Findings		Imaging
Diseases	Clinical manifestations						Para-clinical findings				Pap Smear	Histopathology	Gold standard	Additional findings
	Symptoms				Physical examination		Para-clinical findings
	Vaginal leeding	Pelvic Pain	Pelvic Pressure	Abdominal Distention	Pelvic Mass	Abdominal Distension	Hb	CEA-19	Ultrasound	MRI
Uterine cancer
Uterine sarcoma
Uterine lymphoma
Uterine leiomyoma
Malignant mixedMullerian tumour (MMMT) of the uterus
Cervical cancerwith uterine invasion
Metastasis to the uterusfrom a non gynaecologcial malignancy
Endometrial polyp
Endometrial hyperplasia
Fetus
Uterine adenomyoma
Hematometra

References

↑ ^1.0 ^1.1 Hippisley-Cox J, Coupland C (2011). "Identifying women with suspected ovarian cancer in primary care: derivation and validation of algorithm". BMJ. 344: d8009. doi:10.1136/bmj.d8009. PMC 3251328. PMID 22217630.

Template:WikiDoc Sources

[pmid22217630-1] 1.0 ^1.1 Hippisley-Cox J, Coupland C (2011). "Identifying women with suspected ovarian cancer in primary care: derivation and validation of algorithm". BMJ. 344: d8009. doi:10.1136/bmj.d8009. PMC 3251328. PMID 22217630.

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Endometrial cancer differential diagnosis: Difference between revisions

Revision as of 19:29, 29 January 2019

Overview

Differentiating Endometrial Cancer From Other Diseases

References

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