Rhabdomyosarcoma other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
Biopsy considered as the most commonly diagnostic study in rhabdomyosarcoma and it can be done by open surery, core-needle biopsy, and fine-needle biopsy. Lumbar puncture is an another diagnostic study in parameningeal rhabdomyosarcoma and meningeal involvement cases. Bone marrow aspiration and biopsy are usually performed evaluation of bone marrow involvement due to metastases. | |||
==Other Diagnostic Tests== | ==Other Diagnostic Tests== | ||
===Biopsy=== | ===Biopsy=== | ||
* Tissue biopsy considered as most commonly | * Tissue biopsy considered as most commonly diagnostic study in rhabdomyosarcoma.<ref name="pmid19418540">{{cite journal| author=Chowdhury T, Barnacle A, Haque S, Sebire N, Gibson S, Anderson J et al.| title=Ultrasound-guided core needle biopsy for the diagnosis of rhabdomyosarcoma in childhood. | journal=Pediatr Blood Cancer | year= 2009 | volume= 53 | issue= 3 | pages= 356-60 | pmid=19418540 | doi=10.1002/pbc.22059 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19418540 }} </ref> | ||
* There are several ways of taking biopsies which depends on following criteria:<ref name="pmid24599626">{{cite journal| author=Nunez AL, Elgin JN, Fatima H| title=Fine-needle aspiration biopsy of alveolar rhabdomyosarcoma of Stensen's duct: a case report and review of the literature. | journal=Diagn Cytopathol | year= 2014 | volume= 42 | issue= 12 | pages= 1069-74 | pmid=24599626 | doi=10.1002/dc.23084 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24599626 }} </ref><ref name=":0">Kaseb H, Babiker HM. Cancer, Rhabdomyosarcoma. [Updated 2018 Oct 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507721/</ref> | * There are several ways of taking biopsies which depends on following criteria:<ref name="pmid24599626">{{cite journal| author=Nunez AL, Elgin JN, Fatima H| title=Fine-needle aspiration biopsy of alveolar rhabdomyosarcoma of Stensen's duct: a case report and review of the literature. | journal=Diagn Cytopathol | year= 2014 | volume= 42 | issue= 12 | pages= 1069-74 | pmid=24599626 | doi=10.1002/dc.23084 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24599626 }} </ref><ref name=":0">Kaseb H, Babiker HM. Cancer, Rhabdomyosarcoma. [Updated 2018 Oct 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507721/</ref> | ||
** Patients's age | ** Patients's age | ||
Revision as of 16:57, 8 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
Biopsy considered as the most commonly diagnostic study in rhabdomyosarcoma and it can be done by open surery, core-needle biopsy, and fine-needle biopsy. Lumbar puncture is an another diagnostic study in parameningeal rhabdomyosarcoma and meningeal involvement cases. Bone marrow aspiration and biopsy are usually performed evaluation of bone marrow involvement due to metastases.
Other Diagnostic Tests
Biopsy
- Tissue biopsy considered as most commonly diagnostic study in rhabdomyosarcoma.[1]
- There are several ways of taking biopsies which depends on following criteria:[2][3]
- Patients's age
- Primary site of tumor
- Open surgical biopsy is considered as a recommended method to obtaining tissues and proper diagnosis.[4]
- Needle biopsies are considered as less invasive way of taking biopsies.
- Core-needle biopsy
- Fine- needle biopsy
Lumbar puncture
- Lumbar puncture is considered as unnecessary procedure in rhabdomyosarcoma diagnosis.[5]
- Lumbar puncture is usually done in parameningeal rhabdomyosarcoma.
- Also may be considered as a diagnostic study in rhabdomyosarcomas with meningeal involvement.
Bone marrow aspiration and biopsy
- Bone marrow aspiration is usually performed for evaluation of bone marrow involvement due to metastases.[3][5]
- The samples are taken from pelvic bones.
- It is considered as low yield diagnostic study.
References
- ↑ Chowdhury T, Barnacle A, Haque S, Sebire N, Gibson S, Anderson J; et al. (2009). "Ultrasound-guided core needle biopsy for the diagnosis of rhabdomyosarcoma in childhood". Pediatr Blood Cancer. 53 (3): 356–60. doi:10.1002/pbc.22059. PMID 19418540.
- ↑ Nunez AL, Elgin JN, Fatima H (2014). "Fine-needle aspiration biopsy of alveolar rhabdomyosarcoma of Stensen's duct: a case report and review of the literature". Diagn Cytopathol. 42 (12): 1069–74. doi:10.1002/dc.23084. PMID 24599626.
- ↑ 3.0 3.1 Kaseb H, Babiker HM. Cancer, Rhabdomyosarcoma. [Updated 2018 Oct 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507721/
- ↑ PDQ Pediatric Treatment Editorial Board. Childhood Rhabdomyosarcoma Treatment (PDQ®): Patient Version. 2019 Jan 30. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK65839/
- ↑ 5.0 5.1 Weiss AR, Lyden ER, Anderson JR, Hawkins DS, Spunt SL, Walterhouse DO; et al. (2013). "Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee". J Clin Oncol. 31 (26): 3226–32. doi:10.1200/JCO.2012.44.6476. PMC 3757291. PMID 23940218.