Lung cancer classification

Lung cancer Microchapters
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Epithelial tumors

• Adenocarcinoma
  • Lepidic adenocarcinoma
  • Acinar adenocarcinoma
  • Papillary adenocarcinoma
  • Micropapillary adenocarcinoma
  • Solid adenocarcinoma
  • Invasive mucinous adenocarcinoma
    • Mixed invasive mucinous
    • Nonmucinous adenocarcinoma
  • Colloid adenocarcinoma
  • Fetal adenocarcinoma
  • Enteric adenocarcinoma
  • Minimally invasive adenocarcinoma
  • Nonmucinous
    • Mucinous
  • Preinvasive lesions
    • Atypical adenomatous hyperplasia
    • Adenocarcinoma in situ
      • Nonmucinous
      • Mucinous

• Squamous cell carcinoma
  • Keratinizing squamous cell carcinoma
  • Nonkeratinizing squamous cell carcinoma
  • Basaloid squamous cell carcinoma
  • Preinvasive lesion
    • Squamous cell carcinoma in situ

Neuroendocrine tumors

• Small cell carcinoma
  • Combined small cell carcinoma
• Large cell neuroendocrine carcinoma
  • Combined large cell neuroendocrine carcinoma
• Carcinoid tumors
  • Typical carcinoid tumor
  • Atypical carcinoid tumor
• Preinvasive lesion
  • Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia
• Large cell carcinoma
• Adenosquamous carcinoma
• Sarcomatoid carcinomas
  • Pleomorphic carcinoma
  • Spindle cell carcinoma
  • Giant cell carcinoma
  • Carcinosarcoma
  • Pulmonary blastoma
• Other and Unclassified carcinomas
  • Lymphoepithelioma-like carcinoma
  • NUT carcinoma
• Salivary gland-type tumors
  • Mucoepidermoid carcinoma
  • Adenoid cystic carcinoma
  • Epithelial-myoepithelial carcinoma
  • Pleomorphic adenoma

• Papillomas
  • Squamous cell papilloma
    • Exophytic
    • Inverted
  • Glandular papilloma
  • Mixed squamous and glandular papilloma
• Adenomas
  • Sclerosing pneumocytoma
  • Alveolar adenoma
  • Papillary adenoma
  • Mucinous cystadenoma
  • Mucous gland adenoma

Mesenchymal tumors

• Pulmonary hamartoma
• Chondroma
• PEComatous tumors
  • Lymphangioleiomyomatosis
  • PEComa, benigne
    • Clear cell tumor
  • PEComa, malignant
• Congenital peribronchial myofibroblastic tumor
• Diffuse pulmonary lymphangiomatosis
• Inflammatory myofibroblastic tumor
• Epithelioid hemangioendothelioma
• Pleuropulmonary blastoma
• Synovial sarcoma
• Pulmonary artery intimal sarcoma
• Pulmonary myxoid sarcoma with EWSR1–CREB1 translocation
• Myoepithelial tumors
  • Myoepithelioma
  • Myoepithelial carcinoma

Lymphohistiocytic tumors

• Extranodal marginal zone lymphomas of mucosa-associated Lymphoid tissue (MALT lymphoma)
• Diffuse large cell lymphoma
• Lymphomatoid granulomatosis
• Intravascular large B cell lymphoma
• Pulmonary Langerhans cell histiocytosis
• Erdheim–Chester disease

Tumors of ectopic origin

• Germ cell tumors
  • Teratoma, mature
  • Teratoma, immature
• Intrapulmonary thymoma
• Melanoma
• Meningioma, NOS

References

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