Neuroblastoma laboratory tests: Difference between revisions
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| doi = 10.1016/j.suc.2005.12.008 | | doi = 10.1016/j.suc.2005.12.008 | ||
| pmid = 16580935 | | pmid = 16580935 | ||
}}</ref> | }}</ref><ref name="gov">Neuroblastoma Treatment for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#link/_534_toc Accessed on October, 7 2015</ref><ref name="pmid21736987">{{cite journal| author=Colon NC, Chung DH| title=Neuroblastoma. | journal=Adv Pediatr | year= 2011 | volume= 58 | issue= 1 | pages= 297-311 | pmid=21736987 | doi=10.1016/j.yapd.2011.03.011 | pmc=PMC3668791 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21736987 }} </ref><ref>{{Cite journal | ||
| author = [[Andrew M. Davidoff]] | | author = [[Andrew M. Davidoff]] | ||
| title = Neuroblastoma | | title = Neuroblastoma | ||
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| pmid = 958297 | | pmid = 958297 | ||
}}</ref> | }}</ref> | ||
*Blood tests | |||
**Decreased[[hemoglobin]] | |||
**Increased [[ferritin]] | |||
**Increased [[catecholamine]] | |||
**Increased [[dopamine]] | |||
**Increased [[vanillylmandelic acid]] (VMA) | |||
**Increased [[homovanillic acid]] (HVA) | |||
**Increased [[lactate dehydrogenase]] (>1500 U/ml) | |||
**Increased neuron-specific [[enolase]] (>100 ng/ml) | |||
*Urinalysis | |||
**Increased [[catecholamine]] | **Increased [[catecholamine]] | ||
**Increased[[vanillylmandelic acid]] (VMA) | **Increased[[vanillylmandelic acid]] (VMA) | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]Haytham Allaham, M.D. [3]
Overview
The laboratory findings in neuroblastoma include; ↓ hemoglobin, ↑ ferritin, ↑ catecholamine, ↑ dopamine, ↑ vanillylmandelic acid (VMA), ↑ homovanillic acid (HVA), ↑ lactate dehydrogenase and ↑ neuron-specific enolase levels. There are increased urinary catecholamine, vanillylmandelic acid (VMA) and homovanillic acid (HVA) levels.
Laboratory Findings
Laboratory findings consistent with the diagnosis of neuroblastoma include: [1][2][3][4][1][2][5][6]
- Blood tests
- Decreasedhemoglobin
- Increased ferritin
- Increased catecholamine
- Increased dopamine
- Increased vanillylmandelic acid (VMA)
- Increased homovanillic acid (HVA)
- Increased lactate dehydrogenase (>1500 U/ml)
- Increased neuron-specific enolase (>100 ng/ml)
- Urinalysis
- Increased catecholamine
- Increasedvanillylmandelic acid (VMA)
- Increasedhomovanillic acid (HVA)
References
- ↑ 1.0 1.1 Neuroblastoma Treatment for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#link/_534_toc Accessed on October, 7 2015
- ↑ 2.0 2.1 Colon NC, Chung DH (2011). "Neuroblastoma". Adv Pediatr. 58 (1): 297–311. doi:10.1016/j.yapd.2011.03.011. PMC 3668791. PMID 21736987.
- ↑ Nadja C. Colon & Dai H. Chung (2011). "Neuroblastoma". Advances in pediatrics. 58 (1): 297–311. doi:10.1016/j.yapd.2011.03.011. PMID 21736987.
- ↑ Sunghoon Kim & Dai H. Chung (2006). "Pediatric solid malignancies: neuroblastoma and Wilms' tumor". The Surgical clinics of North America. 86 (2): 469–487. doi:10.1016/j.suc.2005.12.008. PMID 16580935. Unknown parameter
|month=ignored (help) - ↑ Andrew M. Davidoff (2012). "Neuroblastoma". Seminars in pediatric surgery. 21 (1): 2–14. doi:10.1053/j.sempedsurg.2011.10.009. PMID 22248965. Unknown parameter
|month=ignored (help) - ↑ M. S. Blois & P. W. Banda (1976). "Letter: Laboratory diagnosis of neuroblastoma". The New England journal of medicine. 295 (16): 899–900. doi:10.1056/NEJM197610142951617. PMID 958297. Unknown parameter
|month=ignored (help)