Sexcord/ stromal ovarian tumors classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

There is no established system for the classification of [disease name].

OR

[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].

OR

[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3]. [Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].

OR

Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.

OR

If the staging system involves specific and characteristic findings and features: According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].

OR

The staging of [malignancy name] is based on the [staging system].

OR

There is no established system for the staging of [malignancy name].

Classification

WHO classification for ovarian sex cord-stromal tumors:

• Pure stromal tumors

* Fibroma
* Cellular fibroma
* Thecoma
* Luteinized thecoma associated with sclerosing peritonitis
* Fibrosarcoma
* Sclerosing stromal tumor
* Signet-ring stromal tumor
* Microcystic stromal tumor
* Leydig cell tumor
* Steroid cell tumor
* Steroid cell tumor, malignant

WHO classification scheme for ovarian sex cord-stromal tumors

Types	Subtypes
Pure stromal tumors	Fibroma Cellular fibroma Thecoma Luteinized thecoma associated with sclerosing peritonitis Fibrosarcoma Sclerosing stromal tumor Signet-ring stromal tumor Microcystic stromal tumor Leydig cell tumor Steroid cell tumor Steroid cell tumor, malignant
Pure sex cord tumors	Adult granulosa cell tumor Juvenile granulosa cell tumor Sertoli cell tumor Sex cord tumor with annular tubules
Mixed sex cord-stromal tumors	Sertoli-Leydig cell tumors Well-differentiated Moderately differentiated with heterologous elements Poorly differentiated with heterologous elements Retiform with heterologous elements Sex cord-stromal tumours, NOS