Paget's disease of the breast epidemiology and demographics: Difference between revisions
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
*Paget's disease of the breast occurs in 0.5–5% of all breast [[cancer]] cases and is invariably associated with underlying malignancy either overt or occult. | *Paget's disease of the breast occurs in 0.5–5% of all breast [[cancer]] cases and is invariably associated with underlying malignancy either overt or occult. | ||
* WHO revealed that there are 800,000 up to 1 million new cases of breast cancer each year.<ref name="DelalogeBachelot2016">{{cite journal|last1=Delaloge|first1=Suzette|last2=Bachelot|first2=Thomas|last3=Bidard|first3=François-Clément|last4=Espie|first4=Marc|last5=Brain|first5=Etienne|last6=Bonnefoi|first6=Hervé|last7=Gligorov|first7=Joseph|last8=Dalenc|first8=Florence|last9=Hardy-Bessard|first9=Anne-Claire|last10=Azria|first10=David|last11=Jacquin|first11=Jean-Philippe|last12=Lemonnier|first12=Jérôme|last13=Jacot|first13=William|last14=Goncalves|first14=Anthony|last15=Coutant|first15=Charles|last16=Ganem|first16=Gérard|last17=Petit|first17=Thierry|last18=Penault-Lorca|first18=Frédérique|last19=Debled|first19=Marc|last20=Campone|first20=Mario|last21=Levy|first21=Christelle|last22=Coudert|first22=Bruno|last23=Lortholary|first23=Alain|last24=Venat-Bouvet|first24=Laurence|last25=Grenier|first25=Julien|last26=Bourgeois|first26=Hugues|last27=Asselain|first27=Bernard|last28=Arvis|first28=Johanna|last29=Castro|first29=Martine|last30=Tardivon|first30=Anne|last31=Cox|first31=David G.|last32=Arveux|first32=Patrick|last33=Balleyguier|first33=Corinne|last34=André|first34=Fabrice|last35=Rouzier|first35=Roman|title=Dépistage du cancer du sein : en route vers le futur|journal=Bulletin du Cancer|volume=103|issue=9|year=2016|pages=753–763|issn=00074551|doi=10.1016/j.bulcan.2016.06.005}}</ref> | * WHO revealed that there are 800,000 up to 1 million new cases of breast cancer each year.<ref name="DelalogeBachelot2016">{{cite journal|last1=Delaloge|first1=Suzette|last2=Bachelot|first2=Thomas|last3=Bidard|first3=François-Clément|last4=Espie|first4=Marc|last5=Brain|first5=Etienne|last6=Bonnefoi|first6=Hervé|last7=Gligorov|first7=Joseph|last8=Dalenc|first8=Florence|last9=Hardy-Bessard|first9=Anne-Claire|last10=Azria|first10=David|last11=Jacquin|first11=Jean-Philippe|last12=Lemonnier|first12=Jérôme|last13=Jacot|first13=William|last14=Goncalves|first14=Anthony|last15=Coutant|first15=Charles|last16=Ganem|first16=Gérard|last17=Petit|first17=Thierry|last18=Penault-Lorca|first18=Frédérique|last19=Debled|first19=Marc|last20=Campone|first20=Mario|last21=Levy|first21=Christelle|last22=Coudert|first22=Bruno|last23=Lortholary|first23=Alain|last24=Venat-Bouvet|first24=Laurence|last25=Grenier|first25=Julien|last26=Bourgeois|first26=Hugues|last27=Asselain|first27=Bernard|last28=Arvis|first28=Johanna|last29=Castro|first29=Martine|last30=Tardivon|first30=Anne|last31=Cox|first31=David G.|last32=Arveux|first32=Patrick|last33=Balleyguier|first33=Corinne|last34=André|first34=Fabrice|last35=Rouzier|first35=Roman|title=Dépistage du cancer du sein : en route vers le futur|journal=Bulletin du Cancer|volume=103|issue=9|year=2016|pages=753–763|issn=00074551|doi=10.1016/j.bulcan.2016.06.005}}</ref> | ||
*An underlying breast carcinoma is found in >90% of patients with Paget's disease. | |||
**The majority of these cases are invasive disease although 40 – 45% are associated with [[ductal carcinoma in situ]].<ref name="SubramanianBirch2007">{{cite journal|last1=Subramanian|first1=Ashok|last2=Birch|first2=Hilary|last3=McAvinchey|first3=Rita|last4=Stacey-Clear|first4=Adam|title=Pagets disease of uncertain origin: case report|journal=International Seminars in Surgical Oncology|volume=4|issue=1|year=2007|pages=12|issn=14777800|doi=10.1186/1477-7800-4-12}}</ref> | |||
===Age=== | ===Age=== | ||
*Paget's disease of the breast is more prevalent in postmenopausal women, usually after the sixth decade of life, but it has also been reported in adolescent and elderly patients. | *Paget's disease of the breast is more prevalent in postmenopausal women, usually after the sixth decade of life, but it has also been reported in adolescent and elderly patients. |
Revision as of 12:01, 8 March 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Epidemiology and Demographics
- Paget's disease of the breast occurs in 0.5–5% of all breast cancer cases and is invariably associated with underlying malignancy either overt or occult.
- WHO revealed that there are 800,000 up to 1 million new cases of breast cancer each year.[1]
- An underlying breast carcinoma is found in >90% of patients with Paget's disease.
- The majority of these cases are invasive disease although 40 – 45% are associated with ductal carcinoma in situ.[2]
Age
- Paget's disease of the breast is more prevalent in postmenopausal women, usually after the sixth decade of life, but it has also been reported in adolescent and elderly patients.
Gender
- Females are more commonly affected with Paget's disease of the breast than males.
- Male breast cancer accounts for less than 1% of all breast cancer and Paget's disease represents 1-3% of all breast malignancies.[3]
References
- ↑ Delaloge, Suzette; Bachelot, Thomas; Bidard, François-Clément; Espie, Marc; Brain, Etienne; Bonnefoi, Hervé; Gligorov, Joseph; Dalenc, Florence; Hardy-Bessard, Anne-Claire; Azria, David; Jacquin, Jean-Philippe; Lemonnier, Jérôme; Jacot, William; Goncalves, Anthony; Coutant, Charles; Ganem, Gérard; Petit, Thierry; Penault-Lorca, Frédérique; Debled, Marc; Campone, Mario; Levy, Christelle; Coudert, Bruno; Lortholary, Alain; Venat-Bouvet, Laurence; Grenier, Julien; Bourgeois, Hugues; Asselain, Bernard; Arvis, Johanna; Castro, Martine; Tardivon, Anne; Cox, David G.; Arveux, Patrick; Balleyguier, Corinne; André, Fabrice; Rouzier, Roman (2016). "Dépistage du cancer du sein : en route vers le futur". Bulletin du Cancer. 103 (9): 753–763. doi:10.1016/j.bulcan.2016.06.005. ISSN 0007-4551.
- ↑ Subramanian, Ashok; Birch, Hilary; McAvinchey, Rita; Stacey-Clear, Adam (2007). "Pagets disease of uncertain origin: case report". International Seminars in Surgical Oncology. 4 (1): 12. doi:10.1186/1477-7800-4-12. ISSN 1477-7800.
- ↑ Fouad, Dina (2011). "Paget's disease of the breast in a male with lymphomatoid papulosis: a case report". Journal of Medical Case Reports. 5 (1): 43. doi:10.1186/1752-1947-5-43. ISSN 1752-1947.