Nasopharyngeal carcinoma historical perspective: Difference between revisions
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==Overview== | ==Overview== | ||
The association between [[EBV]] and nasopharyngeal carcinoma was made in1970. In 1970, Zur Hausen and et al, were the first to [[extract]] [[EBV]] [[DNA]] from NPC [[tumors]] by using [[DNA hybridization]] method. In 1970, Henle and et al, revealed the link between stage of NPC [[tumors]] and [[Epstein Barr virus|EBV]] [[antibody]] [[titer]]. In 1973, Wolf and et al, found [[EBV]] [[DNA]] in NPC [[tumor cell]]<nowiki/>s by [[in situ]] [[hybridization]] methods but not in infiltrating [[lymphoid cell]]<nowiki/>s. Babe Ruth, a famous baseball player suffered from nasopharyngeal cancer. | |||
==Historical Perspective== | ==Historical Perspective== | ||
===Discovery=== | ===Discovery=== | ||
*The association between EBV and nasopharyngeal carcinoma was made in1970.<ref>{{Cite journal | *The association between [[EBV]] and nasopharyngeal carcinoma was made in1970.<ref>{{Cite journal | ||
| author = [[H. zur Hausen]], [[H. Schulte-Holthausen]], [[G. Klein]], [[W. Henle]], [[G. Henle]], [[P. Clifford]] & [[L. Santesson]] | | author = [[H. zur Hausen]], [[H. Schulte-Holthausen]], [[G. Klein]], [[W. Henle]], [[G. Henle]], [[P. Clifford]] & [[L. Santesson]] | ||
| title = EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx | | title = EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx | ||
| Line 18: | Line 20: | ||
| pmid = 4320657 | | pmid = 4320657 | ||
}}</ref> | }}</ref> | ||
*In 1970, Zur Hausen and et al were the first to extract EBV DNA from NPC tumors by using DNA hybridization method.<ref>{{Cite journal | *In 1970, Zur Hausen and et al, were the first to [[extract]] [[EBV]] [[DNA]] from NPC [[tumors]] by using [[DNA hybridization]] method.<ref>{{Cite journal | ||
| author = [[H. zur Hausen]], [[H. Schulte-Holthausen]], [[G. Klein]], [[W. Henle]], [[G. Henle]], [[P. Clifford]] & [[L. Santesson]] | | author = [[H. zur Hausen]], [[H. Schulte-Holthausen]], [[G. Klein]], [[W. Henle]], [[G. Henle]], [[P. Clifford]] & [[L. Santesson]] | ||
| title = EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx | | title = EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx | ||
| Line 29: | Line 31: | ||
| pmid = 4320657 | | pmid = 4320657 | ||
}}</ref> | }}</ref> | ||
*In 1970, Henle and et al revealed the link between stage of NPC tumors and EBV antibody titer.<ref>{{Cite journal | *In 1970, Henle and et al, revealed the link between stage of NPC [[tumors]] and [[Epstein Barr virus|EBV]] [[antibody]] [[titer]].<ref>{{Cite journal | ||
| author = [[W. Henle]], [[G. Henle]], [[H. C. Ho]], [[P. Burtin]], [[Y. Cachin]], [[P. Clifford]], [[A. de Schryver]], [[G. de-The]], [[V. Diehl]] & [[G. Klein]] | | author = [[W. Henle]], [[G. Henle]], [[H. C. Ho]], [[P. Burtin]], [[Y. Cachin]], [[P. Clifford]], [[A. de Schryver]], [[G. de-The]], [[V. Diehl]] & [[G. Klein]] | ||
| title = Antibodies to Epstein-Barr virus in nasopharyngeal carcinoma, other head and neck neoplasms, and control groups | | title = Antibodies to Epstein-Barr virus in nasopharyngeal carcinoma, other head and neck neoplasms, and control groups | ||
| Line 40: | Line 42: | ||
| pmid = 11515035 | | pmid = 11515035 | ||
}}</ref> | }}</ref> | ||
*In 1973, Wolf and et al found EBV DNA in NPC tumor | *In 1973, Wolf and et al, found [[EBV]] [[DNA]] in NPC [[tumor cell]]<nowiki/>s by [[in situ]] [[hybridization]] methods but not in infiltrating [[lymphoid cell]]<nowiki/>s.<ref>{{Cite journal | ||
| author = [[H. Wolf]], [[H. zur Hausen]] & [[V. Becker]] | | author = [[H. Wolf]], [[H. zur Hausen]] & [[V. Becker]] | ||
| title = EB viral genomes in epithelial nasopharyngeal carcinoma cells | | title = EB viral genomes in epithelial nasopharyngeal carcinoma cells | ||
| Line 53: | Line 55: | ||
===Famous Cases=== | ===Famous Cases=== | ||
Babe Ruth, a famous baseball player suffered from nasopharyngeal cancer.<ref name="10-famous-people-who-have-suffered-from-head-and-neck-cancer/">{{cite web |url=http://faulknerent.com/10-famous-people-who-have-suffered-from-head-and-neck-cancer/ |title=10 Famous People Who Have Suffered from Head and Neck Cancer – Dr. Jeffrey Faulkner, ENT |format= |work= |accessdate=}}</ref> | * Babe Ruth, a famous baseball player suffered from nasopharyngeal cancer.<ref name="10-famous-people-who-have-suffered-from-head-and-neck-cancer/">{{cite web |url=http://faulknerent.com/10-famous-people-who-have-suffered-from-head-and-neck-cancer/ |title=10 Famous People Who Have Suffered from Head and Neck Cancer – Dr. Jeffrey Faulkner, ENT |format= |work= |accessdate=}}</ref> | ||
==References== | ==References== | ||
Revision as of 19:13, 13 March 2019
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Nasopharyngeal carcinoma Microchapters |
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Differentiating Nasopharyngeal carcinoma from other Diseases |
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Nasopharyngeal carcinoma historical perspective On the Web |
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Risk calculators and risk factors for Nasopharyngeal carcinoma historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]
Overview
The association between EBV and nasopharyngeal carcinoma was made in1970. In 1970, Zur Hausen and et al, were the first to extract EBV DNA from NPC tumors by using DNA hybridization method. In 1970, Henle and et al, revealed the link between stage of NPC tumors and EBV antibody titer. In 1973, Wolf and et al, found EBV DNA in NPC tumor cells by in situ hybridization methods but not in infiltrating lymphoid cells. Babe Ruth, a famous baseball player suffered from nasopharyngeal cancer.
Historical Perspective
Discovery
- The association between EBV and nasopharyngeal carcinoma was made in1970.[1]
- In 1970, Zur Hausen and et al, were the first to extract EBV DNA from NPC tumors by using DNA hybridization method.[2]
- In 1970, Henle and et al, revealed the link between stage of NPC tumors and EBV antibody titer.[3]
- In 1973, Wolf and et al, found EBV DNA in NPC tumor cells by in situ hybridization methods but not in infiltrating lymphoid cells.[4]
Famous Cases
- Babe Ruth, a famous baseball player suffered from nasopharyngeal cancer.[5]
References
- ↑ H. zur Hausen, H. Schulte-Holthausen, G. Klein, W. Henle, G. Henle, P. Clifford & L. Santesson (1970). "EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx". Nature. 228 (5276): 1056–1058. PMID 4320657. Unknown parameter
|month=ignored (help) - ↑ H. zur Hausen, H. Schulte-Holthausen, G. Klein, W. Henle, G. Henle, P. Clifford & L. Santesson (1970). "EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx". Nature. 228 (5276): 1056–1058. PMID 4320657. Unknown parameter
|month=ignored (help) - ↑ W. Henle, G. Henle, H. C. Ho, P. Burtin, Y. Cachin, P. Clifford, A. de Schryver, G. de-The, V. Diehl & G. Klein (1970). "Antibodies to Epstein-Barr virus in nasopharyngeal carcinoma, other head and neck neoplasms, and control groups". Journal of the National Cancer Institute. 44 (1): 225–231. PMID 11515035. Unknown parameter
|month=ignored (help) - ↑ H. Wolf, H. zur Hausen & V. Becker (1973). "EB viral genomes in epithelial nasopharyngeal carcinoma cells". Nature: New biology. 244 (138): 245–247. PMID 4353684. Unknown parameter
|month=ignored (help) - ↑ "10 Famous People Who Have Suffered from Head and Neck Cancer – Dr. Jeffrey Faulkner, ENT".