Sexcord/ stromal ovarian tumors risk factors: Difference between revisions
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==Risk Factors== | ==Risk Factors== | ||
The risk factors for the development of sexcord-stromal ovarian tumors are as follows: | The risk factors for the development of sexcord-stromal ovarian tumors are as follows:<ref name="pmid24530563">{{cite journal |vauthors=Sieh W, Sundquist K, Sundquist J, Winkleby MA, Crump C |title=Intrauterine factors and risk of nonepithelial ovarian cancers |journal=Gynecol. Oncol. |volume=133 |issue=2 |pages=293–7 |date=May 2014 |pmid=24530563 |pmc=4006291 |doi=10.1016/j.ygyno.2014.02.007 |url=}}</ref> | ||
*Preterm birth is a risk factor for developing sex cord-stromal tumors | *Preterm birth is a risk factor for developing sex cord-stromal tumors | ||
*High gonadotropin levels in preterm girls could mediate disease risk by the proliferative and steroidogenic effects of FSH and LH on granulosa and theca cells | *High gonadotropin levels in preterm girls could mediate disease risk by the proliferative and steroidogenic effects of FSH and LH on granulosa and theca cells | ||
Revision as of 19:07, 28 March 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
There are no established risk factors for [disease name].
OR
The most potent risk factor in the development of [disease name] is [risk factor 1]. Other risk factors include [risk factor 2], [risk factor 3], and [risk factor 4].
OR
Common risk factors in the development of [disease name] include [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].
OR
Common risk factors in the development of [disease name] may be occupational, environmental, genetic, and viral.
Risk Factors
The risk factors for the development of sexcord-stromal ovarian tumors are as follows:[1]
- Preterm birth is a risk factor for developing sex cord-stromal tumors
- High gonadotropin levels in preterm girls could mediate disease risk by the proliferative and steroidogenic effects of FSH and LH on granulosa and theca cells
- High circulating levels of androgens during pregnancy were associated with increased risk of maternal sex-cord stromal tumors( indicating that elevated androgens may also play a role in the pathogenesis of sex-cord stromal tumors)
References
- ↑ Sieh W, Sundquist K, Sundquist J, Winkleby MA, Crump C (May 2014). "Intrauterine factors and risk of nonepithelial ovarian cancers". Gynecol. Oncol. 133 (2): 293–7. doi:10.1016/j.ygyno.2014.02.007. PMC 4006291. PMID 24530563.