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'''WHO classification for ovarian sex cord-stromal tumors''':<ref name="pmid26054417">{{cite journal |vauthors=Horta M, Cunha TM |title=Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists |journal=Diagn Interv Radiol |volume=21 |issue=4 |pages=277–86 |date=2015 |pmid=26054417 |pmc=4498422 |doi=10.5152/dir.2015.34414 |url=}}</ref><ref name="pmid26894303">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications |journal=Arch. Gynecol. Obstet. |volume=293 |issue=4 |pages=695–700 |date=April 2016 |pmid=26894303 |doi=10.1007/s00404-016-4035-8 |url=}}</ref><ref name="pmid26556905">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer |journal=Geburtshilfe Frauenheilkd |volume=75 |issue=10 |pages=1021–1027 |date=October 2015 |pmid=26556905 |pmc=4629993 |doi=10.1055/s-0035-1558079 |url=}}</ref><ref name="pmid21716157">{{cite journal |vauthors=McCluggage WG |title=Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis |journal=Pathology |volume=43 |issue=5 |pages=420–32 |date=August 2011 |pmid=21716157 |doi=10.1097/PAT.0b013e328348a6e7 |url=}}</ref><ref name="ChenRuiz2003">{{cite journal|last1=Chen|first1=Vivien W.|last2=Ruiz|first2=Bernardo|last3=Killeen|first3=Jeffrey L.|last4=Cot�|first4=Timothy R.|last5=Wu|first5=Xiao Cheng|last6=Correa|first6=Catherine N.|last7=Howe|first7=Holly L.|title=Pathology and classification of ovarian tumors|journal=Cancer|volume=97|issue=S10|year=2003|pages=2631–2642|issn=0008-543X|doi=10.1002/cncr.11345}}</ref> | '''WHO classification for ovarian sex cord-stromal tumors''':<ref name="pmid26054417">{{cite journal |vauthors=Horta M, Cunha TM |title=Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists |journal=Diagn Interv Radiol |volume=21 |issue=4 |pages=277–86 |date=2015 |pmid=26054417 |pmc=4498422 |doi=10.5152/dir.2015.34414 |url=}}</ref><ref name="pmid26894303">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications |journal=Arch. Gynecol. Obstet. |volume=293 |issue=4 |pages=695–700 |date=April 2016 |pmid=26894303 |doi=10.1007/s00404-016-4035-8 |url=}}</ref><ref name="pmid26556905">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer |journal=Geburtshilfe Frauenheilkd |volume=75 |issue=10 |pages=1021–1027 |date=October 2015 |pmid=26556905 |pmc=4629993 |doi=10.1055/s-0035-1558079 |url=}}</ref><ref name="pmid21716157">{{cite journal |vauthors=McCluggage WG |title=Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis |journal=Pathology |volume=43 |issue=5 |pages=420–32 |date=August 2011 |pmid=21716157 |doi=10.1097/PAT.0b013e328348a6e7 |url=}}</ref><ref name="ChenRuiz2003">{{cite journal|last1=Chen|first1=Vivien W.|last2=Ruiz|first2=Bernardo|last3=Killeen|first3=Jeffrey L.|last4=Cot�|first4=Timothy R.|last5=Wu|first5=Xiao Cheng|last6=Correa|first6=Catherine N.|last7=Howe|first7=Holly L.|title=Pathology and classification of ovarian tumors|journal=Cancer|volume=97|issue=S10|year=2003|pages=2631–2642|issn=0008-543X|doi=10.1002/cncr.11345}}</ref> | ||
*'''Pure stromal tumors''' | *'''Pure stromal tumors''' | ||
** Fibroma | ** [[Fibroma]] | ||
** Cellular fibroma | ** [[Cellular]] [[fibroma]] | ||
**Thecoma | **[[Thecoma]] | ||
** Luteinized thecoma associated with sclerosing peritonitis | ** Luteinized [[thecoma]] associated with sclerosing [[peritonitis]] | ||
** Fibrosarcoma | ** [[Fibrosarcoma]] | ||
** Sclerosing stromal tumor | ** Sclerosing [[stromal]] [[tumor]] | ||
** Signet-ring stromal tumor | ** [[Signet ring|Signet-ring]] [[stromal]] [[tumor]] | ||
** | ** [[Microcytic|Microcy]]<nowiki/>stic [[stromal]] [[tumor]] | ||
** Leydig cell tumor | ** [[Leydig cell tumor]] | ||
** Steroid cell tumor | ** Steroid cell tumor | ||
** Steroid cell tumor, malignant | ** Steroid cell tumor, [[malignant]] | ||
*'''Pure sex cord tumors''' | *'''Pure sex cord tumors''' | ||
** Adult granulosa cell tumor | ** [[Granulosa cell tumor|Adult granulosa cell tumor]] | ||
**Juvenile granulosa cell tumor | **Juvenile [[granulosa cell tumor]] | ||
** Sertoli cell tumor | ** Sertoli cell tumor | ||
** Sex cord tumor with annular tubules | ** Sex cord tumor with annular tubules | ||
Revision as of 19:06, 1 May 2019
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Sexcord/ stromal ovarian tumors Microchapters |
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Differentiating Sexcord/ Stromal Ovarian Tumors from other Diseases |
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Sexcord/ stromal ovarian tumors classification On the Web |
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Risk calculators and risk factors for Sexcord/ stromal ovarian tumors classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: ; Maneesha Nandimandalam, M.B.B.S.[2]
Overview
Sexcord/ stromal ovarian tumors may be classified according to WHO into 3 subtypes: Pure stromal tumors, pure sexcord tumors, mixed stromal and sexcord tumors. Histological classification of sexcord-stromal ovarian tumors includes granulosa stromal cell tumors, sertoli leydig cell tumors, gynandroblastoma, and unclassified.
Classification
WHO classification for ovarian sex cord-stromal tumors:[1][2][3][4][5]
- Pure stromal tumors
- Fibroma
- Cellular fibroma
- Thecoma
- Luteinized thecoma associated with sclerosing peritonitis
- Fibrosarcoma
- Sclerosing stromal tumor
- Signet-ring stromal tumor
- Microcystic stromal tumor
- Leydig cell tumor
- Steroid cell tumor
- Steroid cell tumor, malignant
- Pure sex cord tumors
- Adult granulosa cell tumor
- Juvenile granulosa cell tumor
- Sertoli cell tumor
- Sex cord tumor with annular tubules
- Mixed sex cord-stromal tumors
- Sertoli-Leydig cell tumors
- Well-differentiated
- Moderately differentiated with heterologous elements
- Poorly differentiated with heterologous elements
- Retiform with heterologous elements
- Sex cord-stromal tumours, NOS
- Sertoli-Leydig cell tumors
| Types | Subtypes |
| Pure stromal tumors |
|
| Pure sex cord tumors |
|
| Mixed sex cord-stromal tumors |
|
NOS, not otherwise specified.
| Types | Subtypes |
| Granulosa‐stromal cell tumors |
|
| Sertoli–Leydig cell tumors |
|
| Gynandroblastoma | No specific subtypes |
| Unclassified | No specific subtypes |
International Agency for Research on Cancer Histologic Groups of Ovarian Tumors Classification from International agency for research on cancer is summarized in the table: [2][7][3]
| Ovarian tumors |
|---|
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References
- ↑ 1.0 1.1 Horta M, Cunha TM (2015). "Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists". Diagn Interv Radiol. 21 (4): 277–86. doi:10.5152/dir.2015.34414. PMC 4498422. PMID 26054417.
- ↑ 2.0 2.1 2.2 Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J (April 2016). "The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications". Arch. Gynecol. Obstet. 293 (4): 695–700. doi:10.1007/s00404-016-4035-8. PMID 26894303.
- ↑ 3.0 3.1 3.2 Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J (October 2015). "Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer". Geburtshilfe Frauenheilkd. 75 (10): 1021–1027. doi:10.1055/s-0035-1558079. PMC 4629993. PMID 26556905.
- ↑ 4.0 4.1 McCluggage WG (August 2011). "Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis". Pathology. 43 (5): 420–32. doi:10.1097/PAT.0b013e328348a6e7. PMID 21716157.
- ↑ 5.0 5.1 Chen, Vivien W.; Ruiz, Bernardo; Killeen, Jeffrey L.; Cot�, Timothy R.; Wu, Xiao Cheng; Correa, Catherine N.; Howe, Holly L. (2003). "Pathology and classification of ovarian tumors". Cancer. 97 (S10): 2631–2642. doi:10.1002/cncr.11345. ISSN 0008-543X. replacement character in
|last4=at position 4 (help) - ↑ Fuller, P.J.; Leung, D.; Chu, S. (2017). "Genetics and genomics of ovarian sex cord-stromal tumors". Clinical Genetics. 91 (2): 285–291. doi:10.1111/cge.12917. ISSN 0009-9163.
- ↑ "onlinelibrary.wiley.com".