Sexcord/ stromal ovarian tumors classification: Difference between revisions

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{{Sexcord/ stromal ovarian tumors}}
{{Sexcord/ stromal ovarian tumors}}


{{CMG}}; {{AE}} ;{{M.N}}
{{CMG}}; {{AE}} {{M.N}}
==Overview==
==Overview==


Sexcord/ stromal ovarian tumors may be classified according to [[WHO]] into 3 subtypes: Pure stromal tumors, pure sexcord tumors, mixed stromal and sexcord tumors. [[Histological]] [[classification]] of sexcord-stromal ovarian tumors includes [[granulosa]] stromal cell tumors, [[Sertoli-Leydig cell tumour|sertoli leydig cell tumors]], gynandroblastoma, and unclassified.
Sexcord/ stromal ovarian tumors may be classified according to [[WHO]] into 3 subtypes: pure stromal tumors, pure sexcord tumors, mixed stromal and sexcord tumors. [[Histological]] [[classification]] of sexcord-stromal ovarian tumors includes [[granulosa]] stromal cell tumors, [[Sertoli-Leydig cell tumour|sertoli leydig cell tumors]], gynandroblastoma, and unclassified.


==Classification==
==Classification==
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** Sclerosing [[stromal]] [[tumor]]
** Sclerosing [[stromal]] [[tumor]]
** [[Signet ring|Signet-ring]] [[stromal]] [[tumor]]
** [[Signet ring|Signet-ring]] [[stromal]] [[tumor]]
** [[Microcytic|Microcy]]<nowiki/>stic [[stromal]] [[tumor]]
**<nowiki/>[[Microcytic|Microcy]]<nowiki/>stic [[stromal]] [[tumor]]
** [[Leydig cell tumor]]
** [[Leydig cell tumor|Leydig]] <nowiki/>[[Leydig cell tumor|cell tumor]]
** Steroid cell tumor
** Steroid cell tumor
** Steroid cell tumor, [[malignant]]
** Steroid cell tumor, [[malignant]]
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** Retiform with heterologous elements
** Retiform with heterologous elements
* Sex cord-stromal tumours, NOS
* Sex cord-stromal tumours, NOS
|-
| colspan="2" |NOS, not otherwise specified
|}
|}
NOS, not otherwise specified.


{| class="wikitable"
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'''International Agency for Research on Cancer Histologic Groups of Ovarian Tumors'''  
'''International Agency for Research on Cancer Histologic Groups of Ovarian Tumors'''  
Classification from '''International agency for research on cancer''' is summarized in the table: <ref name="pmid26894303">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications |journal=Arch. Gynecol. Obstet. |volume=293 |issue=4 |pages=695–700 |date=April 2016 |pmid=26894303 |doi=10.1007/s00404-016-4035-8 |url=}}</ref><ref name="urlonlinelibrary.wiley.com">{{cite web |url=https://onlinelibrary.wiley.com/doi/pdf/10.1002/cncr.11345 |title=onlinelibrary.wiley.com |format= |work= |accessdate=}}</ref><ref name="pmid26556905">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer |journal=Geburtshilfe Frauenheilkd |volume=75 |issue=10 |pages=1021–1027 |date=October 2015 |pmid=26556905 |pmc=4629993 |doi=10.1055/s-0035-1558079 |url=}}</ref>
Classification from '''International agency for research on cancer''' is summarized in the table: <ref name="pmid26894303">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications |journal=Arch. Gynecol. Obstet. |volume=293 |issue=4 |pages=695–700 |date=April 2016 |pmid=26894303 |doi=10.1007/s00404-016-4035-8 |url=}}</ref><ref name="urlonlinelibrary.wiley.com">{{cite web |url=https://onlinelibrary.wiley.com/doi/pdf/10.1002/cncr.11345 |title=onlinelibrary.wiley.com |format= |work= |accessdate=}}</ref><ref name="pmid26556905">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer |journal=Geburtshilfe Frauenheilkd |volume=75 |issue=10 |pages=1021–1027 |date=October 2015 |pmid=26556905 |pmc=4629993 |doi=10.1055/s-0035-1558079 |url=}}</ref>
{| class="wikitable"
{| class="wikitable"

Latest revision as of 17:24, 29 May 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2]

Overview

Sexcord/ stromal ovarian tumors may be classified according to WHO into 3 subtypes: pure stromal tumors, pure sexcord tumors, mixed stromal and sexcord tumors. Histological classification of sexcord-stromal ovarian tumors includes granulosa stromal cell tumors, sertoli leydig cell tumors, gynandroblastoma, and unclassified.

Classification

WHO classification for ovarian sex cord-stromal tumors:[1][2][3][4][5]

WHO classification scheme for ovarian sex cord-stromal tumors[1][2][3][4][5]
Types Subtypes
Pure stromal tumors
Pure sex cord tumors
Mixed sex cord-stromal tumors
  • Sertoli-Leydig cell tumors
    • Well-differentiated
    • Moderately differentiated with heterologous elements
    • Poorly differentiated with heterologous elements
    • Retiform with heterologous elements
  • Sex cord-stromal tumours, NOS
NOS, not otherwise specified
Histological classification of ovarian sex cord‐stromal tumors[6]
Types Subtypes
Granulosa‐stromal cell tumors
Sertoli–Leydig cell tumors
Gynandroblastoma No specific subtypes
Unclassified No specific subtypes

International Agency for Research on Cancer Histologic Groups of Ovarian Tumors

Classification from International agency for research on cancer is summarized in the table: [2][7][3]

Ovarian tumors

References

  1. ↑ 1.0 1.1 Horta M, Cunha TM (2015). "Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists". Diagn Interv Radiol. 21 (4): 277–86. doi:10.5152/dir.2015.34414. PMC 4498422. PMID 26054417.
  2. ↑ 2.0 2.1 2.2 Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J (April 2016). "The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications". Arch. Gynecol. Obstet. 293 (4): 695–700. doi:10.1007/s00404-016-4035-8. PMID 26894303.
  3. ↑ 3.0 3.1 3.2 Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J (October 2015). "Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer". Geburtshilfe Frauenheilkd. 75 (10): 1021–1027. doi:10.1055/s-0035-1558079. PMC 4629993. PMID 26556905.
  4. ↑ 4.0 4.1 McCluggage WG (August 2011). "Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis". Pathology. 43 (5): 420–32. doi:10.1097/PAT.0b013e328348a6e7. PMID 21716157.
  5. ↑ 5.0 5.1 Chen, Vivien W.; Ruiz, Bernardo; Killeen, Jeffrey L.; Cot�, Timothy R.; Wu, Xiao Cheng; Correa, Catherine N.; Howe, Holly L. (2003). "Pathology and classification of ovarian tumors". Cancer. 97 (S10): 2631–2642. doi:10.1002/cncr.11345. ISSN 0008-543X. replacement character in |last4= at position 4 (help)
  6. ↑ Fuller, P.J.; Leung, D.; Chu, S. (2017). "Genetics and genomics of ovarian sex cord-stromal tumors". Clinical Genetics. 91 (2): 285–291. doi:10.1111/cge.12917. ISSN 0009-9163.
  7. ↑ "onlinelibrary.wiley.com".

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