Sexcord/ stromal ovarian tumors overview: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
The exact [[pathogenesis]] of sexcord/ stromal ovarian tumors is not fully understood. [[Mutations]] mainly involving [[FOXL2]], [[DICER1]], [[STK11]] are involved. They are associated with [[ollier disease]] and [[Maffucci's syndrome|maffucci syndrome]].The [[microscopic]] [[pathology]] varies with the individual subtype of sexcord stromal ovarian tumors. | |||
==Causes== | ==Causes== | ||
Revision as of 18:39, 5 May 2019
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Sexcord/ stromal ovarian tumors Microchapters |
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Differentiating Sexcord/ Stromal Ovarian Tumors from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Sexcord/ stromal ovarian tumors overview On the Web |
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American Roentgen Ray Society Images of Sexcord/ stromal ovarian tumors overview |
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Risk calculators and risk factors for Sexcord/ stromal ovarian tumors overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: ; Maneesha Nandimandalam, M.B.B.S.[2]
Overview
Historical Perspective
Classification
Sexcord/ stromal ovarian tumors may be classified according to WHO into 3 subtypes: Pure stromal tumors, pure sexcord tumors, mixed stromal and sexcord tumors. Histological classification of sexcord-stromal ovarian tumors includes granulosa stromal cell tumors, sertoli leydig cell tumors, gynandroblastoma, and unclassified.
Pathophysiology
The exact pathogenesis of sexcord/ stromal ovarian tumors is not fully understood. Mutations mainly involving FOXL2, DICER1, STK11 are involved. They are associated with ollier disease and maffucci syndrome.The microscopic pathology varies with the individual subtype of sexcord stromal ovarian tumors.