Papillary thyroid cancer laboratory findings: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Papillary thyroid cancer}} | {{Papillary thyroid cancer}} | ||
{{CMG}}; {{AE}} {{Ammu}} | {{CMG}}; {{AE}} {{Ammu}} {{Sahar}} | ||
==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of papillary thyroid cancer include presence of tumor markers such as thyroglobulin. [[Thyroglobulin]] can be used as a [[tumor marker]] for well-[[Cellular differentiation|differentiated]] papillary thyroid cancer. | Laboratory findings consistent with the [[diagnosis]] of papillary thyroid cancer include presence of tumor markers such as [[thyroglobulin]]. [[Thyroglobulin]] can be used as a [[tumor marker]] for well-[[Cellular differentiation|differentiated]] papillary thyroid cancer. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
* Laboratory findings consistent with the diagnosis of papillary thyroid cancer include presence of tumor markers such as thyroglobulin. [[Thyroglobulin]] can be used as a [[tumor marker]] for well-[[Cellular differentiation|differentiated]] papillary thyroid cancer.<ref name="pmid18060877">{{cite journal |author=Lin JD |title=Thyroglobulin and human thyroid cancer |journal=Clin Chim Acta |volume= 388|issue= 1–2|pages= 15–21|year=2007 |pmid=18060877 |doi=10.1016/j.cca.2007.11.002}}</ref><ref name="pmid17673127">{{cite journal |author=Tuttle RM, Leboeuf R, Martorella AJ |title=Papillary thyroid cancer: monitoring and therapy |journal=Endocrinol. Metab. Clin. North Am. |volume=36 |issue=3 |pages=753–78, vii |year=2007 |pmid=17673127 |doi=10.1016/j.ecl.2007.04.004}}</ref> | * Laboratory findings consistent with the [[diagnosis]] of papillary thyroid cancer include presence of tumor markers such as [[thyroglobulin]]. [[Thyroglobulin]] can be used as a [[tumor marker]] for well-[[Cellular differentiation|differentiated]] papillary thyroid cancer.<ref name="pmid18060877">{{cite journal |author=Lin JD |title=Thyroglobulin and human thyroid cancer |journal=Clin Chim Acta |volume= 388|issue= 1–2|pages= 15–21|year=2007 |pmid=18060877 |doi=10.1016/j.cca.2007.11.002}}</ref><ref name="pmid17673127">{{cite journal |author=Tuttle RM, Leboeuf R, Martorella AJ |title=Papillary thyroid cancer: monitoring and therapy |journal=Endocrinol. Metab. Clin. North Am. |volume=36 |issue=3 |pages=753–78, vii |year=2007 |pmid=17673127 |doi=10.1016/j.ecl.2007.04.004}}</ref> | ||
* Reduced expression of [[ATP5E]] is significantly associated with the diagnosis of papillary thyroid cancer and may serve as an early tumor marker of the disease.<ref>{{cite journal|last1=Hurtado-López|first1=LM|last2=Fernández-Ramírez|first2=F|last3=Martínez-Peñafiel|first3=E|last4=Carrillo Ruiz|first4=JD|last5=Herrera González|first5=NE|title=Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early Tumor Marker?|journal=Medical science monitor : international medical journal of experimental and clinical research|date=16 June 2015|volume=21|pages=1745-51|pmid=26079849}}</ref> | * Reduced expression of [[ATP5E]] is significantly associated with the diagnosis of papillary thyroid cancer and may serve as an early tumor marker of the disease.<ref>{{cite journal|last1=Hurtado-López|first1=LM|last2=Fernández-Ramírez|first2=F|last3=Martínez-Peñafiel|first3=E|last4=Carrillo Ruiz|first4=JD|last5=Herrera González|first5=NE|title=Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early Tumor Marker?|journal=Medical science monitor : international medical journal of experimental and clinical research|date=16 June 2015|volume=21|pages=1745-51|pmid=26079849}}</ref> | ||
* [[Thyroid cancer]] rarely affects thyroid endocrine function. Therefore, [[thyroid function test]] is not [[diagnostic]] for the papillary thyroid cancer.<ref>{{cite book | last = DeLellis | first = Ronald | title = Pathology and genetics of tumours of endocrine organs | publisher = IARC Press | location = Lyon | year = 2004 | isbn = 92-832-2416-7 }}</ref> | * [[Thyroid cancer]] rarely affects thyroid endocrine function. Therefore, [[thyroid function test]] is not [[diagnostic]] for the papillary thyroid cancer.<ref>{{cite book | last = DeLellis | first = Ronald | title = Pathology and genetics of tumours of endocrine organs | publisher = IARC Press | location = Lyon | year = 2004 | isbn = 92-832-2416-7 }}</ref> | ||
Revision as of 19:16, 13 August 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2] Sahar Memar Montazerin, M.D.[3]
Overview
Laboratory findings consistent with the diagnosis of papillary thyroid cancer include presence of tumor markers such as thyroglobulin. Thyroglobulin can be used as a tumor marker for well-differentiated papillary thyroid cancer.
Laboratory Findings
- Laboratory findings consistent with the diagnosis of papillary thyroid cancer include presence of tumor markers such as thyroglobulin. Thyroglobulin can be used as a tumor marker for well-differentiated papillary thyroid cancer.[1][2]
- Reduced expression of ATP5E is significantly associated with the diagnosis of papillary thyroid cancer and may serve as an early tumor marker of the disease.[3]
- Thyroid cancer rarely affects thyroid endocrine function. Therefore, thyroid function test is not diagnostic for the papillary thyroid cancer.[4]
References
- ↑ Lin JD (2007). "Thyroglobulin and human thyroid cancer". Clin Chim Acta. 388 (1–2): 15–21. doi:10.1016/j.cca.2007.11.002. PMID 18060877.
- ↑ Tuttle RM, Leboeuf R, Martorella AJ (2007). "Papillary thyroid cancer: monitoring and therapy". Endocrinol. Metab. Clin. North Am. 36 (3): 753–78, vii. doi:10.1016/j.ecl.2007.04.004. PMID 17673127.
- ↑ Hurtado-López, LM; Fernández-Ramírez, F; Martínez-Peñafiel, E; Carrillo Ruiz, JD; Herrera González, NE (16 June 2015). "Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early Tumor Marker?". Medical science monitor : international medical journal of experimental and clinical research. 21: 1745–51. PMID 26079849.
- ↑ DeLellis, Ronald (2004). Pathology and genetics of tumours of endocrine organs. Lyon: IARC Press. ISBN 92-832-2416-7.