Secondary amyloidosis risk factors: Difference between revisions
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*** [[TNF Receptor associated periodic syndrome]] ([[TRAPS]]) | *** [[TNF Receptor associated periodic syndrome]] ([[TRAPS]]) | ||
* [[Conditions]] associated with increased risk of secondary amyloidosis include: | * [[Conditions]] associated with increased risk of secondary amyloidosis include: | ||
** Tuberculosis | |||
Tuberculosis | ** Leprosy | ||
Leprosy | ** Whipple Disease | ||
Whipple Disease | ** Osteomyelitis | ||
Osteomyelitis | ** Chronic pyelonephritis | ||
Chronic pyelonephritis | ** Subacute bacterial endocarditis | ||
Subacute bacterial endocarditis | ** Chronic cutaneous ulcers | ||
Chronic cutaneous ulcers | * Conditions Predisposing to Chronic Infections include: | ||
Conditions Predisposing to Chronic Infections | ** Cystic fibrosis | ||
Cystic fibrosis | ** Bronchiectasis | ||
Bronchiectasis | |||
Kartagener syndrome | Kartagener syndrome | ||
Epidermolysis bullosa | Epidermolysis bullosa | ||
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Systemic lupus erythematosus | Systemic lupus erythematosus | ||
Takayasu arteritis | Takayasu arteritis | ||
** Cryopyrin-associated periodic fever syndrome | |||
Cryopyrin-associated periodic fever syndrome | ** Mevalonate kinase deficiency | ||
** Inflammatory Bowel Disease | |||
Mevalonate kinase deficiency | ** Ulcerative colitis | ||
** Crohn diseases | |||
Inflammatory Bowel Disease | * Others include: | ||
Ulcerative colitis | ** Atrial myxoma | ||
Crohn diseases | ** Inflammatory abdominal aortic aneurism | ||
Others | ** Retroperitoneal fibrosis | ||
Atrial myxoma | ** SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome | ||
Inflammatory abdominal aortic aneurism | ** Sarcoidosis | ||
Retroperitoneal fibrosis | ** Sinus histiocytosis with massive lymphadenopathy | ||
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome | ==References== | ||
Sarcoidosis | {{Reflist|2}} | ||
Sinus histiocytosis with massive lymphadenopathy | |||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
The most potent risk factor in the development of secondary amyloidosis is a persistent inflammatory disorders.
Risk Factors
- The most potent risk factor in the development of secondary amyloidosis is a persistent inflammatory disorders.[1]
- chronic infections and inflammatory arthritis are among the most common risk factors.[2][3][4]
- Other possible risk factors include:
- Obesity
- Aging
- SAA1 gene alleles
- Monogenic periodic fever syndromes, such as:
- Conditions associated with increased risk of secondary amyloidosis include:
- Tuberculosis
- Leprosy
- Whipple Disease
- Osteomyelitis
- Chronic pyelonephritis
- Subacute bacterial endocarditis
- Chronic cutaneous ulcers
- Conditions Predisposing to Chronic Infections include:
- Cystic fibrosis
- Bronchiectasis
Kartagener syndrome Epidermolysis bullosa Injected drug abuse Jejuno-ileal bypass Paraplegia Sickle cell anemia Immunodeficiency Common variable immunodeficiency Cyclic neutropenia Hyperimmunoglobulin M syndrome Hypogammaglobulinemia Sex-linked agammaglobulinemia Human immunodeficiency virus/AIDS Neoplasia Adenocarcinoma Basal cell carcinoma Carcinoid tumor Castleman disease Gastrointestinal stromal tumor Hairy cell leukemia Hepatic adenoma Hodgkin disease Mesothelioma Renal cell carcinoma Sarcoma Inflammatory Arthritis Adult-onset Still disease Ankylosing spondylitis Juvenile idiopathic arthritis Psoriatic arthropathy Reiter syndrome Rheumatoid arthritis Gout Systemic Vasculitis Antineutrophil cytoplasmic antibody-associated vasculitis Behc¸et disease Giant cell arteritis Polyarteritis nodosa Polymyalgia rheumatica Systemic lupus erythematosus Takayasu arteritis
- Cryopyrin-associated periodic fever syndrome
- Mevalonate kinase deficiency
- Inflammatory Bowel Disease
- Ulcerative colitis
- Crohn diseases
- Others include:
- Atrial myxoma
- Inflammatory abdominal aortic aneurism
- Retroperitoneal fibrosis
- SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome
- Sarcoidosis
- Sinus histiocytosis with massive lymphadenopathy
References
- ↑ Koivuniemi, Riitta; Paimela, Leena; Suomalainen, Risto; Törnroth, Tom; Leirisalo-Repo, Marjatta (2009). "Amyloidosis is frequently undetected in patients with rheumatoid arthritis". Amyloid. 15 (4): 262–268. doi:10.1080/13506120802524676. ISSN 1350-6129.
- ↑ Blank, Norbert; Hegenbart, Ute; Dietrich, Sascha; Brune, Maik; Beimler, Jörg; Röcken, Christoph; Müller-Tidow, Carsten; Lorenz, Hanns-Martin; Schönland, Stefan O. (2018). "Obesity is a significant susceptibility factor for idiopathic AA amyloidosis". Amyloid. 25 (1): 37–45. doi:10.1080/13506129.2018.1429391. ISSN 1350-6129.
- ↑ van der Hilst, J. C. H.; Yamada, T.; Op den Camp, H. J. M.; van der Meer, J. W. M.; Drenth, J. P. H.; Simon, A. (2008). "Increased susceptibility of serum amyloid A 1.1 to degradation by MMP-1: potential explanation for higher risk of type AA amyloidosis". Rheumatology. 47 (11): 1651–1654. doi:10.1093/rheumatology/ken371. ISSN 1462-0324.
- ↑ Papa, Riccardo; Doglio, Matteo; Lachmann, Helen J.; Ozen, Seza; Frenkel, Joost; Simon, Anna; Neven, Bénédicte; Kuemmerle-Deschner, Jasmin; Ozgodan, Huri; Caorsi, Roberta; Federici, Silvia; Finetti, Martina; Trachana, Maria; Brunner, Jurgen; Bezrodnik, Liliana; Pinedo Gago, Mari Carmen; Maggio, Maria Cristina; Tsitsami, Elena; Al Suwairi, Wafaa; Espada, Graciela; Shcherbina, Anna; Aksu, Guzide; Ruperto, Nicolino; Martini, Alberto; Ceccherini, Isabella; Gattorno, Marco (2017). "A web-based collection of genotype-phenotype associations in hereditary recurrent fevers from the Eurofever registry". Orphanet Journal of Rare Diseases. 12 (1). doi:10.1186/s13023-017-0720-3. ISSN 1750-1172.