Atherosclerosis causes: Difference between revisions
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===Genetic Causes=== | ===Genetic Causes=== | ||
*Atherosclerosis can caused by expression in the PCSK9 gene.<ref name="pmid22176652">{{cite journal| author=Ferri N, Tibolla G, Pirillo A, Cipollone F, Mezzetti A, Pacia S | display-authors=etal| title=Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels. | journal=Atherosclerosis | year= 2012 | volume= 220 | issue= 2 | pages= 381-6 | pmid=22176652 | doi=10.1016/j.atherosclerosis.2011.11.026 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22176652 }} </ref> | *Atherosclerosis can caused by expression in the PCSK9 gene.<ref name="pmid22176652">{{cite journal| author=Ferri N, Tibolla G, Pirillo A, Cipollone F, Mezzetti A, Pacia S | display-authors=etal| title=Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels. | journal=Atherosclerosis | year= 2012 | volume= 220 | issue= 2 | pages= 381-6 | pmid=22176652 | doi=10.1016/j.atherosclerosis.2011.11.026 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22176652 }} </ref> | ||
*Mutation one of the three genes below can cause familal hypercholesterolemia:LDLR,APOB3,PCSK9.<ref name="pmid24585268">{{cite journal| author=Sjouke B, Kusters DM, Kindt I, Besseling J, Defesche JC, Sijbrands EJ | display-authors=etal| title=Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome. | journal=Eur Heart J | year= 2015 | volume= 36 | issue= 9 | pages= 560-5 | pmid=24585268 | doi=10.1093/eurheartj/ehu058 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24585268 }} </ref> | |||
*In human nearly 40 quantitative trait loci have been found for atherosclerosis.<ref name="pmid17767904">{{cite journal| author=Chen Y, Rollins J, Paigen B, Wang X| title=Genetic and genomic insights into the molecular basis of atherosclerosis. | journal=Cell Metab | year= 2007 | volume= 6 | issue= 3 | pages= 164-79 | pmid=17767904 | doi=10.1016/j.cmet.2007.07.001 | pmc=2083632 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17767904 }} </ref> | *In human nearly 40 quantitative trait loci have been found for atherosclerosis.<ref name="pmid17767904">{{cite journal| author=Chen Y, Rollins J, Paigen B, Wang X| title=Genetic and genomic insights into the molecular basis of atherosclerosis. | journal=Cell Metab | year= 2007 | volume= 6 | issue= 3 | pages= 164-79 | pmid=17767904 | doi=10.1016/j.cmet.2007.07.001 | pmc=2083632 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17767904 }} </ref> | ||
Revision as of 15:16, 29 May 2020
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Xyz Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Atherosclerosis causes On the Web |
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American Roentgen Ray Society Images of Atherosclerosis causes |
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Risk calculators and risk factors for Atherosclerosis causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Niloofarsadaat Eshaghhosseiny, MD[2]
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Atherosclerosis Microchapters |
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Diagnosis |
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Treatment |
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ACC/AHA Guideline Recommendations |
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Case Studies |
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Atherosclerosis causes On the Web |
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American Roentgen Ray Society Images of Atherosclerosis causes |
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Risk calculators and risk factors for Atherosclerosis causes |
Overview
Atherosclerosis may be caused by inflamation,immunity or infection.
OR
Common causes of [disease] include [cause1], [cause2], and [cause3].
OR
The most common cause of [disease name] is [cause 1]. Less common causes of [disease name] include [cause 2], [cause 3], and [cause 4].
OR
The cause of [disease name] has not been identified. To review risk factors for the development of [disease name], click here.
Causes
Life-threatening Causes
- Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. There are no life-threatening causes of disease name, however complications resulting from untreated disease name is common.
- Life-threatening causes of [symptom/manifestation] include [cause1], [cause2], and [cause3].
- [Cause] is a life-threatening cause of [disease].
Common Causes
Common causes of atherosclerosis may include:
- Immunity
- Inflamation
- Infections,such as geram negative sepsis,can cause type 2 acute cronary syndrome.[1]
Less Common Causes
Less common causes of [disease name] include:
- [Cause1]
- [Cause2]
- [Cause3]
Genetic Causes
- Atherosclerosis can caused by expression in the PCSK9 gene.[2]
- Mutation one of the three genes below can cause familal hypercholesterolemia:LDLR,APOB3,PCSK9.[3]
- In human nearly 40 quantitative trait loci have been found for atherosclerosis.[4]
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
List the causes of the disease in alphabetical order:
- Cause 1
- Cause 2
- Cause 3
- Cause 4
- Cause 5
- Cause 6
- Cause 7
- Cause 8
- Cause 9
- Cause 10
References
- ↑ Libby P, Loscalzo J, Ridker PM, Farkouh ME, Hsue PY, Fuster V; et al. (2018). "Inflammation, Immunity, and Infection in Atherothrombosis: JACC Review Topic of the Week". J Am Coll Cardiol. 72 (17): 2071–2081. doi:10.1016/j.jacc.2018.08.1043. PMC 6196735. PMID 30336831.
- ↑ Ferri N, Tibolla G, Pirillo A, Cipollone F, Mezzetti A, Pacia S; et al. (2012). "Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels". Atherosclerosis. 220 (2): 381–6. doi:10.1016/j.atherosclerosis.2011.11.026. PMID 22176652.
- ↑ Sjouke B, Kusters DM, Kindt I, Besseling J, Defesche JC, Sijbrands EJ; et al. (2015). "Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome". Eur Heart J. 36 (9): 560–5. doi:10.1093/eurheartj/ehu058. PMID 24585268.
- ↑ Chen Y, Rollins J, Paigen B, Wang X (2007). "Genetic and genomic insights into the molecular basis of atherosclerosis". Cell Metab. 6 (3): 164–79. doi:10.1016/j.cmet.2007.07.001. PMC 2083632. PMID 17767904.