Heartburn natural history, complications and prognosis: Difference between revisions
Jump to navigation
Jump to search
m Bot: Removing from Primary care |
Jose Loyola (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Heartburn}} | {{Heartburn}} | ||
{{CMG}} {{AE}} {{AEL}} {{Jose}} | |||
==Overview== | |||
Natural history of [[heartburn]] depends on its cause. | |||
The most common cause is [[gastroesophageal reflux disease]] ([[GERD]]) which, if left untreated, 20% of patients with GERD may progress to develop [[esophageal stricture]] due to excessive [[acid]] in the [[Esophagus|lower esophagus]]. | |||
Complications of GERD include: | |||
*[[Barrett's esophagus]]; | |||
*[[Esophagitis|erosive esophagitis]]; | |||
*[[Esophageal ulcer]]; | |||
*[[Esophageal]] [[adenocarcinoma]]. | |||
Prognosis of GERD is good with the appropriate treatment. | |||
==Natural History, Complications and Prognosis== | |||
===Natural History=== | |||
* The symptoms of GERD include [[Heartburn|heart burn]], [[regurgitation]], and [[dysphagia]]. | |||
* If left untreated, GERD will develop to [[esophageal stricture]] which occurs in around 20% of the patients with GERD.<ref name="pmid10780569">{{cite journal| author=Sonnenberg A, El-Serag HB| title=Clinical epidemiology and natural history of gastroesophageal reflux disease. | journal=Yale J Biol Med | year= 1999 | volume= 72 | issue= 2-3 | pages= 81-92 | pmid=10780569 | doi= | pmc=2579001 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10780569 }}</ref> | |||
* Esophageal stricture occur due to excessive [[acid]] in the [[Esophagus|lower of the esophagus]] which lead to [[scar]] formation. This scar causes narrowing of the [[esophagus]] and lead to [[Dysphagia|difficulties in swallowing]]. | |||
===Complication=== | |||
Complications that can develop as a result of GERD include the following:<ref name="pmid15929752">{{cite journal| author=El-Serag HB, Graham DY, Satia JA, Rabeneck L| title=Obesity is an independent risk factor for GERD symptoms and erosive esophagitis. | journal=Am J Gastroenterol | year= 2005 | volume= 100 | issue= 6 | pages= 1243-50 | pmid=15929752 | doi=10.1111/j.1572-0241.2005.41703.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15929752 }}</ref> | |||
* [[Barrett's esophagus]]: | |||
** A type of [[dysplasia]], is a precursor high-grade dysplasia, which is in turn a [[precursor]] condition for [[carcinoma]]. The risk of progression from [[Barrett's esophagus|Barrett's]] to dysplasia is uncertain but is estimated to include 0.1% to 0.5% of cases, and has probably been exaggerated in the past. | |||
** Due to the risk of [[Heartburn|chronic heart burn]] progressing to Barrett's esophagus, EGD every 5 years is recommended for patients with chronic [[heartburn]], or who take drugs for chronic GERD. | |||
* [[Esophagitis (patient information)|Erosive esophagitis]] | |||
* [[Esophageal ulcer]]: | |||
** The excess [[acid]] secretion in the [[esophagus]] can lead to [[ulcer]] formation which increases [[pain]] in GERD patients. | |||
* [[Esophageal]] [[adenocarcinoma]] | |||
===Prognosis=== | |||
* The majority of people respond to nonsurgical measures, with lifestyle changes and [[medications]]. However, many patients need to continue to take [[drugs]] to control their symptoms. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | [[Category:Gastroenterology]] | ||
Revision as of 17:28, 4 September 2020
|
Heartburn Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Heartburn natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Heartburn natural history, complications and prognosis |
|
FDA onHeartburn natural history, complications and prognosis |
|
CDC on Heartburn natural history, complications and prognosis |
|
Heartburn natural history, complications and prognosis in the news |
|
Blogs on Heartburn natural history, complications and prognosis |
|
Risk calculators and risk factors for Heartburn natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2] José Eduardo Riceto Loyola Junior, M.D.[3]
Overview
Natural history of heartburn depends on its cause. The most common cause is gastroesophageal reflux disease (GERD) which, if left untreated, 20% of patients with GERD may progress to develop esophageal stricture due to excessive acid in the lower esophagus. Complications of GERD include:
Prognosis of GERD is good with the appropriate treatment.
Natural History, Complications and Prognosis
Natural History
- The symptoms of GERD include heart burn, regurgitation, and dysphagia.
- If left untreated, GERD will develop to esophageal stricture which occurs in around 20% of the patients with GERD.[1]
- Esophageal stricture occur due to excessive acid in the lower of the esophagus which lead to scar formation. This scar causes narrowing of the esophagus and lead to difficulties in swallowing.
Complication
Complications that can develop as a result of GERD include the following:[2]
- Barrett's esophagus:
- A type of dysplasia, is a precursor high-grade dysplasia, which is in turn a precursor condition for carcinoma. The risk of progression from Barrett's to dysplasia is uncertain but is estimated to include 0.1% to 0.5% of cases, and has probably been exaggerated in the past.
- Due to the risk of chronic heart burn progressing to Barrett's esophagus, EGD every 5 years is recommended for patients with chronic heartburn, or who take drugs for chronic GERD.
- Erosive esophagitis
- Esophageal ulcer:
- Esophageal adenocarcinoma
Prognosis
- The majority of people respond to nonsurgical measures, with lifestyle changes and medications. However, many patients need to continue to take drugs to control their symptoms.
References
- ↑ Sonnenberg A, El-Serag HB (1999). "Clinical epidemiology and natural history of gastroesophageal reflux disease". Yale J Biol Med. 72 (2–3): 81–92. PMC 2579001. PMID 10780569.
- ↑ El-Serag HB, Graham DY, Satia JA, Rabeneck L (2005). "Obesity is an independent risk factor for GERD symptoms and erosive esophagitis". Am J Gastroenterol. 100 (6): 1243–50. doi:10.1111/j.1572-0241.2005.41703.x. PMID 15929752.