C4 glomerulopathy screening: Difference between revisions
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==Screening== | ==Screening== | ||
C4 glomerulopathy | There is insufficient evidence to recommend routine screening for C4 glomerulopathy. Quantifying CD46 expression on peripheral blood mononuclear cells for mutations and genes that encrypt complement factors include<ref name="pmid28838767">{{cite journal| author=Zhang Y, Meyer NC, Fervenza FC, Lau W, Keenan A, Cara-Fuentes G | display-authors=etal| title=C4 Nephritic Factors in C3 Glomerulopathy: A Case Series. | journal=Am J Kidney Dis | year= 2017 | volume= 70 | issue= 6 | pages= 834-843 | pmid=28838767 | doi=10.1053/j.ajkd.2017.07.004 | pmc=5701858 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28838767 }} </ref><ref name="pmid26283675">{{cite journal| author=Bu F, Borsa NG, Jones MB, Takanami E, Nishimura C, Hauer JJ | display-authors=etal| title=High-Throughput Genetic Testing for Thrombotic Microangiopathies and C3 Glomerulopathies. | journal=J Am Soc Nephrol | year= 2016 | volume= 27 | issue= 4 | pages= 1245-53 | pmid=26283675 | doi=10.1681/ASN.2015040385 | pmc=4814193 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26283675 }} </ref>: | ||
*CFH | *CFH | ||
*CFI | *CFI |
Revision as of 00:17, 3 August 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Ali Poyan Mehr, M.D. [2]; Associate Editor(s)-in-Chief: Olufunmilola Olubukola M.D.[3]
Overview
Screening
There is insufficient evidence to recommend routine screening for C4 glomerulopathy. Quantifying CD46 expression on peripheral blood mononuclear cells for mutations and genes that encrypt complement factors include[1][2]:
- CFH
- CFI
- CD46 (encoding CD46)
- CFHR1, CFHR2, CFHR3, CFHR4, and CFHR5
- Genes that encode complement activators
- CFB
- C3
References
- ↑ Zhang Y, Meyer NC, Fervenza FC, Lau W, Keenan A, Cara-Fuentes G; et al. (2017). "C4 Nephritic Factors in C3 Glomerulopathy: A Case Series". Am J Kidney Dis. 70 (6): 834–843. doi:10.1053/j.ajkd.2017.07.004. PMC 5701858. PMID 28838767.
- ↑ Bu F, Borsa NG, Jones MB, Takanami E, Nishimura C, Hauer JJ; et al. (2016). "High-Throughput Genetic Testing for Thrombotic Microangiopathies and C3 Glomerulopathies". J Am Soc Nephrol. 27 (4): 1245–53. doi:10.1681/ASN.2015040385. PMC 4814193. PMID 26283675.