Non-bacterial thrombotic endocarditis history and symptoms: Difference between revisions
Aisha Adigun (talk | contribs) |
Aisha Adigun (talk | contribs) |
||
| Line 17: | Line 17: | ||
*Valvular deficiency or heart failure is an uncommon initial presentation<ref name="pmid20397972">{{cite journal |vauthors=Mazokopakis EE, Syros PK, Starakis IK |title=Nonbacterial thrombotic endocarditis (marantic endocarditis) in cancer patients |journal=Cardiovasc Hematol Disord Drug Targets |volume=10 |issue=2 |pages=84–6 |date=June 2010 |pmid=20397972 |doi=10.2174/187152910791292484 |url=}}</ref>. | *Valvular deficiency or heart failure is an uncommon initial presentation<ref name="pmid20397972">{{cite journal |vauthors=Mazokopakis EE, Syros PK, Starakis IK |title=Nonbacterial thrombotic endocarditis (marantic endocarditis) in cancer patients |journal=Cardiovasc Hematol Disord Drug Targets |volume=10 |issue=2 |pages=84–6 |date=June 2010 |pmid=20397972 |doi=10.2174/187152910791292484 |url=}}</ref>. | ||
===History=== | ===History=== | ||
Patients with NBTE may have a positive history of: | Patients with NBTE may have a positive history of<ref name="urlNonbacterial Thrombotic Endocarditis in Cancer Patients: Pathogenesis, Diagnosis, and Treatment - el‐Shami - 2007 - The Oncologist - Wiley Online Library">{{cite web |url=https://theoncologist.onlinelibrary.wiley.com/doi/full/10.1634/theoncologist.12-5-518 |title=Nonbacterial Thrombotic Endocarditis in Cancer Patients: Pathogenesis, Diagnosis, and Treatment - el‐Shami - 2007 - The Oncologist - Wiley Online Library |format= |work= |accessdate=}}</ref><ref name="urlLibman-Sacks Endocarditis Clinical Presentation: History, Physical Examination">{{cite web |url=https://emedicine.medscape.com/article/155230-clinical |title=Libman-Sacks Endocarditis Clinical Presentation: History, Physical Examination |format= |work= |accessdate=}}</ref><ref name="urlNon-bacterial Thrombotic Endocarditis | IntechOpen">{{cite web |url=https://www.intechopen.com/books/infective-endocarditis/non-bacterial-thrombotic-endocarditis |title=Non-bacterial Thrombotic Endocarditis | IntechOpen |format= |work= |accessdate=}}</ref>; | ||
*Malignancy | *Malignancy | ||
*Disseminated intravascular coagulation | *Disseminated intravascular coagulation | ||
Revision as of 16:17, 16 August 2020
|
non-bacterial thrombotic endocarditis |
|
Differentiating non-bacterial thrombotic endocarditis from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Non-bacterial thrombotic endocarditis history and symptoms On the Web |
|
American Roentgen Ray Society Images of Non-bacterial thrombotic endocarditis history and symptoms |
|
FDA on Non-bacterial thrombotic endocarditis history and symptoms |
|
CDC on Non-bacterial thrombotic endocarditis history and symptoms |
|
Non-bacterial thrombotic endocarditis history and symptoms in the news |
|
Blogs on Non-bacterial thrombotic endocarditis history and symptoms |
|
Risk calculators and risk factors for Non-bacterial thrombotic endocarditis history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aisha Adigun, B.Sc., M.D.[2]
Overview
The majority of patients with [disease name] are asymptomatic.
OR
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History and Symptoms
- The majority of patients with non-bacterial thrombotic endocarditis are asymptomatic[1].
- Systemic embolism of the brain, liver, or spleen is a common initial clinical manifestation of NBTE, and occur in more than half of patients[2][3][4].
- The most common presentation of NBTE is a sudden stroke[5].
- About 50% of patients with NBTE present with new or a change in existing cardiac murmurs.
- Murmurs are usually non-specific systolic murmurs commonly located in the left lower sternal border[6].
- Valvular deficiency or heart failure is an uncommon initial presentation[7].
History
Patients with NBTE may have a positive history of[1][8][9];
- Malignancy
- Disseminated intravascular coagulation
- Antiphospholipid syndrome
- Autoimmune disease such as systemic lupus erythematosus
Common Symptoms
In alphabetical order, some of the common manifestations and symptoms of NTBE include:
- Cerebrovascular embolism
- Amnesia
- Delirium
- Dysphagia
- Dysphasia
- Dysarthria
- Localized/diffuse weakness
- Localized/diffuse numbness
- Psychomotor agitation
- Seizures
- Vision loss
- Heart failure secondary to defective valves
- Chest pain
- Dyspnea
- Lethargy
- Orthopnea
- Paroxysmal nocturnal dyspnea
- Peripheral edema
- Symptoms due to underlying SLE;
- Arthritis
- Hematuria
- Rash
- Sweating
- Fatigue
- Systemic thromboembolism
- Acute abdominal syndromes;
- Flank pain due to kidney infarction
- Nausea
- Pain
- Vomiting
- Raynaud's phenomenon due to embolization to the skin
- Acute abdominal syndromes;
Less Common Symptoms
In alphabetical order, some of the less common manifestations and symptoms of NBTE include;
- Secondary infective endocarditis
- Chest pain
- Fever
- Night sweats
- Weightloss
References
- ↑ 1.0 1.1 [+https://doi.org/10.1634/theoncologist.12-5-518 "Nonbacterial Thrombotic Endocarditis in Cancer Patients: Pathogenesis, Diagnosis, and Treatment - el‐Shami - 2007 - The Oncologist - Wiley Online Library"] Check
|url=value (help). - ↑ Edoute Y, Haim N, Rinkevich D, Brenner B, Reisner SA (March 1997). "Cardiac valvular vegetations in cancer patients: a prospective echocardiographic study of 200 patients". Am. J. Med. 102 (3): 252–8. doi:10.1016/S0002-9343(96)00457-3. PMID 9217593.
- ↑ el-Shami K, Griffiths E, Streiff M (May 2007). "Nonbacterial thrombotic endocarditis in cancer patients: pathogenesis, diagnosis, and treatment". Oncologist. 12 (5): 518–23. doi:10.1634/theoncologist.12-5-518. PMID 17522239.
- ↑ "Infective endocarditis | The BMJ".
- ↑ Graus F, Rogers LR, Posner JB (January 1985). "Cerebrovascular complications in patients with cancer". Medicine (Baltimore). 64 (1): 16–35. doi:10.1097/00005792-198501000-00002. PMID 3965856.
- ↑ Rosen P, Armstrong D (January 1973). "Nonbacterial thrombotic endocarditis in patients with malignant neoplastic diseases". Am. J. Med. 54 (1): 23–9. doi:10.1016/0002-9343(73)90079-x. PMID 4682494.
- ↑ Mazokopakis EE, Syros PK, Starakis IK (June 2010). "Nonbacterial thrombotic endocarditis (marantic endocarditis) in cancer patients". Cardiovasc Hematol Disord Drug Targets. 10 (2): 84–6. doi:10.2174/187152910791292484. PMID 20397972.
- ↑ "Libman-Sacks Endocarditis Clinical Presentation: History, Physical Examination".
- ↑ "Non-bacterial Thrombotic Endocarditis | IntechOpen".