Pre-eclampsia medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
*The aim of therapy is starting treatment in [[blood pressure]]≥ 140/90 mmHg in office or clinic and [[blood pressure]] ≥ 135/85 mmHg at home and reaching the target [[systolic blood pressure ]] 110-140 mmHg and [[diastolic blood pressure]] less than 85 mmHg regardless the type of [[hypertension]] in [[pregnancy]]. | *The aim of therapy is starting treatment in [[blood pressure]]≥ 140/90 mmHg in office or clinic and [[blood pressure]] ≥ 135/85 mmHg at home and reaching the target [[systolic blood pressure ]] 110-140 mmHg and [[diastolic blood pressure]] less than 85 mmHg regardless the type of [[hypertension]] in [[pregnancy]]. | ||
==Treatment== | ==Treatment== | ||
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*The mainstay of therapy for [[ preeclampsia]], who have [[proteinuria]] with [[severe hypertension]] or [[hypertension ]] with [[neurologic]] signs and symptoms, is [[magnesium sulfate]] ([[MgSO4]]) for [[convulsion]] prophylaxis. | *The mainstay of therapy for [[ preeclampsia]], who have [[proteinuria]] with [[severe hypertension]] or [[hypertension ]] with [[neurologic]] signs and symptoms, is [[magnesium sulfate]] ([[MgSO4]]) for [[convulsion]] prophylaxis. | ||
* Urgent therapy for [[severe hypertension]]( [[blood pressure]] >160/110) is oral [[nifedipine]] or intravenous [[labetalol]] or [[hydralazine]] or oral [[labetalol]].<ref>{{cite journal|doi=10.1161/HYP.0000000000000065Hypertension.}}</ref> | * Urgent therapy for [[severe hypertension]]( [[blood pressure]] >160/110) is oral [[nifedipine]] or intravenous [[labetalol]] or [[hydralazine]] or oral [[labetalol]].<ref>{{cite journal|doi=10.1161/HYP.0000000000000065Hypertension.}}</ref> | ||
{| class="wikitable" | |||
|- | |||
! Serum [[Magnesium]] Concentration (mg/dL) !! Effect | |||
|- | |||
|5–9 || Therapeutic range | |||
|- | |||
| >9|| Loss of [[patellar reflexes]] | |||
|- | |||
| > 12 || Respiratory paralysis | |||
|- | |||
| > 30 || [[Cardiac arrest]] | |||
|- | |||
|} | |||
==References== | ==References== | ||
Revision as of 12:11, 16 October 2020
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Pre-eclampsia Microchapters |
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Pre-eclampsia medical therapy On the Web |
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American Roentgen Ray Society Images of Pre-eclampsia medical therapy |
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Risk calculators and risk factors for Pre-eclampsia medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Zand, M.D.[2] Ogheneochuko Ajari, MB.BS, MS [3]
Overview
- The aim of therapy is starting treatment in blood pressure≥ 140/90 mmHg in office or clinic and blood pressure ≥ 135/85 mmHg at home and reaching the target systolic blood pressure 110-140 mmHg and diastolic blood pressure less than 85 mmHg regardless the type of hypertension in pregnancy.
Treatment
Medical Therapy
- The mainstay of therapy for hypertension in preeclampsia is oral methyldopa, labetalol, oxprenolol, and nifedipine, and second or third line agents include hydralazine and prazosin.
- The mainstay of therapy for preeclampsia, who have proteinuria with severe hypertension or hypertension with neurologic signs and symptoms, is magnesium sulfate (MgSO4) for convulsion prophylaxis.
- Urgent therapy for severe hypertension( blood pressure >160/110) is oral nifedipine or intravenous labetalol or hydralazine or oral labetalol.[1]
| Serum Magnesium Concentration (mg/dL) | Effect |
|---|---|
| 5–9 | Therapeutic range |
| >9 | Loss of patellar reflexes |
| > 12 | Respiratory paralysis |
| > 30 | Cardiac arrest |
References
- ↑ . doi:10.1161/HYP.0000000000000065Hypertension. Check
|doi=value (help). Missing or empty|title=(help)