Polycythemia medical therapy: Difference between revisions

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Revision as of 19:48, 6 December 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Debduti Mukhopadhyay, M.B.B.S [2]

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 {{Polycythemia}}
 {{CMG}} {{AE}}{{Debduti}}
-==Overview==
-*Phlebotomy is used to decrease blood thickness.
-*Medicines that may be used include:<ref name="pmid31151982">{{cite journal| author=Spivak JL| title=How I treat polycythemia vera. | journal=Blood | year= 2019 | volume= 134 | issue= 4 | pages= 341-352 | pmid=31151982 | doi=10.1182/blood.2018834044 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31151982  }} </ref>
-**Hydroxyurea: it used to reduce red blood cells counts and other blood cells if high. It also used to prevent thrombosis in patients >60 years of age with chronic PV.
-**Interferon: reduce blood cell counts.PegIFN can be used to reduce established splenomegaly but not usually to normal size.
-**Anagrelide: used to treat thrombocytosis.
-**Ruxolitinib (JAK1/2 inhibitor): proved to be effective in PPMF  and chronic-phase PV; provided durable symptom relief, blood count control, and reduction in splenomegaly; and was superior to hydroxyurea.
-**Aspirin: used to prevent thrombosis.
-*Ultraviolet-B light therapy: reduce the itchiness.
 ==Overview==