Dementia resident survival guide: Difference between revisions
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==Overview== | ==Overview== | ||
'''[[Dementia]]''' is the progressive decline in [[cognitive function]] due to damage or disease in the [[brain]] beyond what might be expected from normal aging, it should be [[Disorientation|disoriented]] from [[delirium]] which involves an acute onset, and usually is reversible. [[Dementia]] may affect several [[cognitive]] areas, such as [[memory]], [[attention]], [[language]], and problem-solving. In advanced stages of the condition, affected persons may be [[Disorientation|disoriented]] in time, place, and/or in person. The diagnosis of [[dementia]] is primarily clinical and ruling-out other conditions by imaging and [[Laboratory|laboratory tests]]. It is important to always screen for [[depression]], especially in older people, since this may be the underlying problem. | '''[[Dementia]]''' is the progressive decline in [[cognitive function]] due to damage or disease in the [[brain]] beyond what might be expected from normal aging, it should be [[Disorientation|disoriented]] from [[delirium]] which involves an acute onset, and usually is reversible. [[Dementia]] may affect several [[cognitive]] areas, such as [[memory]], [[attention]], [[language]], and problem-solving. In advanced stages of the condition, affected persons may be [[Disorientation|disoriented]] in time, place, and/or in person. The diagnosis of [[dementia]] is primarily clinical and ruling-out other conditions by imaging and [[Laboratory|laboratory tests]]. It is important to always screen for [[depression]], especially in older people, since this may be the underlying problem. | ||
==Causes== | |||
===Life Threatening Causes=== | ===Life Threatening Causes=== | ||
There are no identified life-threatening causes in [[dementia]] that may lead to death within 24 hours since all conditions are chronic. | There are no identified life-threatening causes in [[dementia]] that may lead to death within 24 hours since all conditions are chronic. |
Revision as of 01:44, 18 February 2021
Dementia Resident Survival Guide Microchapters |
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Overview |
Causes |
Diagnosis |
Treatment |
Do's |
Don'ts |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Moises Romo, M.D.
Synonyms and Keywords: dementia management, dementia workup, dementia approach, approach to dementia, dementia treatment
Overview
Dementia is the progressive decline in cognitive function due to damage or disease in the brain beyond what might be expected from normal aging, it should be disoriented from delirium which involves an acute onset, and usually is reversible. Dementia may affect several cognitive areas, such as memory, attention, language, and problem-solving. In advanced stages of the condition, affected persons may be disoriented in time, place, and/or in person. The diagnosis of dementia is primarily clinical and ruling-out other conditions by imaging and laboratory tests. It is important to always screen for depression, especially in older people, since this may be the underlying problem.
Causes
Life Threatening Causes
There are no identified life-threatening causes in dementia that may lead to death within 24 hours since all conditions are chronic.
Common Causes
- Alzheimer's Disease
- Parkinson's Disease
- Binswanger's Disease
- Dementia with Lewy bodies
- Thiamine deficiency
- Vascular dementia
- Marijuana abuse
- AIDS
- Neurosyphilis
- Normal pressure hydrocephalus
- Vitamin B12 deficiency
- Vitamin B6 deficiency
Diagnosis
Shown below is an algorithm summarizing the diagnosis of amnesia according to the the American Academy of Neurology guidelines:[1]
Progressive decline in cognitive function with chronic onset | |||||||||||||||||||||||||||||||||||||||||||||||||
Severe disimpairment in social functioning? Decline from previous levels of functioning and performance?<be>Symptoms are not explained by major psychiatric disorder? | No | Normal aging | |||||||||||||||||||||||||||||||||||||||||||||||
Dementia | |||||||||||||||||||||||||||||||||||||||||||||||||
Measure vitamin B12, and folate, and TSH | Abnormal? | Yes | Vitamin deficiency, hypothyroidism | ||||||||||||||||||||||||||||||||||||||||||||||
Positive for SIGE CAPS questionary? | Yes | Depression | |||||||||||||||||||||||||||||||||||||||||||||||
Take history and perform physical examination | |||||||||||||||||||||||||||||||||||||||||||||||||
Initial short term memory loss | Vascular risk factors, imaging evidence of cerebrovascular involvement | Young age, behavioral symptoms or language impairment | Bradikinesia or features of parkinsonism,
fluctuating cognition, [[visual hallucinations]] | Dementia occuring 1 year after onset of Parkinson disease | |||||||||||||||||||||||||||||||||||||||||||||
Alzheimer disease | Vascular dementia | Frontotemporal dementia | Dementia with Lewy bodies | Parkinson's disease | |||||||||||||||||||||||||||||||||||||||||||||
Treatment
Treat the underlying cause:
- To view the treatment of Alzheimer disease click here.
- To view the treatment of vascular dementia click here.
- To view the treatment of frontotemporal dementia click here.
- To view the treatment of dementia with Lewy bodies click here.
- To view the treatment of Parkinson's disease click here.
General management of dementia for maintaining brain health according to the American Neurological Asociation is as follows:[2]
Recommendations for maintaining brain health in elderly patients with and without AD |
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Do's
- Perform laboratory testing to exclude potentially reversible causes of amnesia. Initial tests should include a CBC, urine toxicology, thyroid function, folate, and vitamin B12 level.
- When pereforming cognitive assesment, use tests such as MMSE, Mini-cog, MoCA, SIB-8, and AD8.[3][4][5][6]
- When determining level of independence and level of disability, use test such as ADCS–ADL.[7]
- When determining the level of behavioral symptoms, use the NPI-Q test.[8]
- Identify primary caregiver and assess his health, as well as the adequacy of family and other support systems.[2]
- Perform a non-contrasted CT scan to diagnose vascular disease, normal pressure hydrocephalus, tumors, and abscess.[9]
- Perform a minimental status test on physical examination and pay especial attention in concentration domain. Minimental testing has the potential distinguish mild cognitive impairment from dementia.[10]
- Always have in mind depression as a possible cause of memory impairmant. Depression is common cause of amnesia; a SIGE CAPS evaluation may disclose an underlying mood disorder.[11]
Don'ts
- If alcoholism and thiamine deficiency is suspected, do not administer glucose before thiamine. Administration of glucose before thiamine may lead to Wernicke encephalopathy.[12]
References
- ↑ Jahn H (December 2013). "Memory loss in Alzheimer's disease". Dialogues Clin Neurosci. 15 (4): 445–54. PMC 3898682. PMID 24459411.
- ↑ 2.0 2.1 Cummings JL, Isaacson RS, Schmitt FA, Velting DM (March 2015). "A practical algorithm for managing Alzheimer's disease: what, when, and why?". Ann Clin Transl Neurol. 2 (3): 307–23. doi:10.1002/acn3.166. PMID 25815358.
- ↑ Folstein MF, Folstein SE, McHugh PR (November 1975). ""Mini-mental state". A practical method for grading the cognitive state of patients for the clinician". J Psychiatr Res. 12 (3): 189–98. doi:10.1016/0022-3956(75)90026-6. PMID 1202204.
- ↑ Borson S, Scanlan JM, Chen P, Ganguli M (October 2003). "The Mini-Cog as a screen for dementia: validation in a population-based sample". J Am Geriatr Soc. 51 (10): 1451–4. doi:10.1046/j.1532-5415.2003.51465.x. PMID 14511167.
- ↑ Nasreddine ZS, Phillips NA, Bédirian V, Charbonneau S, Whitehead V, Collin I, Cummings JL, Chertkow H (April 2005). "The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment". J Am Geriatr Soc. 53 (4): 695–9. doi:10.1111/j.1532-5415.2005.53221.x. PMID 15817019.
- ↑ Schmitt FA, Saxton JA, Xu Y, McRae T, Sun Y, Richardson S, Li H (2009). "A brief instrument to assess treatment response in the patient with advanced Alzheimer disease". Alzheimer Dis Assoc Disord. 23 (4): 377–83. doi:10.1097/WAD.0b013e3181ac9cc1. PMID 19571727.
- ↑ Schmitt FA, Saxton JA, Xu Y, McRae T, Sun Y, Richardson S, Li H (2009). "A brief instrument to assess treatment response in the patient with advanced Alzheimer disease". Alzheimer Dis Assoc Disord. 23 (4): 377–83. doi:10.1097/WAD.0b013e3181ac9cc1. PMID 19571727.
- ↑ Kaufer DI, Cummings JL, Ketchel P, Smith V, MacMillan A, Shelley T, Lopez OL, DeKosky ST (2000). "Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory". J Neuropsychiatry Clin Neurosci. 12 (2): 233–9. doi:10.1176/jnp.12.2.233. PMID 11001602.
- ↑ Knopman DS, DeKosky ST, Cummings JL, Chui H, Corey-Bloom J, Relkin N, Small GW, Miller B, Stevens JC (May 2001). "Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology". Neurology. 56 (9): 1143–53. doi:10.1212/wnl.56.9.1143. PMID 11342678.
- ↑ Petersen RC, Stevens JC, Ganguli M, Tangalos EG, Cummings JL, DeKosky ST (May 2001). "Practice parameter: early detection of dementia: mild cognitive impairment (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology". Neurology. 56 (9): 1133–42. doi:10.1212/wnl.56.9.1133. PMID 11342677.
- ↑ Squire LR, Zouzounis JA (December 1988). "Self-ratings of memory dysfunction: different findings in depression and amnesia". J Clin Exp Neuropsychol. 10 (6): 727–38. doi:10.1080/01688638808402810. PMID 3235647.
- ↑ Hack, Jason B.; Hoffman, Robert S. (1998). "Thiamine Before Glucose to Prevent Wernicke Encephalopathy: Examining the Conventional Wisdom". JAMA. 279 (8): 583. doi:10.1001/jama.279.8.583a. ISSN 0098-7484.