Acute disseminated encephalomyelitis epidemiology and demographics: Difference between revisions
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*The [[Incidence (epidemiology)|Incidence]] of [[Acute disseminated encephalomyelitis causes|Acute disseminated encephalomyelitis]] is about 1 in 125,000-250,000 people each year, in children younger than 10 years, despite the fact that it is a rare disorder. | *The [[Incidence (epidemiology)|Incidence]] of [[Acute disseminated encephalomyelitis causes|Acute disseminated encephalomyelitis]] is about 1 in 125,000-250,000 people each year, in children younger than 10 years, despite the fact that it is a rare disorder. | ||
*Each year, regional medical centers in the United States, the United Kingdom, and Australia see three to six instances.<ref name="pmid11099444">{{cite journal| author=Dale RC, de Sousa C, Chong WK, Cox TC, Harding B, Neville BG| title=Acute disseminated encephalomyelitis, multiphasic disseminated encephalomyelitis and multiple sclerosis in children. | journal=Brain | year= 2000 | volume= 123 Pt 12 | issue= | pages= 2407-22 | pmid=11099444 | doi=10.1093/brain/123.12.2407 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11099444 }}</ref><ref name="pmid11376179">{{cite journal| author=Hynson JL, Kornberg AJ, Coleman LT, Shield L, Harvey AS, Kean MJ| title=Clinical and neuroradiologic features of acute disseminated encephalomyelitis in children. | journal=Neurology | year= 2001 | volume= 56 | issue= 10 | pages= 1308-12 | pmid=11376179 | doi=10.1212/wnl.56.10.1308 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11376179 }}</ref> | *Each year, regional medical centers in the United States, the United Kingdom, and Australia see three to six instances.<ref name="pmid11099444">{{cite journal| author=Dale RC, de Sousa C, Chong WK, Cox TC, Harding B, Neville BG| title=Acute disseminated encephalomyelitis, multiphasic disseminated encephalomyelitis and multiple sclerosis in children. | journal=Brain | year= 2000 | volume= 123 Pt 12 | issue= | pages= 2407-22 | pmid=11099444 | doi=10.1093/brain/123.12.2407 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11099444 }}</ref><ref name="pmid11376179">{{cite journal| author=Hynson JL, Kornberg AJ, Coleman LT, Shield L, Harvey AS, Kean MJ| title=Clinical and neuroradiologic features of acute disseminated encephalomyelitis in children. | journal=Neurology | year= 2001 | volume= 56 | issue= 10 | pages= 1308-12 | pmid=11376179 | doi=10.1212/wnl.56.10.1308 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11376179 }}</ref><ref name="pmid12165620">{{cite journal| author=Murthy SN, Faden HS, Cohen ME, Bakshi R| title=Acute disseminated encephalomyelitis in children. | journal=Pediatrics | year= 2002 | volume= 110 | issue= 2 Pt 1 | pages= e21 | pmid=12165620 | doi=10.1542/peds.110.2.e21 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12165620 }}</ref> | ||
===Prevalence=== | ===Prevalence=== | ||
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===Gender=== | ===Gender=== | ||
* | *Acute disseminated encephalomyelitis affects [https://www.wikidoc.org/index.php/Male males] and [https://www.wikidoc.org/index.php/Female females] Males are more likely than females to contract the disease (male to female ratio of 1.3:1), and it happens more frequently in the winter and spring (historically, the colder months of the year). | ||
===Race=== | ===Race=== | ||
*There is no [https://www.wikidoc.org/index.php/Racial racial] predilection to the development of retinoblastoma.<ref name="pmid9544909" /> | *There is no [https://www.wikidoc.org/index.php/Racial racial] predilection to the development of retinoblastoma.<ref name="pmid9544909">{{cite journal| author=Abramson DH, Frank CM, Susman M, Whalen MP, Dunkel IJ, Boyd NW| title=Presenting signs of retinoblastoma. | journal=J Pediatr | year= 1998 | volume= 132 | issue= 3 Pt 1 | pages= 505-8 | pmid=9544909 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9544909 }}</ref> | ||
===Region=== | ===Region=== |
Revision as of 21:54, 26 June 2021
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Overview
Epidemiology and Demographics
Incidence
- The Incidence of Acute disseminated encephalomyelitis is about 1 in 125,000-250,000 people each year, in children younger than 10 years, despite the fact that it is a rare disorder.
- Each year, regional medical centers in the United States, the United Kingdom, and Australia see three to six instances.[1][2][3]
Prevalence
- There is no data on the prevalence of Acute disseminated encephalomyelitis.
Case-fatality rate/Mortality rate
- The mortality rate of retinoblastoma differs according to the stage of the disease as well as the geographic region.[4]
- In extraocular form of this disorder is reported to be greater than 50%.[5]
- However, tumors involving the optic disc superficially, are associated with 10% mortality rate.[6]
Age
- In youngsters, the usual age of onset is 3 to 7 years.
- Cases have also been reported in children between the ages of 10 and twenty.
- Adults between the ages of 18 and 82 are also affected.[7]
Gender
- Acute disseminated encephalomyelitis affects males and females Males are more likely than females to contract the disease (male to female ratio of 1.3:1), and it happens more frequently in the winter and spring (historically, the colder months of the year).
Race
Region
- Epidemiological data indicates that retinoblastoma has a higher incidence in some geographic areas.[9]
- The table below provides the highest worldwide incidence rate of retinoblastoma in children aged 0 - 4:
References
- ↑ Dale RC, de Sousa C, Chong WK, Cox TC, Harding B, Neville BG (2000). "Acute disseminated encephalomyelitis, multiphasic disseminated encephalomyelitis and multiple sclerosis in children". Brain. 123 Pt 12: 2407–22. doi:10.1093/brain/123.12.2407. PMID 11099444.
- ↑ Hynson JL, Kornberg AJ, Coleman LT, Shield L, Harvey AS, Kean MJ (2001). "Clinical and neuroradiologic features of acute disseminated encephalomyelitis in children". Neurology. 56 (10): 1308–12. doi:10.1212/wnl.56.10.1308. PMID 11376179.
- ↑ Murthy SN, Faden HS, Cohen ME, Bakshi R (2002). "Acute disseminated encephalomyelitis in children". Pediatrics. 110 (2 Pt 1): e21. doi:10.1542/peds.110.2.e21. PMID 12165620.
- ↑ Dimaras, Helen; Kimani, Kahaki; Dimba, Elizabeth AO; Gronsdahl, Peggy; White, Abby; Chan, Helen SL; Gallie, Brenda L (2012). "Retinoblastoma". The Lancet. 379 (9824): 1436–1446. doi:10.1016/S0140-6736(11)61137-9. ISSN 0140-6736.
- ↑ Kim, J W; Kathpalia, V; Dunkel, I J; Wong, R K; Riedel, E; Abramson, D H (2008). "Orbital recurrence of retinoblastoma following enucleation". British Journal of Ophthalmology. 93 (4): 463–467. doi:10.1136/bjo.2008.138453. ISSN 0007-1161.
- ↑ Chévez-Barrios, Patricia; Eagle, Ralph C.; Marback, Eduardo F. (2015). "Histopathologic Features and Prognostic Factors": 167–183. doi:10.1007/978-3-662-43451-2_16.
- ↑ "StatPearls". 2021. PMID 28613684.
- ↑ Abramson DH, Frank CM, Susman M, Whalen MP, Dunkel IJ, Boyd NW (1998). "Presenting signs of retinoblastoma". J Pediatr. 132 (3 Pt 1): 505–8. PMID 9544909.
- ↑ Singh, Arun (2007). Clinical ophthalmic oncology. Edinburgh: Elsevier Saunders. ISBN 978-1-4160-3167-3.