Acute disseminated encephalomyelitis causes: Difference between revisions
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{{Acute disseminated encephalomyelitis}} | {{Acute disseminated encephalomyelitis}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} | ||
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==Overview== | ==Overview== | ||
In the vast majority of cases, the causal pathogen is unknown. Acute disseminated encephalomyelitis is a clinical illness that can be roughly classified as encephalomyelitis with numerous inflammatory demyelination, autoimmune reasons, and a connection to a previous infection or vaccine. | |||
==Causes== | ==Causes== | ||
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*Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory demyelinating multifocal disease of the central nervous system that most commonly affects children after immunization or viral infections of respiratory or gastrointestinal tracts and carries a high risk of neurological sequelae if not treated promptly.<ref name="pmid30753808">{{cite journal| author=Alves JM, Marques IB, Gil-Gouveia R| title=[Vaccination Controversies: An Adult Case of Post-Vaccinal Acute Disseminated Encephalomyelitis]. | journal=Acta Med Port | year= 2019 | volume= 32 | issue= 1 | pages= 81-85 | pmid=30753808 | doi=10.20344/amp.9809 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30753808 }}</ref> | * Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory demyelinating multifocal disease of the central nervous system that most commonly affects children after immunization or viral infections of respiratory or gastrointestinal tracts and carries a high risk of neurological sequelae if not treated promptly.<ref name="pmid30753808">{{cite journal| author=Alves JM, Marques IB, Gil-Gouveia R| title=[Vaccination Controversies: An Adult Case of Post-Vaccinal Acute Disseminated Encephalomyelitis]. | journal=Acta Med Port | year= 2019 | volume= 32 | issue= 1 | pages= 81-85 | pmid=30753808 | doi=10.20344/amp.9809 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30753808 }}</ref> | ||
*Common causes are cytomegalovirus, Epstein-Barr virus, herpes simplex virus, human herpes-virus-6, influenza virus, hepatitis A, human immunodeficiency virus, and mycoplasma pneumonia. | |||
*Common causes are cytomegalovirus, Epstein-Barr virus, herpes simplex virus, human herpes-virus-6, influenza virus, hepatitis A, human immunodeficiency virus, and mycoplasma pneumonia.<ref name="pmid30753808">{{cite journal| author=Alves JM, Marques IB, Gil-Gouveia R| title=[Vaccination Controversies: An Adult Case of Post-Vaccinal Acute Disseminated Encephalomyelitis]. | journal=Acta Med Port | year= 2019 | volume= 32 | issue= 1 | pages= 81-85 | pmid=30753808 | doi=10.20344/amp.9809 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30753808 }} </ref> | |||
*The rabies vaccine was the first vaccine to be linked to acute disseminated encephalomyelitis <ref name="pmid30730236">{{cite journal| author=Rossor T, Benetou C, Wright S, Duignan S, Lascelles K, Robinson R | display-authors=etal| title=Early predictors of epilepsy and subsequent relapse in children with acute disseminated encephalomyelitis. | journal=Mult Scler | year= 2020 | volume= 26 | issue= 3 | pages= 333-342 | pmid=30730236 | doi=10.1177/1352458518823486 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30730236 }}</ref> | *The rabies vaccine was the first vaccine to be linked to acute disseminated encephalomyelitis <ref name="pmid30730236">{{cite journal| author=Rossor T, Benetou C, Wright S, Duignan S, Lascelles K, Robinson R | display-authors=etal| title=Early predictors of epilepsy and subsequent relapse in children with acute disseminated encephalomyelitis. | journal=Mult Scler | year= 2020 | volume= 26 | issue= 3 | pages= 333-342 | pmid=30730236 | doi=10.1177/1352458518823486 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30730236 }}</ref> | ||
==References== | ==References== | ||
Revision as of 02:44, 1 November 2021
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Acute disseminated encephalomyelitis Microchapters |
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Differentiating Acute disseminated encephalomyelitis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
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Overview
In the vast majority of cases, the causal pathogen is unknown. Acute disseminated encephalomyelitis is a clinical illness that can be roughly classified as encephalomyelitis with numerous inflammatory demyelination, autoimmune reasons, and a connection to a previous infection or vaccine.
Causes
- Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory demyelinating multifocal disease of the central nervous system that most commonly affects children after immunization or viral infections of respiratory or gastrointestinal tracts and carries a high risk of neurological sequelae if not treated promptly.[1]
- Common causes are cytomegalovirus, Epstein-Barr virus, herpes simplex virus, human herpes-virus-6, influenza virus, hepatitis A, human immunodeficiency virus, and mycoplasma pneumonia.[1]
- The rabies vaccine was the first vaccine to be linked to acute disseminated encephalomyelitis [2]
References
- ↑ 1.0 1.1 Alves JM, Marques IB, Gil-Gouveia R (2019). "[Vaccination Controversies: An Adult Case of Post-Vaccinal Acute Disseminated Encephalomyelitis]". Acta Med Port. 32 (1): 81–85. doi:10.20344/amp.9809. PMID 30753808.
- ↑ Rossor T, Benetou C, Wright S, Duignan S, Lascelles K, Robinson R; et al. (2020). "Early predictors of epilepsy and subsequent relapse in children with acute disseminated encephalomyelitis". Mult Scler. 26 (3): 333–342. doi:10.1177/1352458518823486. PMID 30730236.